Ciprofloxacin
Uses
Ciprofloxacin is used in the treatment of bacterial infections and tuberculosis (tb).
How it Works
Ciprofloxacin is known as an antibiotic. Ciprofloxacin works by inhibiting the DNA replication which then Kills the bacteria.
Common Side effects
Patients who take Ciprofloxacin may suffer from such side effects;
Nausea,
Diarrhoea,
Rash,
Allergic reaction
Introduction
Ciprofloxacin is the synthetic form of chemotherapeutic antibiotic. Ciprofloxacin belongs to the class of drug known as fluoroquinolone. It is considered as the second generation of fluoroquinolone antibacterial. Ciprofloxacin works by interfering with the action of the enzyme that causes DNA to reverse after copying, which then further stops the DNA and protein synthesis and finally kills the bacteria. There are more than three hundred different brand names of Ciprofloxacin being marketed throughout the world. Some of them are known as Baysip, Ciflox XL, Cipro XR, Ciloxan, Prociflor, Ciproxin, Cipro and the most recent one is Proguin in United States, United Kingdom, and Canada. In Russia and India it is mainly being marketed as Ciprex and in Spain as Cetraxal. Bayer A.G was the first who patented Ciprofloxacin in 1983 and then in 1987 it was approved by FDA (U.S. Food & Drug Administration). There are 12 FDA approved uses of Ciprofloxacin for humans. Ciprofloxacin also has its advantages in veterinary use. It also interacts with thyroid medication and natural and herbal supplementation.
Composition
The main component or ingredient of this drug is CIPROFLOXACIN HYDROCHLORIDE. The reported molecular weight of this substance is 385.8. It is yellowish in colour. It comes in varying strength. Inactive components of this drug are titanium dioxide, magnesium stearate, cornstarch, and crospovidone.
Use
Several infections including diseases of joints and bones, gastroenteritis, endocarditis, cellulitis, infections of respiratory and urinary tracts, prostatischancroid and anthrax are usually treated with Ciprofloxacin. It is not recommended as the first-line antibiotic for the infections of chronic bacterial prostatitis, urinary and lower respiratory tracts. Although, it is recommended as the first line antibiotic to cure acute cystitis in females. Ciprofloxacin is also suggested for different skin infections, infectious diarrhoea and typhoid fever. It can also be used in combination with certain other drugs, such as mixture with metronidazole can be used for internal abdominal complicated infections and also in combination with piperacillin is being used in empirical therapy for feverish neutropenic patients.
Dosage and administration
Ciprofloxacin extended-release and immediate release pills are not the same. Ciprofloxacin extended-release pills must be orally administered once daily. For Urinary Tract uncomplicated Infections dosage of 500 mg is recommended for 3 Days. For complicated Urinary Tract Infection dosage of 1000 mg is recommended for 7-14 Days. For acute Pyelonephritis Uncomplicated infection, dosage of 1000 mg is recommended for 7-14 Days The extended-release Ciprofloxacin tablets must be administered not less than 2 hours or 6 hours later than antacids, sucralfate, VIDEX
Side effects
Some of the side effects that will be experienced while taking Ciprofloxacin are such as diarrhea, dizziness, back pains, nausea, headaches, chest pains and allergic reactions.