Carprofen is a nonsteroidal anti-inflammatory drug for dogs that helps alleviate pain and inflammation due to osteoarthritis or surgery.

Generic Rimadyl



6, 30, 60

Veritas Pharma

Chewable Tablet

25 mg, 75 mg, 100 mg



I. Introduction

Brief Overview of Carprofen

Carprofen is a type of medication known as a steroidal anti-inflammatory drug (NSAID). It falls under the propionic acid class. It has gained significant recognition for its effectiveness in relieving inflammation, pain, and fever.

Importance in Medical Treatments

This medicine is particularly important in the field commonly used to relieve pain after surgery in animals. Additionally, its importance is highlighted by how it helps manage osteoarthritis in dogs.

Scope of the Article

In the sections, we will explore the chemical characteristics, applications, recommended doses, and safety precautions related to Carprofen.

II. Composition of Carprofen

Chemical Structure

Carprofen is a molecule with a shape represented by the chemical formula C15H12ClNO2. It consists of a part called acid and another part called phenyl ring, which allows it to reduce inflammation in the body.

Active and Inactive Ingredients

The main component of this medication is Carprofen. It also contains additional ingredients such as microcrystalline cellulose and sodium lauryl sulfate.

Available Forms (Tablets, Capsules, and Injections)

There are ways to access carprofen, such as through oral tablets, capsules, or injectable solutions. This flexibility allows for its use in a range of medical situations.

III. How Carprofen Works

Mechanism of Action

Carprofen acts as an inhibitor of cyclooxygenase, which hinders the production of prostaglandins. These prostaglandins are regulators in the process of inflammation.


Its strong preference for targeting COX 2 over COX 1 leads to effectively reducing inflammation while minimizing the usual stomach-related issues associated with NSAIDs.


Typically, the medication has a duration of around 8 hours in dogs. It goes through liver processing. It is mainly eliminated through the kidneys.

IV. Approved Uses of Carprofen

Treatment of Osteoarthritis

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation in dogs with osteoarthritis. It works by inhibiting an enzyme called COX2, which is responsible for producing inflammatory substances in the body. Carprofen can improve the quality of life of dogs with osteoarthritis by reducing their discomfort and enhancing their mobility12. However, carprofen is not a cure for osteoarthritis and it may have some side effects, such as liver damage, gastrointestinal ulcers, or bleeding disorders. Therefore, it is important to follow the veterinarian’s instructions and monitor the dog’s health while using carprofen3 .


1: Carprofen for Dogs: Osteoarthritis and Pain Management. 

2: Carprofen for Dogs - Understanding Your Dog’s Medication. 

3: Carprofen for Dogs: Uses, Dosage, Side Effects - 

: Carprofen for dogs: Dosage, uses and side effects | PetsRadar. 

Post-operative Pain Management

Carprofen, when given before or after surgery has shown to be effective, in reducing pain especially in spaying and neutering operations12Carprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation by inhibiting COX-1 and COX-2 enzymes3It is often used in combination with other analgesics for better pain relief4.

4: Rimadyl (Carprofen) for Dogs - American Kennel Club 3: Carprofen - Wikipedia 1: Carprofen for Dogs: Uses, Dosage, Side Effects - 2: Carprofen for Dogs - Understanding Your Dog’s Medication

Canine Medicine Applications

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation in animals, especially dogs. It can be used to treat osteoarthritis, as well as injuries in soft tissues or problems in the musculoskeletal system. Some of the references for this information are:

Carprofen - Wikipedia Carprofen for Dogs: Uses, Dosage, Side Effects - Carprofen | VCA Animal Hospitals

Other Veterinary Uses

  • Equine Medicine: Treatment of lameness
  • Feline Medicine: Limited use due to risk of toxicity

