How Does Invokana Work?
If you have diabetes, you may be wondering how does Invokana work. This SGLT2 inhibitor works to lower blood sugar by blocking glucose absorption in the kidneys. However, there are some caveats to this medication. Pregnancy and use during childbirth are not recommended. Furthermore, this medicine can cause lower limb amputations. Read on to learn more about how this medication works and what you need to know before starting it.
Invokana is a sodium glucose co-transporter 2 (SGLT2) inhibitor
Invokana is a Type 2 diabetes medication that belongs to a class of drugs known as sodium-glucose co-transporter 2 (SGLT2) enzyme inhibitors. Invokana has a number of possible side effects, and it should only be used in combination with diet and exercise. Taking Invokana may increase your risk of diabetic ketoacidosis, which can lead to amputation and kidney damage.
Invokana, which is marketed by Janssen Pharmaceuticals, is the first SGLT2 inhibitor to be approved by the U.S. Food and Drug Administration. And buy Invokana 100mg On Buy-Pharma.md. Because this has been trusted Pharmacy Since 2003. It is a new class of drugs that reduces blood sugar levels, but some people may experience eye, kidney, nervous system, or cardiovascular side effects. Despite these side effects, SGLT2 inhibitors are widely used for diabetes.
Invokana is only approved by the FDA for Type 2 diabetes, but it has other uses. It has been used to treat heart failure and lower abnormal blood glucose levels in people with Type 2 diabetes. While this drug is FDA-approved for the treatment of Type 2 diabetes, some people are concerned that it could cause heart problems. Aside from its side effects, Invokana has a higher risk of lower limb amputation than other diabetes medications.
It reduces blood sugar by blocking glucose absorption in the kidneys
Invokana is used to lower blood sugar in people with diabetes, insulin resistance, or both. It works by blocking the action of a protein called sodium-glucose co-transporter 2 (SGLT2), which prevents the kidney from absorbing glucose. As a result, filtered glucose is excreted in the urine. However, this medication has been linked to an increased risk of lower-limb amputation. People with a history of amputation may be at a greater risk. Also, those with heart disease, kidney damage, or narrowed blood vessels may be at a higher risk.
Invokana can be taken before or after eating a meal. It helps prevent blood sugar spikes after eating. In type 2 diabetes, the insulin responsible for regulating blood sugar levels moves sugar from the blood into cells and uses it for energy. When insulin isn't working properly or insufficiently, blood sugar levels rise, which damages blood vessels and affects the heart and kidneys.
It is not prescribed during pregnancy
It is unclear why Invokana is not prescribed during pregnancy. The drug is approved for the treatment of diabetes during the first three trimesters of pregnancy, but it is not prescribed during the second and third trimesters. It has been linked to fetal harm in laboratory tests and animal studies. Pregnancy is a time of high risk for the mother, the fetus, and the uterus. Because of these risks, Invokana should only be used if the benefits of the medication outweigh the risks of pregnancy.
Women taking Invokana should know that the drug increases the risk of genital yeast infections. It also increases the risk of Fournier's gangrene, which is an infection that occurs when there is a lack of blood flow in the genital area. People who have a history of genital yeast infections are at higher risk for this side effect. Males without circumcision may also be at a higher risk for this side effect.
It can cause lower limb amputations
The drug Invokana has been linked to increased risk of lower limb amputations, primarily of the toe or foot. Some people have had multiple amputations on one or both sides of their body. Those with heart disease, narrow blood vessels, or damaged nerves are also more susceptible to lower limb amputations. However, the FDA does not know exactly why this drug is linked to increased amputation risk.
Amputations are not a common side effect of Invokana, but users of this drug should talk with their doctors about any possible risks and benefits before taking the drug. Some diabetic patients are at increased risk for amputations. They may have heart failure, blockage of blood vessels in the leg, or a history of previous amputations. Diabetics should discuss their risk factors with their physicians and make sure that they follow their treatment plan. The drug is also known to increase the risk of genital yeast infections, although these are usually mild.