Tacroz Ointment

Tacroz Ointment is used for the treatment of eczema, Tacroz Ointment works by weakening the skin's immune system thus decreasing the allergic reaction that is causing the eczema to flare up thus relieving the pain that is caused by it.



Tacroz, Tacroz Forte

10g, 20g

Glenmark Pharma


0.03%, 0.1%


Tacroz Ointment


I. Introduction to Tacroz Ointment

A. Overview of Tacroz as a Dermatological Medication

Tacroz Ointment has become a medication in the field of dermatology, providing much-needed relief for individuals suffering from stubborn skin conditions. Its effectiveness in treating ailments like atopic dermatitis has solidified its reputation and gained the trust of healthcare professionals. Tacroz goes beyond being a treatment; it serves as a symbol of hope for patients striving to improve their quality of life despite ongoing skin issues.

B. The Active Ingredient: Tacrolimus

The essence of Tacroz Ointment lies in its component, Tacrolimus. This powerful ingredient belongs to a group of medications called calcineurin inhibitors and can suppress the immune system reactions on the skin. It is carefully formulated to slow down the processes commonly seen in different types of eczema, offering relief from symptoms and reducing the persistent itchiness and inflammation associated with these conditions.

C. Scope and Importance of the Ointment in Skin Care

The use of Tacroz Ointment in skincare is extensive and significant. It goes beyond managing symptoms; it plays a vital role in maintaining the health of the skin amidst chronic dermatological conditions. Its significance cannot be emphasized enough as it:

  • It helps alleviate the itchiness that patients often experience.
  • Assists in restoring the epidermis to its functioning state.
  • Reduces the need for systemic immunosuppressants, minimizing potential adverse effects on the body.

Moreover, it represents an advancement in dermatological treatment options, meeting the needs of individuals seeking nonsteroidal alternatives.


II. Composition and Formulation of Tacroz Ointment

A. Active Ingredients Breakdown

Tacrolimus, one of the ingredients in Tacroz Ointment, is present in tiny but highly effective amounts. The formulation is carefully designed to have its effects without being absorbed into the body excessively. It balances the line between achieving therapeutic benefits and minimizing potential systemic impact with great care and accuracy.

B. Inactive Components and Their Functions

However, the active ingredient is not the critical component. Tacrolimus is accompanied by a blend of ingredients that serve essential roles.

  • Emollients and protectants create a barrier to safeguard the delicate nature of the skin.
  • Stabilizers ensure that the formulation maintains its potency and consistency over time.
  • Humectants contribute moisture-retaining properties to the ointment, promoting an epidermis.

These constituents are not fillers but play a vital role in shaping the ointment's pharmacodynamic profile and making it acceptable for users.

C. Pharmaceutical Form of Tacroz

Tacroz Ointment comes in a solid emulsion form, specially made for applying on the skin. It has a balanced texture and thickness, makes it easy to apply, and allows it to penetrate the inflamed layers of the skin. The careful formulation ensures not only effective treatment but also encourages patients to use it regularly, which is crucial for managing chronic dermatological conditions.

III. Therapeutic Uses of Tacroz Ointment

A. Primary Indications for Eczema and Atopic Dermatitis

The therapeutic benefits of Tacroz Ointment are closely linked to its purpose of treating eczema and atopic dermatitis. As a cream that helps regulate the system, it plays a crucial role in reducing the chronic and recurring nature of these conditions. Tacroz Ointment has been shown to:

  • Lessen the inflammation that is characteristic of these skin disorders.
  • Alleviate the relentless itching that often troubles those affected, resulting in improved sleep quality.
  • Strengthen the skin's barrier, which reduces water loss through the skin and enhances resistance against irritants.

Furthermore, Tacroz has been recommended as an alternative to corticosteroid treatments. While corticosteroids are effective, they come with risks such as skin thinning and other unwanted effects when used for periods.

B. Effectiveness in Treating Lichen Planus

Tacroz Ointment is effective in treating lichen planus, a type of disorder. Tacrolimus, the component of Tacroz, plays a crucial role in its success by relieving itching and reducing inflammation. Research studies have shown improved lichen planus symptoms, leading to better skin and overall patient health.

C. Usage in Psoriasis Management

Tacroz Ointment has a range of applications, including treating psoriasis, a condition characterized by excessive growth of keratinocytes. This ointment effectively reduces the thickness of the skin. Scales through its unique mechanism of action. Although it is not the treatment method, Tacroz is highly beneficial when used alongside other therapies for psoriasis, particularly in situations where conventional treatments are ineffective or not recommended.


IV. Off-Label Uses of Tacroz Ointment

A. Potential Application in Vitiligo Treatment

Tacroz Ointment has recently been exploring possibilities for treating vitiligo, which causes the loss of melanocytes and can be emotionally and aesthetically burdensome for patients. Tacrolimus, the component of Tacroz, has shown promising results in helping repigmentation, especially in areas such as the face and skin folds. The effectiveness of Tacroz in this standard use is believed to stem not only from its ability to regulate the immune system but also from its potential to stimulate melanocyte activity.