IVa. Off-label Uses

Inflammatory Conditions

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation in dogs and other animals. It can also reduce fever. Carprofen can be used for acute and chronic pain, such as arthritis, surgery, or injury. Carprofen was previously used in human medicine, but it is only FDA-approved to treat dogs in the United States.1 2 While it may not have received approval, Carprofen is occasionally used to relieve other types of inflammatory conditions, like dermatitis.3 However, this use is not recommended without consulting a veterinarian, as Carprofen can have serious side effects such as gastrointestinal bleeding, kidney damage, or liver failure.4 [5] References: 1 Carprofen: Uses, Interactions, Mechanism of Action - DrugBank 2 Carprofen - Wikipedia 3 Carprofen for Dogs: Uses, Dosage, Side Effects - 4 Carprofen for Dogs: Uses, Dosage, and Side Effects - The Spruce Pets [5] Carprofen for Dogs: Uses, Effectiveness & Side Effects - Policy Advisor

Chronic Pain Management

In some situations it is given to treat long term pain conditions even though there is not research available, on this specific topic.

Rheumatoid Arthritis

Carprofen is a non-steroidal anti-inflammatory drug (NSAID) that can help reduce pain and inflammation in dogs with osteoarthritis or other joint diseases12However, it can also cause gastrointestinal discomfort in some dogs, especially if given at high doses or for long periods of time34. Therefore, it is important to follow the veterinarian’s instructions and monitor your dog’s health when using carprofen.

1Carprofen for Dogs - Understanding Your Dog’s Medication 3Carprofen For Dogs: Uses, Dosage, Side Effects | Petco 2Carprofen for Dogs: Uses, Side Effects, Dosage, and Precautions 4Carprofen - Wikipedia

V. Dosage and Administration

Standard Dosage Recommendations

Typically, the amount of medicine given is based on a dog's weight and medical condition. When it comes to treating canine osteoarthritis, the usual dosage ranges from 2 to 4 mg, per kilogram of body weight taken by mouth.

Modes of Administration (Oral, Injectable)

The medication can be given either by mouth or through an IV injection, depending on the needs, at hand.

Va. Special Populations

Administration to Elderly

In adults, changes in drug metabolism often require modifications to the dosage.

Administration to Pregnant Women and Nursing Mothers

Because there haven't been studies, Carprofen is usually avoided in pregnant and breastfeeding females.

Administration to Children

Since Carprofen is mainly used in medicine, its relevance to pediatric populations is not relevant.

VI. Careful Administration

Pre-dose Evaluations

Before starting, it is advisable to conduct an evaluation that includes analyzing blood components and serum biochemistry.

Monitoring During Treatment

It is crucial to monitor the functioning of the liver and kidneys, especially during long-term treatments.

VII. Important Precautions

Renal Function

Carprofen should be used carefully in patients with kidney problems.

Liver Function

It is necessary to assess the liver's health to prevent potential damage.

Gastrointestinal Issues

You might want to consider giving gastroprotective agents like omeprazole at the time to prevent potential gastrointestinal problems.

VIIa. Warnings

Allergic Reactions

Although they are uncommon, anaphylactic reactions require discontinuation of Carprofen and prompt emergency intervention.

Drug Interactions

Using NSAIDs or corticosteroids at the same time can lead to negative interactions.

VIIb. Contraindications

Severe Renal Impairment

Carprofen should not be used in cases where there is renal insufficiency.

Known Allergies

Individuals with a documented sensitivity or allergic reaction to Carprofen or its components should refrain from using it. It is essential to consult with healthcare professionals to validate and supplement the information provided in this article.

VIII. Common Side Effects

Gastrointestinal Issues (Nausea, Vomiting)

Gastrointestinal issues that are frequently experienced include feeling nauseous and vomiting. These symptoms can occur after taking medication and may require medical attention. To help reduce nausea, doctors may prescribe drugs. Additionally, they might suggest fasting and staying hydrated as part of the treatment plan.

Elevated Liver Enzymes

An increase in liver enzymes is a side effect of using Carprofen. This abnormality, in biochemistry, could indicate liver problems. It is recommended to monitor liver function through tests. Adjusting the dosage or discontinuing the use of Carprofen may be necessary.


It is not uncommon, for patients or animals undergoing Carprofen treatment to experience fatigue. This drowsiness is usually temporary. It should not be ignored.

VIIIa. Rare Side Effects

Allergic Reactions

Allergies can sometimes show up in ways and can be pretty risky. Symptoms can vary from hives to severe anaphylactic reactions.

