Generic Diamox, Acetazolamide

Acetazolamide acts to restrain the action of carbonic anhydrase thus diminishing the production of bicarbonate. It is used for the medical treatment of glaucoma amongst others. Acetazolamide is also a weak diuretic.

Generic Diamox


Iopar-SR, AVVA


Wyeth Lederle, FDC, Intas Pharm

Capsule, tablet

250 mg



Acetazolamide is used in the treatment of glaucoma.
How it Works
Acetazolamide works to reduce the amount of fluid in the eye, which decreases pressure inside the eye. Acetazolamide reduces the activity of a protein in the body known as carbonic anhydrase. Blocking this protein can help reduce the build-up of certain fluids in the body such as the amount of fluid in the eye.
Common Side effects
Some of the potential side effects of Acetazolamide can include the symptoms below; Decreased potassium level in blood, Hearing dysfunction or tinnitus, Anorexia, Altered taste, Nausea, Vomiting, Diarrhea, Paresthesia, Drowsiness, Kidney stone Polyuria, confusion.
Expert advice
Before using Acetazolamide, inform your doctor about your current list of medications that you are taking, any allergies you may have, pre-existing diseases, and current health conditions such as if you are pregnant or if you have an upcoming surgery.Take this product as directed by your doctor, which will be adviced based on evaluation on your current health conditions. Some health conditions may make you more susceptible to the side-effects of Acetazolamide. Acetazolamide can cause Pulmonary obstruction and also Emphysema, therefore extra caution has to be taken while consuming this medication.
Should I consume Acetazolamide on an empty stomach, before food or after food? -Acetazolamide is normally consumed after food. However, we would advice you to follow your doctor's advice on how you should use this medicine. Is Acetazolamide safe to consume or apply when pregnant or breastfeeding? -Please consult with your doctor first. Can Acetazolamide cause kidney stones? -Yes, Acetazolamide can cause kidney stones
Acetazolamide is a carbonic anhydrase inhibitor. It increases the removal of water from the body by the kidneys and helps to relieve the pressure built up due to fluid accumulation. It also blocks certain nervous mediator releases that may lead to seizures.
Acetazolamide is used to prevent and reduce the symptoms of altitude sickness. This medication can decrease vomiting, tiredness, nausea, dizziness, and shortness of breath, which occurs when you climb to high altitudes, usually above 10,000 feet. This drug is also used in conjunction with other medications to treat glaucoma, caused by fluid build up in the eye. It is also used to decrease the amount of body fluids (edema) caused by congestive cardiac failure. It has also been used with other drugs to treat certain types of seizures (petit mal and other seizures).
Dosage and administration
It is available as tablets or capsules in the strength of 250 mg. It may be taken with or without food. The dosage is based on the patient’s medical condition and response to the therapy. The usual recommended dose is 250 mg to 1 gm daily, to be given in 1-4 divided doses. The tablet or capsule is to be taken orally with a glass of water. Long acting capsules need to be only taken 1 or 2 times in a day. The patient is advised to start taking the medicine 1 or 2 days before starting to climb high altitudes. Continue taking the medicine while climbing and for at least 2 days after reaching the final altitude. Take this medication regularly to get the maximum benefits from it. Do not stop using this medication without consulting the doctor. Some conditions may become worse when this drug is suddenly stopped. While withdrawing the drug, the dose needs to be gradually reduced.
The patient is advised to consult with the doctor about any allergies to the drug and about his or her medical history like liver disease, kidney disease, low levels of sodium or potassium in the blood, etc.This drug cannot cure the symptoms completely. In case of breathing problems and mood changes, it is advised that the patient descend to a lower altitude soon.This drug is known to affect the potassium levels of the blood hence it is advised to take potassium supplements while taking this drug with the consult of a doctor.The drug is known to make the patient dizzy. It is advised not to drive or get engaged in any of the activities which requires mental alertness.
Side effects
Some reported side effects when taking this medication include,NauseaVomitingDry mouthBlurred visionLightheadednessDizzinessDrowsinessLoss of appetiteStomach painHeadachesTiredness

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