B. Role in Scar Mitigation and Keloids

The bothersome consequences of wound healing, such as scars and keloids, have also been tackled using Tacroz Ointment. It is believed that Tacrolimus, by regulating the response and fibroblast activity, might help reduce the visibility of scars. Informal reports and initial studies indicate reduced redness and itching associated with keloids when this ointment is off-label. This encourages research into its ability to promote healing.

C. Considerations for Use in Alopecia Areata

Finally, Tacroz Ointment can also treat alopecia areata, where nonscarring hair loss occurs due to a response. The immunosuppressive properties of Tacrolimus have the potential to disrupt the immune system activity associated with this disorder. While it's not a cure-all, Tacroz offers hope for those looking for aggressive systemic treatments. However, it's essential to consult with a professional before using the Tacroz Ointment label for alopecia areata and make informed decisions.


V. Mechanism of Action: How Tacroz Ointment Works

A. Inhibition of Calcineurin Enzyme

The effectiveness of Tacroz Ointment in therapy is based on its ability to block calcineurin, an enzyme involved in activating T cells. This blocking process is essential for how the Ointment works. Includes the following actions:

  • Reducing the production of pro-inflammatory cytokines.
  • Suppressing the growth of T cells usually leads to heightened immune responses.
  • They are slowing down the immune system's attack on skin cells, which is particularly important for treating autoimmune skin conditions.

The specific targeting of this enzyme is what makes Tacroz Ointment a leading option among immunomodulators.

B. Reduction of Inflammatory Cytokines

Tacroz Ointment works by inhibiting the action of calcineurin, which helps to decrease the production of cytokines. These cytokines are usually crucial for the body's defense mechanism. It can lead to chronic inflammation when too many are produced. Tacroz effectively reduces the release of these proteins, thereby reducing inflammation in the skin layers known as dermis and epidermis.

C. Immunosuppressive Effects on Skin

Moreover, the ointment has an effect on the skin, where it helps suppress the immune response. This, in turn, helps minimize the chances of worsening any existing skin conditions, promotes a state for the immune system in the skin, and aids in restoring both the structure and function of the skin. One advantage is that these immunosuppressive effects primarily occur at the site where the ointment is applied, reducing systemic exposure and associated side effects.


VI. Dosage and Administration of Tacroz Ointment

A. Standard Dosage Recommendations

The recommended way to use Tacroz Ointment3 depends on how severe the affected skin is and how much area it covers. Usually, it's suggested to apply a layer of the ointment to the affected area twice a day. However, the dosage frequency or amount may be adjusted depending on how your skin responds and tolerates it. It's essential to assess the dosage to make sure you're using the smallest adequate amount.

B. Methods of Application

Applying Tacroz Ointment requires attention. Here are some guidelines for patients:

  • Apply the ointment on dry skin gently without any harsh scrubbing.
  • Do not use dressings unless specifically instructed by a healthcare professional.
  • Avoid using topical treatments on the same area simultaneously to prevent any potential interactions.

C. Duration of Treatment Protocols

The length of treatment with Tacroz Ointment can vary greatly depending on the skin condition being treated. Patients need to follow the treatment plan their dermatologist recommends, even if their symptoms improve before completion. Caution should be exercised when considering long-term use, and regular evaluations should be conducted to determine if continued therapy is necessary. The duration of treatment can range from weeks to several months based on how the patient responds and any potential side effects.


VII. Side Effects and Adverse Reactions of Tacroz Ointment

A. Common Side Effects Encountered

Like any medication, using Tacroz Ointment can lead to some side effects. You may experience irritation at the application site, which could cause a burning or itching sensation soon after applying the ointment. Sometimes, you might notice some redness on the skin. It's usually temporary and goes away on its own. You might also feel a warmth or stinging sensation initially, but it tends to lessen with regular use. These side effects are typically harmless. Usually, they go away without needing any specific treatment.

B. Serious Adverse Effects and Allergic Reactions

Although rare, there can be side effects and allergic reactions linked to Tacroz Ointment. These may include itching, redness, or swelling that continues or worsens, indicating a potential hypersensitivity. It is also possible for skin infections to arise, which might require antibacterial treatment. Additionally, if any symptoms, like lymphadenopathy, occur, it is essential to stop using the ointment immediately and seek medical evaluation.

C. Managing Side Effects and When to Seek Medical Attention

It is crucial to manage any side effects that may arise to ensure that patients continue their treatment as prescribed. Here are some recommendations for addressing these side effects:

  • If you experience irritation, consider using a smaller amount of ointment or applying it less frequently.
  • To combat dryness or peeling, try using emollients.
  • If you notice any reactions or signs of systemic involvement, it is essential to consult with a healthcare professional immediately.

