Metformin is a biguanide that is prescribed, alone or along with other agents, to help regulate blood sugar levels in individuals with type 2 diabetes mellitus.



Glycome, Okamet, Metmin, Glumet, Gluformin I, Glyciphage, Glifor, Glukofen


USV, Cipla, Jenburkt Pharma, Abbott, Franco-Indian Pharma, Sandoz


250 mg, 500 mg, 850 mg, 1,000 mg

India, Turkey


Metformin is used in the treatment of type 2 diabetes.
How it Works
Metformin helps in allowing the body to make full use of the reduced amount of Insulin that occurs in type 2 diabetes patients. Insulin occurs naturally in the body's pancreas which helps to control the level of glucose(Sugars) in your blood, insufficient or inaffective insulin results in the condition called diabetes mellitus. Metformin helps in treatment of the type 2 diabetes.
Common Side effects
Patients who take Metformin may suffer from such side effects; Headache, Bloating, Flushing, Changes in the nails, Altered taste, Abdominal pain, Diarrhoea, Loss of appetite, A metallic taste in the mouth, Nausea, Vomiting
For diabetic patients, especially those who are type II diabetics, it is essential that they take the right medicines so that their blood sugar level comes down to suitable limits. Although many of the drugs used in type II diabetes are supposedly having the propensity of decreasing the blood sugar levels, Metformin is good drug in this regards, which doesn’t lead to hypoglycaemic excursions rapidly. In this regards, this drug has become the primary drug of treatment across many patients and are helpful for them in controlling their blood sugar.
The drug from biguanide group is primarily utilized for control of blood sugar in diabetic patients, of the type II variety, because it helps in lowering of the blood sugar levels. It is given in patients having a higher body mass index or those who are obese. It works very well for such patients, because of the insulin resistance that is seen in such types of people. Hence, doctors prescribe such patients this drug to lower the blood sugar, as it works with a unique mechanism of action. It helps in making the muscles and other tissues in the body to utilize glucose in more efficient manner while little insulin presence is necessary. But, unlike secretagogues, this drug doesn’t cause the release of the insulin from the pancreatic beta cells.
Dosage and administration
This drug has been well known among the patients and widely accepted because it can be taken in oral form, without having much side effect. Whenever doctors advise patients to take this biguanide, it is usually started with a minimal dose of 500 mg, especially for the newly detected type II diabetes mellitus cases. Thereafter, as per the control attained, the dose can be titrated gradually so that the drug doesn’t become heavier in dose and still can control the blood sugar level. This is an important way to control the dosage and the doctors can keep a tight check on the diabetes patients. The drug is to be administered after food, unlike other anti-diabetic drugs so that it shows proper control of the blood sugar. If required, the metformin dose can be increased to up to 2000 mg per day, although it doesn’t cause side effects. If the patient control is good with this dose, then it will be beneficial. But, in many cases of type II diabetics, the dosage can be mixed with other anti-diabetic drugs like sulphonylureas or other newer drugs which have come into the market.
Important Precautions
Lactic acidosis is one of the problems found with this kind of drug, belonging to biguanide group, but this drug is having less of this side effect. In cases of renal impairment, hepatic diseases, elderly patients and patients with heart failure should be administered the drug with caution.
Side effects
Since it is a safe drug, it doesn’t have many side effects, but still it should be used carefully in patients. Any kind of hypersensitivity to the drug should be an indication for withdrawal of the drug. Sometimes, side effects like nausea, vomiting, gastric upset and metallic taste have been found with the drug, but these are not serious side effects and subside after use for a few days.

Rated: 4.2 / 5 based on 4.2 customer reviews.

Posted by Pendleton on Jan 28, 2019 Verified Purchase

I reviewed the wrong product - this is the one I don't like

This product hurt my stomach. And, it didn't seem to lower my blood sugar as well either. Unfortunately, I purchased a lot, so I am not sure what to do about that. They usually work with me though, so I will order the ones I got last time. Good company, but I just didn't do well with this product.

Note: does not imply any medical claims from this review.
Posted by liddle on Nov 4, 2018 Verified Purchase


Great service from this company. Delivery was surprisingly quick. Product was exactly as described.

Note: does not imply any medical claims from this review.
Posted by Dr J on Feb 28, 2017 Verified Purchase

metformin safety and efficacy

Metformin has been in the news for being beneficial to diabetics AS WELL AS NONDIABETICS. Metformin reduces insulin secretion by reducing glucose from all dietary sources and this inevitably causes weight loss. Studies show that metformin increases human longevity for this reason. Read peer-reviewed scientific literature to confirm this ( This drug is potent, inexpensive, and a proper "supplement" for anyone knowledgeable and who cares about long-term health. The prices offered here are the lowest online. The product is real and shipping is fast.

Note: does not imply any medical claims from this review. Dear Dr. J, Thank you for your feedback we greatly appreciate it,Please continue supporting us as we value your business with us. thank you
Posted by Dr J on Feb 12, 2016 Verified Purchase

metformin should be put in the water supply

The latest science shows that metformin has been discovered to have more than traditional uses for controlling diabetes. Science shows that the lowered glucose is good for the body...forever. I will probably never stop taking this. It STOPS overeating (you cannot!) and it keeps glucose low, which stops mid-day hunger. The only side effects are diarrhea with a stupidly high-carb/sugar meal. So, you are really being punished for being an have no business eating that poptart anyway.

Note: does not imply any medical claims from this review.

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