Lidocaine Spray

Lidocaine Spray is a local anesthetic that is used to temporarily numb areas, helping to prevent discomfort or pain during certain medical examinations or procedures.

Xylocaine Spray


Lox Spray, others


Neon Pharma and others




Lidocaine Spray


During the middle of the century, there was a significant advancement in local anesthetics when Lidocaine was synthesized. This versatile medication, initially developed in 1943, has proven to be enduring. Lidocaine falls into the category of local drugs, setting it apart from esters, which make up another primary class of local anesthetics. Being a compound, Lidocaine is known for its lower allergenicity and overall stability making it suitable for a wide range of medical applications.

Uses of Lidocaine Spray

Lidocaine Spray is a medical tool primarily used as a topical anesthetic. Its spray formulation makes it easy to apply directly, providing convenience.

Here are some of its uses3;

1. Numbing the Surface; Lidocaine Spray is commonly used to numb the skin and mucous membranes, making it valuable in dental procedures.

2. Relieving Pain from Minor Burns or Cuts; The acting analgesic properties of Lidocaine make it a popular choice for immediate relief from discomfort caused by minor skin injuries.

3. Numbing Agent for Medical Tests or Procedures; Doctors often utilize Lidocaine Spray to numb areas of the body before performing minor surgical procedures, biopsies, or catheter insertions. This helps reduce discomfort during such operations.

The precise and targeted relief provided by Lidocaine Spray is highly valued in clinical settings as it ensures patient comfort while enhancing procedure efficiency.


How it Works

Lidocaine plays a role as a sodium channel blocker, which is the key to its success as a local anesthetic2. Let's dive deeper into this;

  • Mechanism of Action on Nerve Cells; Lidocaine works by inhibiting the movement of ions needed for nerve cell impulses. It specifically blocks the sodium channels on the membrane of nerve cells. Blocking these channels prevents sodium ions from entering the nerve cell during depolarization. As a result, it stabilizes the nerve's action potentials. Raises the threshold for electrical excitation. This means that it reduces the likelihood of nerve firing leading to decreased pain sensation in the area where Lidocaine is applied.
  • Duration of Numbing Effect; Typically, Lidocaine starts numbing within minutes after application. The anesthesia usually lasts 1-2 hours, although this may vary depending on factors such as the formulation of Lidocaine, the dosage administered, and individual patient characteristics.

    Lidocaine's effectiveness and safety profile, and ability to act quickly in localized areas continue to make it an invaluable tool for healthcare providers worldwide.


Dosage and Administration

Lidocaine Spray is highly regarded for its accuracy and versatility in providing targeted pain relief. It is crucial for both healthcare professionals and patients to adhere to the recommended dosing guidelines to ensure therapeutic effects and patient safety2.

The recommended dosages for applications:

  • For minor burns or cuts; Apply a small amount, usually 1 or 2 sprays, directly to the affected area.
  • For anesthesia; Healthcare professionals may apply a more significant quantity based on the specific procedure and the patient's health condition.
  • For mucosal application; Normally 1-3 sprays are used, but it is essential not to exceed the maximum limit mentioned in the product instructions.

The Effectiveness:

  • The skin is clean and free from excessive oil or lotion before applying the spray.
  • Apply an even layer of spray, to the desired area.
  • It is advisable to avoid overspray and refrain from applying it on open wounds or damaged skin unless guided by a healthcare professional.

    Before starting to use Lidocaine Spray consulting with a healthcare professional is of important. Additionally, strictly following the instructions provided on the product label is essential.



The Lidocaine Spray is carefully formulated to provide targeted relief. It contains inactive components that contribute to its effectiveness and stability.

  • Active Ingredients; The main active ingredient in the spray is Lidocaine, which's a local anesthetic that works by blocking sodium channels.
  • Inactive Ingredients; These can include propellants, preservatives, and stabilizers such as ethanol, polyethylene glycol, and hydrofluorocarbon propellant.
  • Different. Formulas; Lidocaine Sprays are available in concentrations, with 4% and 10% being the most common options. The choice of strength depends on the intended use and the patient's requirements.

    It is recommended that patients who have known sensitivities or allergies carefully review the ingredients listed on the product label and consult with their healthcare professional if necessary.


