Crotamiton Cream is a nonsteroidal topical agent prescribed for itchy and irritated skin that is caused by a range of factors, such as eczema, insect bites, allergic reactions, scabies, etc.

Generic Eurax




Primal Healthcare, Abbott





I. Introduction

Brief Overview of Crotamiton

Crotamiton is a type of cream or ointment that is commonly used to help relieve skin irritations. It is particularly effective in treating conditions like scabies and itching.

Medical Conditions it Treats

The medicine is often prescribed for scabies, a skin infection caused by mites, as well as pruritus, which is also referred to as itching.

Importance of Informed Usage

A thorough knowledge of how Crotamiton works in the body, its potential side effects, and how it interacts with substances is crucial for effective and safe treatment.

II. What is Crotamiton?

Chemical Composition

Crotamiton has the formula C13H17NO. It is a substance known for having a hydroxyl and an amine group.

Classification of Drug

This specific medication belongs to the category. It can both combat ectoparasites and relieve itching sensations.

Regulatory Approval Status

Crotamiton has received approval from agencies such as the U.S. Food and Drug Administration (FDA) for treating certain skin conditions.

III. Uses of Crotamiton

Approved Uses

Treatment of Scabies

Scabies is a skin infestation caused by the mite Sarcoptes scabiei. The two most widely used treatments for scabies are permethrin cream and malathion lotion, both of which contain insecticides that kill the scabies mite 1According to a review article published in the Journal of Parasitic Diseases, other effective treatments for scabies include benzyl benzoate, crotamiton, ivermectin, and sulfur ointment 2.

Learn more:

Management of Pruritus

Crotamiton is an antipruritic medication used to relieve itching and skin irritation caused by skin conditions such as itchy dermatitis and allergic rashes 12. According to DrugBank Online, crotamiton relieves itching by producing a counter-irritation. As crotamiton evaporates from the skin, it produces a cooling effect that helps to divert your body’s attention away from the itching 1.

Learn more:

Off-label Uses

Potential for Eczema Relief

Crotamiton is an antipruritic medication that relieves itching and skin irritation caused by skin conditions such as itchy dermatitis and allergic rashes. While there is no endorsement, some anecdotal accounts and smaller clinical studies indicate that crotamiton may positively impact managing the symptoms of eczema.

Learn more:

Role in Alleviating Dermatitis

Crotamiton is a medication that can relieve dermatitis, a broad term used to describe skin inflammation 1It is usually used to treat pruritus (itching of the skin) caused by scabies or sunburn 2Crotamiton works by killing the mites that cause scabies and also helps relieve itching related to scabies and other skin conditions 1It belongs to two classes of drugs: scabicides and antipruritics 1.

Learn more:

IV. How Crotamiton Works

Mechanism of Action

Crotamiton works by altering the function of acetylcholine, a neurotransmitter that plays a role in skin perception.

Interaction with Skin Cells

It creates a combination with the cells of the skin keratinocytes, influencing how they react to irritating triggers.

Role in Neurotransmission

Crotamiton works by interacting with the nerves, which helps to reduce itching by affecting neurotransmission.

Duration of Effectiveness

The therapeutic effects of this treatment typically last for 6 to 10 hours after it has been applied.

V. Dosage and Administration

For Adults

The typical approach is usually to apply the solution twice a day.

For Children

For patients, it is important to adjust the dosage and typically administer it once a day under the supervision of a medical professional.

Route of Administration

Topical Application Guidelines

You'll want to apply the medication across the areas that are affected.

How to Administer

Pre-application Precautions

It is advisable to cleanse the skin before applying anything to it.

Post-application Care

Try to avoid contact with any type of fabric that could potentially absorb the medication.

VI. Composition of Crotamiton

Active Ingredients

Crotamiton, as the ingredient, makes up a certain proportion of the overall volume.

Inactive Ingredients

Used additives include substances like propylene glycol and ethyl alcohol.

Available Formulations (Cream, Lotion)

You can find the drug in forms, such as creams and lotions.