Patients should be informed about the difference between severe reactions so they can seek appropriate medical attention promptly.


VIII. Drug Interactions and Contraindications

A. Known Interactions with Other Medications

Tacroz Ointment might interact with medications. Some known interactions include:

  • When used with drugs that affect the skin barrier or cytochrome P450 enzymes, it may increase absorption into the body.
  • If combined with calcineurin inhibitors or potent immunosuppressive agents, it could lead to levels of tacrolimus in the bloodstream.
  • Additionally, using Tacroz Ointment alongside alcohol may cause blood vessels in the skin and heightened irritation.

B. Conditions Contradicting the Use of Tacroz

There are reasons why Tacroz Ointment might not be suitable for use, including:

  • If you have a known allergy or sensitivity to tacrolimus or any other ingredient in the ointment.
  • If you have existing conditions, like Netherton syndrome or other genetic issues that affect your skin's protective barrier.
  • If your immune system is compromised, it is essential to be extra cautious when using Tacroz because it may increase the risk of infections.

Please note that these are some factors to consider before using Tacroz Ointment.

C. Necessary Precautions with Other Topical Treatments

When incorporating Tacroz Ointment into a treatment plan, it is essential to take certain precautions:

  • Patients should avoid applying Tacroz at the same time as other topical products to prevent any interactions or blockage.
  • It is recommended to consider the time interval between applying Tacroz and other skincare products to ensure effectiveness and minimize the possibility of irritation.
  • Before starting any topical treatments, it is advisable to consult with a healthcare professional to confirm compatibility.


IX. Warnings and Important Precautions

A. Before You Use Tacroz: What to Tell Your Doctor

Before starting treatment with Tacroz Ointment, it's essential to discuss with your healthcare provider about critical things:

  • Any allergies you may have if they are related to the macrolide lactone compound called tacrolimus.
  • A detailed list of all the medications you are currently taking includes over-the-counter drugs and herbal supplements. This is important to prevent any drug interactions.
  • Your complete medical history, particularly if you have had viral infections or skin malignancies.

Having this conversation will help customize a treatment plan that minimizes risks and maximizes the effectiveness of the therapy.

B. Alcohol and Lifestyle Interaction

Drinking alcohol can potentially affect the effectiveness of Tacroz Ointment. It's advisable to refrain from consuming beverages as they could worsen the side effects of the ointment, like flushing or skin irritation. Additionally, it's essential to be aware of lifestyle factors that might interact with Tacroz, such as exposure to irritants.

C. Sun Exposure and Phototherapy Considerations

Patients using Tacroz Ointment should be careful when it comes to sun exposure. The ointment's effectiveness can be. The skin condition could potentially worsen due to ultraviolet light, whether from the sun or through phototherapy. Patients should take measures such as using broad-spectrum sunscreen and wearing protective clothing. Clinicians may also suggest adjusting phototherapy treatments while using Tacroz Ointment to ensure the safety and effectiveness of the treatment.

X. Special Considerations for Tacroz Ointment Administration

A. Administration to Elderly Patients

When using Tacroz Ointment on individuals, it is crucial to exercise caution. Closely observe for signs of the ointment being absorbed into the body or heightened sensitivity. Adapt the dosage or frequency of application depending on the patient's skin condition and kidney function, which can be affected as they age.

B. Usage During Pregnancy and Lactation

The use of Tacroz Ointment during pregnancy and breastfeeding requires an evaluation of its benefits and risks. Pregnant women should only use Tacroz if the potential benefits outweigh the risks to the baby under close medical supervision. Breastfeeding mothers should exercise caution since it is unclear whether tacrolimus is passed through breast milk and what impact it may have on the newborn.

C. Pediatric Use and Dose Adjustments

When using Tacroz Ointment in children, it is essential to be cautious about long-term usage because it may be absorbed into the body and affect their growth and development. Dosage adjustments may be required depending on the size of their body surface area and the severity of their condition. Regular monitoring of patients who are using Tacroz is essential to quickly address any adverse reactions or concerns related to their growth.


XI. Overdosage and Emergency Procedures

A. Identifying Symptoms of Overdosage

In cases where there is a use of Tacroz Ointment, it can be challenging to identify symptoms due to its topical application. However, it is essential to stay alert and watch out for signs such as more substantial adverse effects, mainly where the ointment was applied. Additionally, systemic manifestations like headaches, nausea, or dizziness may indicate that there has been much absorption. Recognizing these symptoms promptly is crucial for taking action promptly.

B. First Aid and Immediate Actions

If you suspect an overdose of Tacroz, it is essential to take action. Start by washing the affected skin using mild soap and water to remove any excess ointment. It's also important to avoid using dressings or applying heat to the affected area, as this can increase absorption. While these initial steps are not a replacement for medical advice, they can help minimize potential adverse effects while you wait for further medical assistance.

