• Divalproex
  • Generic Depakote, Divalproex

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Divalproex is prescribed, alone or in combination with other drugs, to treat complex partial seizures as well as simple and complex absence seizures. It can also be prescribed to treat manic episodes of bipolar disorder, and to prevent migraine headaches.
US Brand Name Depakote
Generic Name Divalproex
Other Brand Name Dicorate ER 500, Dproex ER 250, Valance, Trend XR
Manufacturer Torrent
Packing 10
Form Pills
Strength 500 mg, 250 mg, 125 mg

  • 50 tabs 125 mg $9.50
  • 50 tabs 250 mg $17.50
  • 50 tabs 500 mg $34.50
  • 50 tabs 750 mg $39.50
  • 50 tabs 1000 mg $49.50
Available online
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  • Valance OD 1g, Geneiric Depakote, Divalproex Sodium ER, 1000 mg, Box Description
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Divalproex is used to treat bipolar disorders, epilepsy and seizures, mania and to prevent migraine headaches.

How it Works

Divalproex is an anticonvulsant. Divalproex works by reducing bursts of abnormal electrical activity in the brain which causes seizures.

Common Side effects

Some of the potential side effects of Divalproex can include the symptoms below;

Loss of appetite,
Hair loss,
Weight gain,
Liver function abnormal,


Depakote is an anti-seizure medication. It is used synergistically with other anti-seizure drugs. The generic name of this drug is divalproex sodium. Abbott Laboratories is the manufacturer and distributor of Depakote. Other popular trade names are Dicorate ER 500, Dproex ER 250, Valance, Depakene, Depacon, and Stavzor. You need doctor's prescription upon purchasing this drug.


The primary composition of Depakote is divalproex sodium. This compound has a distinct odour, comes in a powder form, and is white. Silica gel, vanillin, povidone, talc, titanium dioxide, diacetylated monoglycerides, and cellulosic polymers are the inactive components of the substance.


The drug is used for bipolar disorder patient manic type. It can also be used for patients with a migraine, epilepsy, and severe restlessness condition such as mania.

Dosage and administration

The product comes in many forms, such as injection 100 mg per 5 mL, capsules in 250 mg strength, extended-release tablet in 250 mg and 500 mg strength, delayed release 125mg, 250 mg, and 500 mg strength, sprinkle capsule 125 mg, and syrup 250 mg per 5 mL. Oral administration is the route for the tablet, capsule, and syrup form. For treatment of manic patients, the suggested dosage is 750 mg a day. Titrating of dosage depends on the patient's tolerance and response to Depakote therapy. For epileptic patients 10 years old and above the starting dose depends on the body weight ideally 15 mg/kg/ a day. For patients suffering from migraine attacks, the recommended dosage is 250 mg two times a day. The Depakote 125 mg comes as pink tablet. The 250 mg of Depakote come in peach colour. The 500 mg comes in lavender colour.


Patient with known hypersensitivity to divalproex and any of its components as mentioned above are not encouraged to use this drug. It is contraindicated for patients with urea cycle disorders

Important Precautions

It is always advisable to take precautionary measures for patients who have allergic reactions to Depakote. Refer to your physician and inform them regarding the drugs that you are using either vitamins, food supplement, or over the counter drugs. Inform your physician right away if you have any history of urea cycle disorder in the family. It is also important to tell the medical health provider if you are pregnant or breastfeeding while undergoing this therapy. Avoid operating heavy equipment or driving while undergoing this treatment as this medication can cause drowsiness and hamper your alertness levels. Expect mood swings under Depakote treatment. The patient is advised to drink fluids more than usual.

Side effects

Common mild adverse side effects of this drug are agitation, diarrhoea, constipation, drowsiness, grogginess, headache, loss of memory, involuntary movement of the body, diplopia or double vision, blurring of vision, tinnitus or ringing in the ear, alopecia or hair loss, and sore throat. Seek medical attention right away for any worsening of symptoms such as bleeding as seen in the stool in the form of melena, itching of the skin, severe depression, and blister.


Keep the medicine is a cool and dry place with a temperature of 30 degree Celsius. Keep away from moisture. Refer to drug literature from time to time for proper drug handling.