Side Effects

While Lidocaine Spray is generally well tolerated and praised for its safety record, it has possible side effects like any intervention1. Here's a summary;

  • Irritation or redness at the site of application
  • Tingling or itching
  • Unusual sensations of warmth or coldness
  • More severe effects may occur in rare cases, such as an irregular heartbeat, difficulty breathing, or seizures. However, these are typically seen when there is an overdose or absorption into the bloodstream.

    Patients should be advised to discontinue use and consult a healthcare professional if they experience persistent adverse reactions after applying Lidocaine Spray. In conclusion, Lidocaine Spray plays a role in local anesthetics. Its effectiveness, versatility, and overall favorable safety profile speak for themselves. Nevertheless, it's essential to be mindful of side effects by following dosing guidelines responsibly and educating patients about its proper use.


Common Side Effects

Lidocaine Spray is a tool for managing pain, but it's essential to be aware of potential side effects. While most of these effects are localized and temporary, it's crucial to acknowledge them;

  • Tingling or Itching at the Application Site; Some patients may experience a tingling or itching sensation after using the spray. This usually goes away as the numbing effect kicks in.
  • Redness or Swelling; In some cases, there may be redness or swelling at the application site, but it typically resolves independently.
  • Rare Side Effects to Be Aware of; Although uncommon, there have been isolated instances where Lidocaine is absorbed into the bloodstream resulting in severe effects like irregular heartbeat, difficulty breathing, or seizures.

    These occurrences underscore the importance of following dosing instructions. If patients experience persistent side effects, they must promptly consult a healthcare professional.


Off-label Use

Medical professionals often devise ways to use well-established medications, and Lidocaine Spray is a prime example. In addition to its approved use as an anesthetic, it has also been effective in treating certain chronic pain conditions like neuropathic pain and complex regional pain syndrome. While some emerging research suggests benefits in these alternative applications, it's important to note that the safety and effectiveness of such uses haven't been extensively studied in large-scale clinical trials. Therefore, consulting with a healthcare professional is crucial when considering these off-label uses. When exploring off-label use, discussing with a healthcare professional who can evaluate the potential risks and benefits is essential.



Like any medication, Lidocaine Spray can have interactions with other substances. Some drugs and substances may interfere with Lidocaine Spray, such as anti-arrhythmic drugs like procainamide and amiodarone and other local anesthetics. It's important to note that substances that reduce liver metabolism, like cimetidine, can enhance the effects of Lidocaine. To avoid interactions, it is crucial to maintain open communication with your healthcare provider.

Make sure to provide them with a list of all the medications, supplements, and herbal products you are taking. This will allow your provider to anticipate interactions and adjust your treatment plan accordingly. To ensure the use of Lidocaine Spray, it is essential to understand potential drug interactions and actively manage them through patient education and professional guidance.

In conclusion, Lidocaine Spray remains a valuable tool in managing various pain-related conditions. Its convenience, effectiveness, and documented safety profile make it an essential part of modern medicine. However, like any medication, it should be used responsibly with informed decision-making to maximize its benefits while minimizing potential risks.


Warning and Contraindication

While Lidocaine Spray has established itself as an effective local anesthetic, there are certain medical situations where its use is not recommended. It is essential to consider its application, especially in specific medical conditions;

  • Allergic Reactions; If you have a known allergy to Lidocaine or similar anesthetic agents, it is advised to refrain from using this spray.
  • Inflamed Skin; Applying the spray on open wounds or highly inflamed skin can result in excessive absorption of Lidocaine into the bloodstream.
  • Specific Medical Conditions; Patients with liver disease, heart block, or low blood levels of pseudocholinesterase protein may need to avoid using Lidocaine.

    Please note that this list does not cover all scenarios, so it is crucial to consult with a healthcare professional before considering using Lidocaine Spray.


Careful Administration

Efficient utilization of Lidocaine Spray goes beyond applying it; it also involves being vigilant during and after its usage. When administering this anesthetic, it is crucial to adhere to safety protocols strictly. Continuously monitoring for adverse reactions such as increasing redness or swelling is paramount. During the application process, it is essential to ensure that the spray does not come into contact with the eyes and to use the product in a ventilated area. These are safety measures that should be followed. The cornerstone of administering Lidocaine Spray effectively and safely lies in the application and close monitoring.


