Generic Casodex, Bicalutamide

Bicalutamide is an antiandrogen prescribed in the treatment of prostate cancer.

Casodex

Bicalutamide

Calutide

10, 28

Cipla, Winthrop, Actavis

Tablet

50mg, 150mg

India

Bicalutamide

Uses
Bicalutamide is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) in the treatment of metastatic prostate cancer (cancer that started in the prostate and can or has already spread to other parts of the body).
How it Works
Bicalutamide is an anti-androgen, in porstate cancer, the cancer cells need the male hormone(Testosterone) to grow and multiply, Bicalutamide blocks the actions of male sex hormones called androgens and it also reduces the amount of male hormones (such as testosterone) that the body produces this directly blocking the effect of testosterone on prostate cancer cells. This causes the cancer cell growth to slow down and stop it from spreading.
Common Side effects
Patients who take Bicalutamide may suffer from such side effects; Rash, Dizziness, Decreased libido, Cough, Constipation, Breast enlargement in male, Sleepiness, Weakness, Nausea, Abdominal pain, Bone, back, or pelvic pain Dyspepsia, Weight gain, Increased liver enzymes, Breast tenderness, Anemia, Depression, Decreased appetite, Flatulence, Constipation, Hot flashes
Introduction
Bicalutamide is used in the treatment of Prostate cancer. Prostate cancer starts in the prostate gland of males and rapidly spreads to other parts of the body. This tablet is to be consumed orally. The consumption of this tablet results in the blocking of the effects of male hormone known as Androgen and inhibits the growth of cancer cells in the body. It is considered to be a standard medicine in the treatment of prostate cancer.
Use
Bicalutamide is a tablet which needs to be consumed orally. Initially, it should be taken along with the lutenizing hormone injection. It is important to consult a doctor prior to the consumption of the tablet. It is recommended to take this tablet with an empty stomach once in the morning or in the evening and the same must be followed everyday without any change in the timings. Lutenizing hormone injection along with the tablet inhibit the growth of prostate cancer cells and help cure the patient.
Dosage and administration
A doctor will prescribe the dosage of this tablet to the patient depending on the stage of prostate cancer. The standard dosage is 50 mg and the same should be continued every day. In case the patient misses a dosage, it is advisable not to take 2 doses of the medicine on the next day. It is better to skip the dose and continue the regular routine the next day.
Warning
It is important to let the doctor know if the patient is suffering from any form of allergy.Inform the doctor about any liver ailments or any other medication that the patient is taking for liver disease.This drug is used only for prostate cancer, which occurs only in men. It should not be taken by pregnant women under any circumstances.Do not consume any form of alcohol while on medication.This tablet makes your skin very sensitive and you can get sunburned very easily. Try to avoid the sun as much as possible.Using this drug is not advisable for patients suffering from diabetes as it can increase the levels of blood sugar in the body thus resulting in drowsiness, faster breathing rate, etc.
Side effects
Using this tablet for the treatment of prostate cancer has many side effects such as: Severe pain in the pelvic, back, and bones.Muscle fatigue and weakness.High blood pressure.Swelling is observed on hands, ankles, and/or feet that result in severe pain.Nausea, vomiting and diarrhoea.Abnormal hair loss.Loss of weight and appetite.Difficulty sleeping.Urinating frequently.Formation of rashes on the body.Chest pain.Yellowing of the eyes.

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