Repaglinide - Generic of Pradin

Repaglinide is the generic form of Prandin. It is used to treat those with type 2 diabetes; it reduces blood sugar levels in patients by causing the pancreas to produce insulin. Prandin is sometimes prescribed in conjunction with Glucophage, another diabetes drug. The high glucose levels found in diabetes has increased risk of the following: kidney failure, blindness and loss of sensation. Repaglinide can help to control the glucose levels in diabetics. Unlike most medications, there is no fixed dosage for the management of type 2 diabetes when using Prandin. The dose strength of Repaglinide ranges from 0.5 mg to 4 mg taken with meals. The maximum allowable daily dosage is 16 mg. A patient’s blood glucose is monitored so that only the minimum effective dosage is used. The starting dose for a patient just diagnosed with type 2 diabetes and having a HbA1c result of less than 8% is 0.5 mg with each meal. For patients who have been on blood glucose-lowering drugs and whose HbA1c result is greater than or equal to 8%, the initial dose will either be 1 or 2 mg with each meal. Periodic testing allow for the physician to determine if the dosage is working correctly or needs to be adjusted. After one week, the physician can review the blood glucose readings to see if they are in the good range. Every three months, HbA1c are reviewed for long-term efficiency. If it is found that the use of Repaglinide is not achieving the desired result, metformin or a thiazolidinedione may be added to the course of treatment. There are special dosage instructions for Repaglinide. It should be taken shortly before a meal, 30 minutes or less before mealtime. Prandin can be taken 2, 3, or 4 times a day depending on the numbers of meals you normally eat. If a dose is missed, just take a dose right before the next meal. Do not take 2 doses at once. Your physician should monitor patients taking Prandin and should give a glycosylated hemoglobin test to measure long-term glucose control. The side effects reported from the use of Repaglinide are as follows: allergic reaction, hives, difficulty breathing, swelling of your face, lips, tongue or throat, seizures, jaundice, or chest pain. Less common side effects of Repaglinide include: back pain, bronchitis, chest pain, constipation, diarrhea, headache, indigestion, joint pain, low blood sugar, nasal inflammation, nausea, sinus inflammation, skin tingling, upper respiratory tract infection, urinary tract infection, vomiting, and tooth problems. ; Repaglinide is contraindicated with those with liver problems and should not be taken by patient with type 1 diabetes or have diabetic ketoacidosis. There is a possible food and drug interactions when taking Prandin and the following: airway-opening medication such as Alupent and Ventolin, alcohol, aspirin, barbiturates, beta blockers, blood thinners, blood pressure medications, Carbamazepine, Chloramphenicol, Erthromycin, estrogens, Ketoconazole, Furosemide, glucose lowering agents, Isoniazid, major tranquilizers, MAO inhibitors, Niacin, nosteroidal anti-inflammatory drugs such as Advil or Naprosyn, oral contraceptives, Phenytoin, Probenecid, Rifampin, steroids such as prednisone, sulfa drugs, thyroid medication or water pills. It is not recommended for pregnant or nursing mothers due to unknown risk to the infant.

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