Important Precautions

Lidocaine Spray is generally safe to use. It still requires careful consideration and vigilance. There are conditions and warning signs that should be taken into account;

  • Precautions for Pre-existing Conditions; If you have any existing heart, liver, or kidney issues, seizures, or respiratory problems, it's essential to discuss with your healthcare provider before using Lidocaine Spray.
  • Signs to Be Aware of After Applying; After applying the spray, it's crucial to watch for any signs of toxicity like dizziness, blurred vision, tremors, or unusual sensations around the mouth.

    Following these precautions may seem strict. They reflect the thorough care healthcare professionals recommend when using topical and local medications like Lidocaine Spray.

    Lidocaine Spray remains an option for local anesthesia due to its intense pain-relieving effects. However, it's essential to approach its use with a cautious mindset. From contraindications that warrant avoidance to administration protocols and necessary precautions emphasizing individualized care—using Lidocaine Spray responsibly ensures its optimal effectiveness. As with any medication, it is essential to consult with healthcare before using Lidocaine Spray. This will ensure that its usage is safe, effective, and specifically suited to the health needs of each patient.


Administration to Specific Populations

When administering Lidocaine Spray, factors specific to each patient play a role. This is particularly important in populations where careful usage is not just recommended but necessary.

Elderly: Special Precautions and Dosage Considerations

Elderly individuals might experience heightened sensitivity to Lidocaine, which could necessitate initial dosages. It is crucial to monitor for any signs of toxicity, considering the possible decline in liver and kidney function associated with aging. Taking care is essential to prevent worsening existing cardiac conditions among this particular age group.

Pregnant Women and Nursing Mothers: Safety Profile and Recommendations

Lidocaine falls into the FDA Pregnancy Category B, which means there is no evidence of risk for humans. However, it's still important to take an approach;

  • Lidocaine should only be used during pregnancy if the benefits outweigh the potential risks to the fetus.
  • Although Lidocaine does pass into breast milk, the amount is usually not significant enough to raise concerns.

    Its recommended to consult with a healthcare professional for guidance.

Children: Age-Appropriate Dosing and Potential Risks

When giving medication to children, it's essential to customize the dosage based on their body weight. It's crucial to be careful and avoid ingestion or applying the medicine on large areas of their skin. Following the dosage guidelines strictly is necessary because there is a risk of the drug being absorbed into their system.



It is essential to store Lidocaine Spray to maintain its effectiveness and safety.

  • Recommended storage conditions; store it at room temperature, away from heat and cold. Avoid freezing the spray.
  • Shelf-life and Expiration Considerations: Do not use the spray beyond its expiration date to ensure its quality. It is also essential to check the packaging to ensure its integrity.



When excessive amounts of Lidocaine Spray are used, there is an increased risk of experiencing toxicity. In some cases, it is crucial to take immediate and decisive action. Symptoms of an overdose may include seizures, drowsiness, slowed breathing, loss of consciousness, and irregular heartbeat. If you suspect an overdose, contacting emergency services or a poison control center for prompt medical assistance is essential. Quick attention from professionals is vital in these situations.


Handling Precautions

Like any medication, handling Lidocaine Spray with care is essential due to its potential to heal and harm if misused.

  • To ensure handling and disposal, promptly and securely replace the cap after use. Dispose of expired containers following local regulations.
  • To prevent contamination or misuse, avoid sharing the spray with others and be cautious not to spray it near the eyes or mouth to prevent absorption.

    In summary, Lidocaine Spray is a regarded local anesthetic that significantly benefits managing painful conditions. However, using it responsibly involves considerations. From administering it to storing, handling, and using it carefully, every interaction with this medication is an opportunity to maximize its advantages while minimizing risks. This responsibility becomes more important for special populations such as elderly pregnant women, nursing mothers, and children with unique needs. Ultimately this underscores the medical principle of prioritizing patient safety—do no harm—which applies to all medications, including Lidocaine Spray.

Rated: 5.0 / 5 based on 5.0 customer reviews.

