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Oxcarbazepine

Oxcarbazepine is an anticonvulsant that is prescribed, alone or along with other agents, to help treat partial seizures.
US Brand Name Trileptal
Generic Name Oxcarbazepine
Other Brand Name Oxcarb, Trioptal, Oleptal
Manufacturer Novartis
Packing 10
Form Tablet
Strength 150 mg, 300 mg, 600 mg

  • 50 tabs 150 mg $21.00
  • 50 tabs 300 mg $34.50
  • 50 tabs 600 mg $49.50
  • 50 tabs 600 mg OD $86.00
Available online
More Views
  • Oleptal-600, Generic Trileptal, Oxcarbazepine, 600 mg, Box
  • Oleptal-600, Generic Trileptal, Oxcarbazepine, 600 mg, Box description
  • Oleptal-600, Generic Trileptal, Oxcarbazepine, 600 mg, Strip
  • Oleptal-600, Generic Trileptal, Oxcarbazepine, 600 mg, Strip description
  • Trioptal 150, Generic Trileptal, Oxcarbazepine, Tablet
  • Trioptal 150, Generic Trileptal, Oxcarbazepine, Box description
  • Trioptal 150, Generic Trileptal, Oxcarbazepine, Novartis manufacturer
  • Oxcarbazepine
  • Trioptal 300, Generic Trileptal, Oxcarbazepine, Box description
  • Trioptal 300, Generic Trileptal, Oxcarbazepine, Novartis manufacturer
  • Oxcarb-300, Generic Trileptal, Oxcarbazepine, 300 mg, Tablet
  • Oxcarb-300, Generic Trileptal, Oxcarbazepine, 300 mg, Box
  • Oxcarb-300, Generic Trileptal, Oxcarbazepine, 300 mg, Box description
  • Oxcarb-300, Generic Trileptal, Oxcarbazepine, 300 mg, Strip
  • Oxcarb-300, Generic Trileptal, Oxcarbazepine, 300 mg, Strip description
  • Trioptal 600, Generic Trileptal, Oxcarbazepine, 600 mg, Tablet
  • Trioptal 600, Generic Trileptal, Oxcarbazepine, 600 mg, Box description
  • Trioptal 600, Generic Trileptal, Oxcarbazepine, 600 mg, Encore Healthcare manufacturer

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Details

Oxcarbazepine

Uses

Oxcarbazepine is used in the treatment of epilepsy and the seizures it can cause.

How it Works

Oxcarbazepine works by stabilizing the electrical activity of your brain, which prevents the seizures from occurring. A burst of abnormal electrical activity in the brain causes seizures. Oxcarbazepine works by stabalizing this activity thus preventing seizures

Common Side effects

Some of the potential side effects of Oxcarbazepine can include the symptoms below;

Fatigue,
Sleepiness,
Headache,
Nausea,
Vomiting,
Double vision,
Dizziness

Introduction

Oxcarbazepine is an anti-epileptic drug used for the treatment of seizures. It is available in the form of tablets in the strengths of 150 mg, 300 mg, and 600 mg that are to be taken orally. It is also available as a 60 mg/ml oral suspension.

Use

This drug is used to decrease the frequency of epileptic episodes. It is also used along with other drugs to treat the problem of partial seizures. It is also used in the treatment of bipolar disorders where the person often gets mood swings. Oxcarbazepine, when metabolized into 10-monohydroxy metabolite (MHD), blocks the voltage gated sodium channels thereby stopping the propagation of synaptic impulse across the neural membranes of the brain cells. This gives it the property to control seizures. Additionally, increase in the potassium release and calcium conductivity leads to anti-convulsant effects.

Dosage and administration

It is given on a twice a day regimen.

For adults: -

It is usually prescribed as 600 mg tablets that are to be given twice a day. If required, the dose can be increased to 1200 mg, twice a day, making it a daily dose of 2400 mg. The maximum dose should be gradually attained over a period of 2-4 weeks.

For pediatric patients: -

The drug should be initiated at a daily dose of 600 mg that is to be divided into two doses per day. The maintenance dose depends on the body weight and should be given accordingly:

20-30 kg: 900 mg/day
30-40 kg: 1200 mg/day
More than 40 kg: 1800 mg/day

Warning

  • Inform your doctor if you have any history of liver disease or mineral imbalance in the body, or any allergy to this drug or any other substances.
  • The drug makes you feel drowsy hence you are advised not to drive or use any machinery, or perform any tasks which require active mental abilities.
  • It may lead to hyponatremia (excessively reduced sodium levels in the body) hence the body sodium levels must be continuously monitored and in case of symptoms like confusion, double vision, body imbalance, excessive headaches, malaise etc., the drug should be discontinued and the doctor must be contacted immediately.
  • You are advised not to conceive a child if you are on this drug regime.
  • The use of this drug should not be discontinued without consulting your doctor since sudden withdrawal may increase the frequency of epileptic episodes and seizures.
  • Patients on AEDs (anti epileptic drugs) have shown an increased tendency of suicidal behavior, depression, and mood swings hence such patients must be continuously monitored to note their behavioral changes.
  • Side effects

  • Nausea and vomiting
  • Dizziness
  • Drowsiness
  • Headaches
  • Difficulty sleeping
  • Stomach pain
  • Constipation
  • Ataxia
  • Abnormal vision
  • Mood swings
  • Nervousness
  • Difficulty in concentrating and balancing