Stalevo is used for the treatment of parkinson's disease. Stalevo works to control the chemical and neurotransmitter imbalance in the brain that causes Parkinson's.


Levodopa/ Carbidopa/ Entacapone



Novartis, Orion Pharma


Levodopa 50 mg / Carbidopa 12.5 mg / Entacapone 200 mg, Levodopa 75 mg / Carbidopa 18.75 mg / Entacapone 200 mg, Levodopa 100 mg / Carbidopa 25 mg / Entacapone 200 mg, Levodopa 150 mg / Carbidopa 37.5 mg / Entacapone 200 mg

India, Turkey

Out of Stock.



Background and development of Stalevo

Stalevo has emerged as a medication in the field of neurological therapeutics. Through research and rigorous testing, it has been discovered to be highly effective in treating specific dysfunctions of the neurons. The creation of Stalevo can be credited to an approach that combines various ingredients, offering patients a more holistic treatment solution.

Importance in the medical field

In the realm of terminology today, Stalevo holds a crucial position. With Parkinsons' disease and other related conditions impacting several individuals, there is an urgent need for effective treatments. Stalevo offers a practical treatment option and demonstrates the remarkable progress made in pharmaceutical innovations.


Primary indications for Stalevo

Stalevo is a prescription medication that is mainly used for managing Parkinson’s disease, as well as treating neurodegenerative disorders characterized by symptoms of stiffness and lack of movement. It is also prescribed for conditions that show a deficiency in dopamine levels 12.

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Benefits and effectiveness in patients

Stalevo has gained a lot of attention due to its effectiveness. People who take Stalevo often mention experiencing the following benefits; improved motor functions, reduced tremors and stiffness, and a better quality of life.

How it Works

Mechanism of action

Stalevo works by increasing the levels of dopamine in the brain, which helps improve communication. It does this by blocking enzymes that break down dopamine leading to longer-lasting and stronger signals, between neurons.

The active components and their role in treatment

Stalevos strength comes from its three components: Levodopa, which helps produce dopamine. Carbidopa reduces the conversion of levodopa outside the nervous system, thus maximizing its effects on the central nervous system. On the other hand, Entacapone is an effective inhibitor of COMT and ensures a continuous supply of dopamine.

Off-label Use

Common off-label applications

Stalevo is a prescription medication that is primarily used for managing Parkinson’s disease, as well as treating neurodegenerative disorders characterized by symptoms of stiffness and lack of movement. It is also prescribed for conditions that show a deficiency in dopamine levels 12.

Stalevo is sometimes prescribed “off-label” to treat other medical conditions, such as hives or chronic obstructive pulmonary disorder (COPD) 3.

1Medical News Today

Clinical studies and patient outcomes in off-label scenarios

There have been cases in clinical reports where Stalevo has shown effectiveness in unconventional uses. Research suggests it can improve sleep patterns in patients with Restless Leg Syndrome and alleviate medication-induced parkinsonism. However, conducting clinical evaluations before making broad conclusions based on these findings is crucial.

Side Effects

Overview of potential side effects

Similar, to any medication Stalevo does have some potential side effects. Although most people may experience symptoms, there is a possibility that specific individuals could have more severe reactions.

Factors influencing side effect severity and occurrence

The occurrence and intensity of side effects may vary depending on factors such as metabolic differences, other medications taken simultaneously, existing health conditions, and variations in dosage.

Common Side Effects

List and description of the most frequent side effects

Patients may encounter a range of symptoms, including muscle movements known as dyskinesia, nausea and vomiting, dizziness upon standing up orthostatic hypotension, and difficulties with sleep, like insomnia or disturbances in their sleep patterns.

Management and mitigation strategies

It is essential to take an approach to manage the side effects effectively. This includes adjusting the dosage with the guidance of a healthcare professional, using medications to alleviate any feelings of nausea, and regularly monitoring the patient's condition while providing them with education and information.

Dosage and Administration

The ideal dosage measurement always depends on how severe the ailment's factors related to the patient. For Parkinsons' disease, the dosage is optimized by considering symptom relief and potential side effects. In cases where medications are used for off-label conditions, a cautious approach is taken with adjustments, often beginning with lower doses.

Proper administration techniques and timings

To ensure the medication works effectively, following these guidelines is essential: 1. Take the medicine by mouth with plenty of water. 2. Avoid eating before or after taking the medication. 3. Stick to a schedule for taking your doses. These steps will help ensure that you get the results from your medication.


Ingredients and their roles

Stalevo, a composite formulation, boasts:

  • Levodopa: Dopamine precursor
  • Carbidopa: Peripheral decarboxylase inhibitor
  • Entacapone: COMT inhibitor

Potential allergens or inactive ingredients

Stalevos' main components play a role in its therapeutic effects, but it's essential to consider the additional ingredients that could potentially cause hypersensitivity reactions in susceptible individuals. It is advisable to refer to the medication insert for a comprehensive list of all the components included.