VII. Side Effects

Common Side Effects

Skin Irritation

Redness and mild irritation are customary.

Mild Burning Sensation

It's common to experience a harmless burning sensation after applying the product.

Rare but Severe Side Effects

Allergic Reactions

Allergic reactions that trigger anaphylaxis, although uncommon, require urgent medical attention.

Symptoms of Overdose

Using much of this product could lead to toxicity in the body.

VIII. Interactions

Drug Interactions

Risk with Topical Steroids

Corticosteroids have the potential to make the skin thinner, which can become risky when used in combination with Crotamiton.

Combining with Antihistamines

Using antihistamines concurrently requires monitoring as there may be potential interactions.

Food and Lifestyle Interactions

During your treatment with Crotamiton, you should refrain from using alcohol or other substances that may irritate the skin. By understanding Crotamiton, both patients and healthcare providers can actively participate in a more knowledgeable and, therefore, safer and more effective therapeutic journey.

IX. Warnings and Contraindications

General Warnings

It is essential to be familiar with the contraindications and precautions of Crotamiton when using it. Ignoring these warnings could lead to effective treatment or unwanted side effects.



Crotamiton should be avoided by individuals who have a hypersensitivity, to the drug or any of its components, as it may lead to an allergic reaction.

Open Wounds and Infections

It is advised to avoid applying the product on wounds or infected skin areas as it may worsen these conditions.

X. Careful Administration and Important Precautions

In Case of Preexisting Skin Conditions

If you have any existing skin conditions, it's best to consult with a healthcare professional, for advice.

Monitoring of Side Effects

It is essential to monitor for any potential side effects, such as redness and itching to evaluate whether the drug is still appropriate, for ongoing use.

When to Stop Use and Consult a Physician

If you experience itching or a rash signs of an allergic reaction or if your symptoms persist beyond a certain period, please stop using the product and seek immediate medical attention.

XI. Special Populations

Administration to Elderly

Adjustments in Dosage

It might be necessary to consider adjusting the dosage for elderly individuals due to the possibility of reduced metabolic clearance.

Risk of Skin Thinning

Be careful when dealing with this group of people as they are more prone to having thin skin.

Administration to Pregnant Women and Nursing Mothers

Safety Profile

The full effects of Crotamiton, on development are not yet wholly understood, so it is recommended to only use this medication if absolutely necessary.

Alternatives if Needed

Evaluating the potential risks and benefits before proceeding while also exploring alternative treatment options is essential.

Administration to Children

Age-specific Dosage

When prescribing medication for children, it is crucial to calculate the dosage by taking into account their body weight and surface area.

Pediatric Safety Guidelines

Before giving it, make sure to conduct studies, on children to ensure its safety and effectiveness.

XII. Overdose Management

Symptoms of Overdose

Common symptoms that can be observed include feelings of nausea, episodes of vomiting, and the possibility of experiencing nervous system depression.

Emergency Procedures

If someone overdoses, it is crucial to seek medical help. This may involve procedures like lavage.

Long-term Consequences

Excessive drug intake can lead to harm to the liver as well as other potential complications throughout the body.

XIII. Storage and Handling Precautions

Ideal Storage Conditions

Keep Crotamiton stored in a sealed container at average room temperature, ensuring it is shielded from dampness and direct exposure to sunlight.

Expiry and Disposal Guidelines

Make sure to adhere to the expiration date of the medication and follow the local guidelines for appropriate disposal.

XIV. Conclusion

Summary of Key Points

The article aims to provide an overview of Crotamiton, covering its pharmacological characteristics, contraindications, and specific populations where it is used.

Importance of Consulting with Healthcare Providers for Personalized Medical Advice

It is highly recommended to consult with healthcare professionals to receive medical advice, for accurate diagnosis and suitable treatment. By following these guidelines you can maximize the effectiveness of Crotamiton while minimizing any risks.

Customers also bought

Popular Products

Similar Product