C. Contacting Poison Control and Seeking Medical Help

After giving medical assistance, it is essential to take the following steps:

  • Get in touch with Poison Control to get instructions for the current situation.
  • Seek medical attention and provide healthcare professionals with all relevant information, such as the quantity of ointment applied, exposure time, and any symptoms experienced.

XII. Storage Guidelines and Handling Precautions

To maintain the effectiveness of Tacroz Ointment and prevent it from deteriorating, it is essential to store it. It is advised to keep the ointment at room temperature, between 15°C to 30°C (59°F to 86°F). Additionally, make sure to store it from direct sunlight and any sources of heat that could potentially cause a breakdown of its active ingredients.

B. Disposal of Expired or Unused Ointment

It is essential to consider factors and safety protocols when disposing of Tacroz Ointment. Any ointment that has expired or is unused should be disposed of following regulations for medication disposal. One recommended method for eco-friendly removal of medications is through pharmaceutical take-back programs.

C. Safe Handling Practices to Prevent Contamination

To maintain the quality and safety of Tacroz Ointment, it is essential to follow handling procedures. Before and after applying the ointment, make sure to cleanse your hands to prevent any contamination. Additionally, it is crucial to avoid touching the tube's opening to keep it sterile and minimize the risk of contaminating the product.

XIII. Practical Tips for Careful Administration of Tacroz Ointment

A. Steps for Safe and Effective Application

To make sure you get the most out of Tacroz Ointment, it's essential to apply it. Here are the steps you should follow for effectiveness:

  • Start by cleaning the area where you'll be applying the ointment. Make sure your skin is dry and clean before you begin.
  • Use a tool or your clean fingertip to apply a thin layer of ointment to the affected area. Avoid rubbing vigorously, as this could make your condition worse.
  • After applying the ointment, give your skin some time to breathe. Let the medication absorb naturally. There's no need to cover up the area away.

By following these steps, you can ensure that Tacroz Ointment works effectively for you.

B. Avoidance of Contamination and Infection

Reducing the chances of contamination and infection is extremely important. Make sure to close the cap of the ointment tube after applying it to prevent bacteria from entering. Also, avoid using the ointment past its expiration date since its chemical stability cannot be guaranteed, which increases the risk of contamination.

C. Monitoring and Recording Treatment Progress

It is crucial to monitor the progress of the treatment. Please track how you apply it and any side effects or improvements you observe. This information will be beneficial during follow-up appointments. Additionally, regularly check the treatment area for signs of infection or adverse reactions. If you notice anything concerning, seek medical advice.

XIV. Conclusion: The Role of Tacroz Ointment in Dermatology

A. Summarizing the Benefits and Precautions

Tacroz Ointment has become a treatment option in the field of dermatology, providing relief to patients dealing with different skin conditions. However, it is crucial to follow precautions to avoid any potential side effects arising from its use.

B. Future Outlook on Tacroz Usage and Research Directions

The field of dermatology treatments is constantly changing. Tacroz Ointment is at the forefront of these new therapies. Ongoing research focuses on discovering uses for this ointment and improving its effectiveness, which expands the possibilities for dermatological care.

C. Final Thoughts on Patient Adherence and Care Coordination

In summary, the effectiveness of Tacroz Ointment depends greatly on patients sticking to their treatment plan and healthcare providers working together closely. Patients must have an understanding of how to use the ointment correctly and the significance of regular follow-ups so that they can get the best possible therapeutic results.

Rated: 5.0 / 5 based on 5.0 customer reviews.

Posted by palmer on Jan 10, 2019 Verified Purchase


well packaged fast delivery

Note: buy-pharma.md does not imply any medical claims from this review.
Posted by Ojeda on Jul 22, 2018 Verified Purchase

Tacroz forte

Nice presentation, good quality and convenient price, so just waiting to order again

Note: buy-pharma.md does not imply any medical claims from this review.
Posted by From Los Angeles California on Dec 24, 2017 Verified Purchase

Tacroz (Tacrolimus) Ointment works great

I do rely on this to keep my atopic dermatitis under control if I get a flare up - and this calms it right down - even making the 'itchy / raised / red' spot disappear within 24 hours of continuous application (meaning I apply it to the spot and leave it occluded with Scotch tape) for 24 hours and by that time, the 'flare up' is all gone. NO other medication will do this other than Tacrolimus - which I've used for years. So I know that what Buy Pharma is shipping is the real stuff - since it actually is quite effective in controlling a 'red-itchy-spot' flare-up. Highly recommend - great stuff - I apply with a toothpick so that I don't waste it - expensive stuff! I can usually get 1 tube to last me for years actually...

Note: buy-pharma.md does not imply any medical claims from this review.

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