Carbidopa/ Levodopa

Carbidopa/ Levodopa combination drug may be prescribed to help alleviate the symptoms of Parkinson's disease, post-encephalitic parkinsonism, or symptomatic parkinsonism.

Generic Sinemet

Levodopa/ Carbidopa

Syndopa, Syndopa Plus, Syndopa CR


Sun Pharma

Tablet, Tablet (SR)

Levodopa 10 mg / Carbidopa 100 mg, Levodopa 25 mg / Carbidopa 100 mg, Levodopa 25 mg / Levodopa 250 mg, Levodopa 50 mg / Carbidopa 200 mg




Levodopa is used in the treatment of Parkinson's disease or shaking palsy.

How it Works

Levodopa works by improving muscle control. Levodopa is converted to dopamine, a chemical messenger which is needed to control the movement through transmission of signals in the brain. Therefore levodopa allows more normal movements of the body.

Common Side effects

Some of the potential side effects of Levodopa can include the symptoms below;

Loss of appetite,
Orthostatic hypotension,
Movement disorder



Carbidopa is used in the treatment of Parkinson's disease and to relieve its symptoms

How it Works

Carbidopa is always given along with levodopa. Carbidopa works by preventing levodopa from being broken down into dopamine before it reaches the brain. This means more levodopa gets into the brain to be converted into dopamine.This allows for a lower dose of levodopa to be administered, which causes less nausea and vomiting.

Common Side effects

Some of the potential side effects of Carbidopa can include the symptoms below;

Neuroleptic malignant syndrome,
Panic attacks,
Altered behaviour,
Mood changes,
Frequent dreams,
Increased sweating,
Irregular heart rate,
Altered sleep,
Burning sensation of tongue,
Worsening of tremor,
Muscle stiffness.


Levodopa belongs to a class of medication called central nervous system agents. It gets converted to dopamine in the brain. Carbidopa belongs to a class of medication called decarboxylase inhibitors. It works by preventing levodopa from being broken down before it reaches the brain. This allows the effectiveness of a lower dose of levodopa thus causing less nausea and vomiting.

Administration of dopamine alone is ineffective in the treatment of Parkinson's disease because it gets broken down before crossing the blood-brain barrier.


This medication is a combination of Levodopa and Carbidopa. It is used to treat the symptoms of Parkinson's disease and like symptoms that may develop after encephalitis, carbon monoxide poisoning, or manganese poisoning. The symptoms of Parkinson's disease include tremors (shaking), stiffness, and slow movement. This is caused by a lack of dopamine, a naturally occurring substance usually found in the brain.

Dosage and administration

The dosage is based on your medical condition and response to the treatment. Take this medication orally as directed by your doctor, usually 3 to 4 times a day. You can take it with or without food however, taking it with food may help decrease nausea.

It is advised to avoid a high-protein diet since it decreases the amount of levodopa the body takes in, unless instructed otherwise by the doctor. If you are taking any iron supplements, then separate taking them from the hours you take this medication since iron reduces the absorption of the drug in the body.

To reduce the chances of side effects, the doctor may start you off with a low dose of this medication and gradually increase the dose thereafter if deemed necessary. Use this medication regularly as prescribed to get the best results.

This medication comes in a combination of different strengths of carbidopa and levodopa. It is important to have the correct dose for both drugs.


Before being prescribed this medication, inform the doctor of your complete medical history, whether you suffer or have suffered from any liver ailments, kidney disease, diabetes, etc. The doctor would then determine if this medication is right for you.
Inform the doctor if you have any existing or past allergies to any substances as the medication may have such substances in its composition. In case you experience any allergies or discomfort while using this medication, stop using this medication and consult the doctor immediately.
This medication is known to make you dizzy when used, hence you are advised not to drive or operate any machinery after taking this medication.
This drug sometimes has a wearing off syndrome, where there might be the onset of a few symptoms just before the next dose. Consult with your doctor about this.
Do not stop taking the medicine without consulting the doctor otherwise there are chances that the symptoms may return in a more severe form. While discontinuing the use of the drug, gradually taper the dose and do not stop taking it abruptly.

Side effects

Loss of appetite
Turns the color of saliva, urine, and sweat darker

Rated: 5.0 / 5 based on 5.0 customer reviews.

Posted by Robert on Jul 27, 2017 Verified Purchase


I use this a a nootropic and it indeed does the job. Very legitimate medication and professional vendor.

Note: does not imply any medical claims from this review.

Customers also bought

Popular Products

Similar Product