Karvea Duo, Irbesartan/ Amlodipine

Amlodipine is used in the treatment of hypertension (high blood pressure), Amlodipine can help lower blood pressure in patients suffering from hypertension.

Amlodipine is also known as calcium channel blockers or calcium ion antagonists, Amlodipine works in the body by widening the blood vessels, mwhich makes it easier for the heart to pump blood around the body and help increase the supply of blood and oxygen to the heart. Amlodipine as Calcium channel blockers do not change the amount of calcium in your blood or bones. Amlodipine works by blocking the amount of calcium that goes into the 'smooth' muscle cells in the walls of the arteries and in the heart. Calcium is needed for muscles to contract, so reducing the amount of calcium causes the muscle cells to relax, allowing more smoother blood flow and directly treating hypertension

Patients who take Amlodipine may suffer from such side effects;

Fatigue,
Sleepiness,
Flushing (sense of warmth in the face, ears, neck),
Headache,
Ankle swelling,
Nausea,
Dizziness,
Palpitations,
Edema,
Abdominal pain

Irbesartan is used in the treatment of increased blood pressure, heart failure, heart attack and diabetic kidney disease.

Irbesartan is known as an angiotensin II receptor antagonist. Irbesartan works by preventing the blood vessels from narrowing so it helps to improve blood flow. Angiotensin II is a type of vasoconstrictor which means that it causes tightening of the blood vessels which contributes to hypertension. Irbesartan relaxes the blood vessels which lowers the blood pressure and also reduces the workload of the heart. As a result, the heart works more efficiently.

Patients who take Irbesartan may suffer from such side effects;

Vertigo,
Diarrhea,
Orthostatic hypotension,
Tiredness,
Stomach upset,
Digestive disruption