Posted by Hall on May 18, 2023 Verified Purchase


joint pain relief

Note: does not imply any medical claims from this review.
Posted by Carr on Nov 27, 2021 Verified Purchase

Lidocaine 10% is the best

We use this spray extensively for suturing. It works fast, is easily re-applied if needed, and in almost every case it eliminates the need for injecting any lidocaine. It is also indispensible for numbing the cervix to ease IUD insertions. This is one item that we never want to be without, thank you for keeping it in stock!

Note: does not imply any medical claims from this review.
Posted by Carr on Apr 19, 2020 Verified Purchase


Very effective for easing the discomfort of IUD inserts, and ideal for repairs of childbirth lacerations without needing to draw up and inject lidocaine which can cause swelling.

Note: does not imply any medical claims from this review.
Posted by JD on Feb 18, 2020 Verified Purchase

Good product

This item works great.  I have had good results with all Neon pharma products.

Note: does not imply any medical claims from this review.
Posted by Carr on Dec 27, 2019 Verified Purchase

Excellent Value

The 10% Lidocaine Spray is sometimes difficult to find, out of stock, or not reasonably priced - but not here! This product is critical for doing difficult IUD inserts, and this is the only supplier I can rely on to always have it when we need to re-order. Thank you!

Note: does not imply any medical claims from this review.
Posted by Prince on May 10, 2019 Verified Purchase

Great pain relief.

My sister uses this for severe back pain.This allows a full night’s sleep. OTC lanocaine sold in US is just not strong enough.

Note: does not imply any medical claims from this review.
Posted by AK on Jan 21, 2019 Verified Purchase

Well done!

Works well to numb injection sites!

Note: does not imply any medical claims from this review.
Posted by Carr on Jul 8, 2018 Verified Purchase

Great price

This product is sometimes hard to find in stock, or very over priced when it is available. Your price was excellent, product available, and shipping time was good. Thank you! We will buy from you again.

Note: does not imply any medical claims from this review.
Posted by Martinez on Jun 30, 2018 Verified Purchase


Very happy with the quality and performance of this specific product. I highly recommend it.

Note: does not imply any medical claims from this review.
Posted by Hogman on Mar 14, 2018 Verified Purchase

Fine product

Use this regularly and I enjoy using it. Was packaged very well.

Note: does not imply any medical claims from this review.
Posted by perlman on Feb 8, 2018 Verified Purchase

very satisfied

product was delivered earlier than promised

Note: does not imply any medical claims from this review.
Posted by Rebecca on Aug 3, 2017 Verified Purchase

This is for my tendonitis, and it worked by numbing the area, I was very happy with this purchase. It came faster than I expected, plus, plus!

I don't think it was packaged really well ,some of the fluid leaked out of one of the bottles, I didn't care, I just think you should know. Great product!

Note: does not imply any medical claims from this review.
Posted by Tom on Feb 16, 2017 Verified Purchase


Better than anything in the stores. Not afraid of getting scratched with this stuff handy.

Our response:
Dear Tom, Thank you for your feedback we greatly appreciate it,We are glad to know you are happy with your purchase, Please continue supporting us as we value your business with us. thank you
Note: does not imply any medical claims from this review.
Posted by Huey on Aug 31, 2016 Verified Purchase

Good stuff

The product is of high quality at very low price. Shipment is quick.

Note: does not imply any medical claims from this review.
Posted by Huey on Jan 10, 2016 Verified Purchase

Very good!

Prompt shipment, quick delivery, and excellent quality. Highly recommend.

Note: does not imply any medical claims from this review.
Posted by Huey on Dec 12, 2015 Verified Purchase

Very good!

Prompt shipment, quick delivery, and excellent quality.

Note: does not imply any medical claims from this review.
Posted by Huey on Nov 17, 2015 Verified Purchase

Excellent service and quality

Robert is an excellent customer service agent. I was able to purchase the items I need. The quality of the purchase and prices are very good. I would place my order again soon.

Note: does not imply any medical claims from this review.
Posted by Huey on Nov 17, 2015 Verified Purchase

Excellent services and quality

Robert is an excellent customer service agent. I was able to purchase the items I need. Very good quality and prices.

Note: does not imply any medical claims from this review.

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