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Methotrexate

Methotrexate is an antimetabolite that is prescribed, alone or together with other agents, to help treat certain types of cancer. It is also prescribed for the treatment of severe psoriasis or severe active rheumatoid arthritis that cannot be controlled by other treatments.
US Brand Name Rheumatrex
Generic Name Methotrexate
Other Brand Name Imutrex
Manufacturer IPCA Laboratories , Cipla
Packing 10
Form Pills
Strength 2.5 mg, 7.5 mg

  • 10 tablets 2.5 mg $3.90
  • 10 tablets 7.5 mg $8.90
  • 4 tablets 10 mg $4.90
Available online
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  • Imutrex, Generic  Rheumatrex ,  Methotrexate 7.5 Mg Tablets (Cipla)
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  • Imutrex, Generic  Rheumatrex , Methotrexate 7.5 mg tablet

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Details

Methotrexate

Uses

Methotrexate is used in the treatment of blood cancer, breast cancer, lung cancer, head and neck cancer, bone cancer, non-hodgkin lymphoma (nhl), cervical cancer, ovarian cancer and testicular cancer. Methotrexate is also used to treat severe psoriasis and rheumatoid arthritis.

How it Works

Methotrexate works by interfering with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells. Methotrexate works in autoimmune diseases by decreasing the activity of body's immune system and prevents the body from attacking itself.

Common Side effects

Some of the potential side effects of Methotrexate can include the symptoms below;

Nausea,
Vomiting,
Loss of appetite,
Dyspepsia,
Black, tarry stools,
Blood in the urine or stools,
Bloody vomit,
Diarrhea,
Joint pain,
Reddening of the skin,
Sores in the mouth or lips,
Swelling of the feet or lower legs,
Abdominal pain,
Increased liver enzymes,
Stomatitis

Introduction

Methotrexate is a drug that is to be used with caution since it may lead to life-threatening complications. It is indicated to treat severe psoriasis, rheumatoid arthritis, or certain forms of cancer when other treatments have proven to be ineffective. It belongs to the class of drugs called antimetabolites.

Use

Before being prescribed this medicine, the possible side effects must be discussed with your doctor. It is often only prescribed when the benefits outweigh the complications. It can be indicated, alone or with other drugs, for the treatment of psoriasis, rheumatoid arthritis, certain forms of cancers like leukemia, lymphoma, breast cancer, lung cancer, cancer of the head and neck, etc.

Dosage and administration

Methotrexate is available as tablets of 2.5 mg, 7.5 mg, or 10 mg concentrations. It is mandatory to follow the doctor’s instructions while taking this drug. Do not take more than the prescribed dose.

For rheumatoid arthritis and psoriasis, the recommended daily dose in an adult is a single oral dose of the 7.5 mg tablet that is to be taken once a week. It may require 4 to 6 weeks for the drug to show its benefits.

The dose for cancer treatment is highly varied and is given for a few days followed by a period of drug abstinence for some weeks. The drug can be taken until the side effects becomes unbearable or consumption of the drug starts showing no benefits.

Warning

  • Tell your doctor if you are allergic to this drug or to any other substances.
  • Tell your doctor if you have any history of lung problems, kidney problems, liver disorders, suppressed bone marrow function, immunity deficiencies, etc., or any active infections because the continued use of this drug is going to affect such conditions.
  • The drug is going to make your skin extremely sensitive to sunlight, hence avoid long exposure to sunlight and take all necessary precautions before going out.
  • This drug is known to decrease your alertness, hence you are advised not to drive after taking the drug.
  • Stay away from all highly infectious people when taking this drug.
  • The drug is known to cause teratogenic effects on the fetus, hence you should avoid pregnancy if you are on this drug regime. Breast feeding is also contraindicated.
  • Avoid going for any vaccinations or immunization if you are on this drug regime. Furthermore, avoid getting bruised or wounded since the drug reduces your body’s immunity to fight infections.
  • The drug is known to cause hypertension, hence the blood pressure of all patients on this drug regime must be closely monitored.
  • Side effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach pain
  • Drowsiness
  • Loss of appetite
  • Weight loss
  • Hair loss
  • Headaches
  • Swollen gums
  • Customer Reviews

    Rated: 5.0 / 5 based on 1 customer reviews.

    Excellent Service and Product

    Posted by Mary on 5/25/17 7:32 AM

    I can't believe how quickly I received my order, and found communicating with Buy Pharma, (thank you Robert!) to be easy and so helpful. It arrived carefully packaged, and intact, and I love the way the medication is in sealed blister packs, and easy to remove. This is the same medication I have been using and have ordered other things from this company with which I am very satisfied. I feel very fortunate to have found this company! I will definitely order again from Buy Pharma.

    Note: buy-pharma.md does not imply any medical claims from this review.