Ideal conditions for storing Stalevo

Stalevo, as a crafted pharmaceutical product, requires specific storage conditions. It is essential to keep it in an environment with a temperature between 15 and 30 degrees Celsius. Additionally, it should be stored in a place where there is no moisture, so it's not recommended to keep it in places, like bathrooms.

Expiration and the importance of proper storage

The expiration date of medication is more than a number. It represents the period during which the drug maintains its effectiveness for treatment. Properly storing Stalevo in certain conditions helps to keep its chemical components unchanged. Inadequate storage can speed up the deterioration process, which may lead to reduced effectiveness or unexpected side effects.


Potential drug-drug interactions with Stalevo

When certain medications are taken together with Stalevo, they can have an effect on its profile. It's essential to be aware of interactions, such, as; Antidepressants; These can increase the risk of serotonin syndrome. Antipsychotics: They may counteract the actions of Stalevo. Taking MAO inhibitors with Stalevo can increase the risk of hypertensive crises.

Food and drink considerations

The absorption of Stalevo may be affected by elements in your diet. For instance, meals that are high in protein can reduce its absorption. It's also essential to avoid or limit alcohol consumption as it can worsen the side effects.


Situations where caution is advised

Although Stalevo provides a solution for conditions, it is essential to be cautious in specific situations. Patients with a medical history of heart problems, stomach ulcers, or seizures should inform their healthcare providers before starting the treatment.

Serious side effects or risks

While it is not common, some people may experience adverse effects. These may include arrhythmias, severe low blood pressure, and symptoms such as hallucinations or paranoia.


Conditions or scenarios where Stalevo should not be used

Certain medical conditions and physical states make it impractical to use Stalevo. These include Having an allergic reaction to any ingredient in Stalevo. Using nonselective MAO inhibitors at the same time. Having untreated narrow-angle glaucoma. Please note that it is essential to consult with a healthcare professional for advice regarding using Stalevo or any other medication.

Alternative treatments in these cases

If Stalevo cannot be used, doctors may consider treatment options. These can include using medications like Pramipexole or Rasagiline or exploring nonmedication approaches such, as physiotherapy or deep brain stimulation.

Careful Administration

Special considerations when administering Stalevo

Administering Stalevo is not a chore. It is crucial to ensure the tablet is whole and not crushed or chewed. Additionally, following a dosing schedule and avoiding sudden discontinuation is vital for achieving the best therapeutic results.

Monitoring and follow-up guidelines

Regular checkups with your doctor, which include discussing any symptoms you may be experiencing and performing tests such as liver function tests, can help prevent complications.

Important Precautions

Safety precautions for patients and caregivers

People taking Stalevo should be informed about the possibility of feeling drowsy. They should avoid driving or operating machinery if they experience this side effect. Caregivers should also stay alert for any changes in mood or potential hallucinations.

What to avoid while on the medication

Besides the alcohol and high-protein diets mentioned earlier, patients should avoid using over-the-counter medications without seeking advice. This is because there may be interactions that could occur.

Administration to Elderly

Age-related considerations in dosage and side effects

Elderly individuals, due to changes in how their bodies process medication, may require adjustments to their dosage. Additionally, they may be more prone to experiencing side effects such as dizziness or confusion.

Monitoring elderly patients on Stalevo

We make sure to monitor and track any adverse reactions along with regularly checking the kidney and liver functions to ensure the safety of older individuals.

Administration to Pregnant Women and Nursing Mothers

Known risks and benefits during pregnancy and lactation

During pregnancy and breastfeeding, changes in the body may affect how Stalevo works. Although there is research on its effects on developing babies, it is advisable to use Stalevo during pregnancy only when absolutely necessary. For breastfeeding mothers, it is essential to be cautious as the drug may pass into breast milk.

Alternatives and precautions during these life stages

It may be worth considering therapeutic approaches, like making lifestyle changes or undergoing physiotherapy during these stages. However, if medication is necessary, it is crucial to ensure monitoring.

Administration to Children

Pediatric dosages and administration guidelines

Due, to the metabolic and developmental characteristics of children, specific dosing regimens are required for the pediatric group. Although Stalevo is not commonly used in children, any administration should be carefully supervised by professionals.

Potential risks and benefits in pediatric patients

It is crucial to assess the balance between risks and benefits, considering the limited availability of comprehensive data for children. Although confident children may experience relief from symptoms, it is essential to remain attentive to side effects.


Symptoms of Stalevo overdose

In the case of taking much medication, it could lead to a variety of symptoms such as irregular heartbeats, severe drop in blood pressure, and difficulty in breathing.

Immediate actions and treatment recommendations

If there is a suspected overdose, it is essential to seek medical help. This may involve procedures like lavage or the use of activated charcoal.

Handling Precautions

Safe handling, disposal, and storage measures

The Stalevo tablets must be removed from their packaging before you take them. Make sure to dispose of any unused medication properly without throwing them in the sink or household trash.

Protecting oneself and the environment

To prevent consumption by children or pets, it is essential to store Stalevo in a place that is not easily accessible. When disposing of Stalevo, it is better to opt for pharmacy-driven disposal programs by throwing it away in regular waste to protect the environment.

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