Hemorrhagic Diarrhea

An urgent side effect known as hemorrhagic diarrhea may occur in rare instances. If this happens, it is crucial to seek medical attention and consider stopping the medication.

IX. Overdosage

Symptoms of Overdose

Taking too much of a substance can lead to many issues, including acute kidney failure and bleeding in the digestive system.

Emergency Procedures

It is often advised to perform gastric lavage followed by giving activated charcoal to prevent the drug from being absorbed further.

Antidotes if Available

There is currently no known antidote for an overdose of Carprofen. Therefore the primary approach to managing cases involves providing symptomatic treatment.

X. Drug Interactions

With Anticoagulants

Taking anticoagulants, like warfarin with this medication may increase the chances of bleeding so it's essential to closely monitor and be cautious.

With Other NSAIDs

Taking NSAIDs simultaneously can lead to combined toxicity, which increases the chances of experiencing adverse effects.

With Corticosteroids

Using corticosteroids like prednisone in conjunction with each other can increase the risk of issues, including ulcers.

XI. Storage Requirements

Optimal Temperature

To ensure the effectiveness of the drug, it is essential to store it within a temperature range of 15 30°C.

Safety Measures

Please ensure that you store the item in a location that's cool and dry. It's essential to keep it out of reach of both children and pets.

Shelf Life

XII. Handling Precautions

Protective Gear

It is essential to wear protective gear like gloves, when administering Carprofen, especially if it is, in the injectable form.

Safe Disposal Methods

According to the guidelines, you should dispose of any medication that you don't use or that has expired, for handling waste in your community.

XIII. Summary and Conclusion

Recap of Key Points

This comprehensive guide provides in-depth information about Carprofen, including its ingredients, approved uses, off-label applications, and possible interactions, among essential aspects.

Expert Opinions

Veterinary experts and practitioners highly recommend Carprofen for treating certain conditions, such as canine osteoarthritis. However, they advise caution when administering it.

Further Reading Resources

  • Peer-reviewed journal articles focusing on the drug's pharmacokinetics and pharmacodynamics.
  • Veterinary Medicine Guidelines for NSAID administration.


Rated: 4.7 / 5 based on 4.7 customer reviews.

Posted by durden on Apr 14, 2020 Verified Purchase

Just as expected

This product is used for an elderly dog. It keeps her pain free with just one dose in the evening. I have noticed no difference in this and the product I get from her Vet. Very pleased. 

Note: does not imply any medical claims from this review.
Posted by Morehead on Mar 23, 2020 Verified Purchase

My dog feels better

I have to split the pills for my sized dog.  They are chewable but not according to my 17 year old mutt.  I tuck them inside a snack he likes or pile his favorite treat on top of the medicine.  It is meant to help pain and it has.  It may not be true but my old, nearly blind dog seems to be able to see a little bit better too.  I am so glad I found these.  No RX and great product.

Note: does not imply any medical claims from this review.
Posted by Baird on Feb 17, 2019 Verified Purchase

Thank you!

This medication helps my boxer with arthritis pain. It is affordable with buypharma.

Note: does not imply any medical claims from this review.
Posted by Brandt on Dec 29, 2018 Verified Purchase


Product was delivered timely and as ordered. Product is effective. Good company to deal with.

Note: does not imply any medical claims from this review.
Posted by Baird on Nov 3, 2018 Verified Purchase

Thank you!

Thanks to this product, my boxer is no longer lame and he feels so good. These pills are very expensive in the U.S. but thanks to BuyParma, we can afford to provide him with a better quality of life.

Note: does not imply any medical claims from this review.
Posted by Edwards on Sep 1, 2018 Verified Purchase

carporfen expriation date

great product, but short expiration date. Recommend buying what you need for no more than 6 months

Note: does not imply any medical claims from this review.
Posted by Kinzer on Apr 6, 2018 Verified Purchase

Good quality. Affordable.

This product was shipped in a timely manner. It is very affordable in contrast to other sites. It helps my dog get around easier because she is 15 years old and has severe arthritis.

Note: does not imply any medical claims from this review.

Customers also bought

Popular Products

Similar Product