Credelio Plus

Credelio Plus

Lotilaner/ Milbemycin oxime

Credelio Plus


Elanco Australia Pty Ltd, Elanco GmbH

Chewable tablet

56.25mg/2.11mg, 112.5 mg/4.22 mg, 225 mg / 8.44 mg


Credelio Plus

I. Introduction

Credelio Plus represents a breakthrough in veterinary medicine, providing a strong defense against various parasitic infections that affect our cherished pets. This piece seeks to highlight the ranging advantages, the detailed makeup, and the crucial role of Credelio Plus in safeguarding the health and happiness of animals.

II. Composition

Credelio Plus stands out due to its combination of key ingredients known for effectively fighting parasites. The formula is also enriched by incorporating additives that help improve the release and absorption of the active elements ensuring maximum efficiency against a broad range of parasites.

Key ingredients; A examination of the medicinal agents responsible for providing the therapeutic benefits of Credelio Plus.

  • Lotilaner: This medication kills fleas and ticks by interfering with their nervous system. It is effective against fleas within 4 hours of administration and ticks within 48 hours.

  • Milbemycin oxime: This medication works by paralyzing and killing intestinal worms and heartworm larvae. It is also effective against Demodex mites.

Additives and their roles; A closer look at the supplementary substances that are vital, for maintaining the medications stability and effectiveness. 

  • Cellulose
  • Silicon dioxide
  • Lactose
  • Povidone
  • Croscarmellose sodium
  • Beef flavoring
  • Magnesium stearate
  • Titanium dioxide
  • Ferric oxide

III. Uses

Credelio Plus is an innovative oral endectocide designed for dogs. It combines the safety and efficacy of milbemycin oxime with the novel administration of lotilaner. Milbemycin oxime has been used commercially for over 20 years, and lotilaner is an ectoparasiticidal isoxazoline present in a recently marketed monodrug product formulation (Credelio™). Credelio Plus effectively targets larval and adult stages of various canine nematodes, as well as major tick and flea species. It provides a reliable strategy to protect pets from parasites1.

IV. Off-Label Use

Credelio is commonly used for its main purposes, but veterinarians have also looked into using it for other purposes based on personal stories and case studies. However, they approach these uses with a consideration of the laws and ethics that regulate veterinary care.

V. How It Works

Credelio Plus works in an exciting way by interrupting the life cycles of fleas, ticks, and worms to protect against the diseases they can spread. Its effectiveness compared to parasite treatments shows the advanced research behind its development.

VI. Dosage and Administration

Credelio Plus administration is customized to meet the varying requirements of pets, taking into consideration their type, size, and individual health issues. The dosage instructions are carefully designed to achieve the results, emphasizing the timing and frequency of administrations for consistent protection levels.

VII. Side Effects

Like, with any medicine, Credelio Plus can cause side effects although they are usually minor and temporary. It's important for pet owners and vets to be aware of these reactions to differentiate between common side effects and those that require immediate medical attention.

VIII. Important Precautions

The safety of Credelio Plus is strong. However, there are situations where its use should be avoided. Extra care is needed when giving this medication to vulnerable groups, such as older pets, pregnant or nursing mothers, and young animals, to ensure that the advantages outweigh any possible dangers.

IX. Interaction

To ensure the safety and effectiveness of Credelio Plus it is crucial to understand how it interacts with medications.

  • This involves an understanding of the pharmacokinetics to prevent any negative reactions. It is important to be cautious of medications that could lead to harmful interactions, with Credelio Plus.
  • Additionally, we need to consider how Credelio Plus might impact tests, treatments, and dietary choices to maintain its effectiveness without any compromises.

X. Storage

Ensuring that Credelio Plus remains effective by storing it is crucial. The guidelines below are designed to keep its strength intact, ultimately safeguarding the well-being of the pets it's meant to help.

  • Store Credelio Plus in its original packaging at room temperature (between 68°F to 86°F [20°C to 30°C]).
  • Do not expose Credelio Plus to extreme temperatures (either hot or cold).
  • Keep Credelio Plus out of the reach of children and pets.

XI. Warning and Contraindication

When considering prescribing Credelio Plus, it's important to understand its limitations and potential dangers. Being aware of these factors is crucial for reducing the risks linked to its usage.

  • Specific warnings for each species should be taken into account tailoring precautions and instructions based on the biological and physiological characteristics of different animals.
  • It's essential to recognize any contraindications and risk factors associated with Credelio Plus to determine when it should not be used due to safety concerns.
  • Additionally, being prepared for reactions or hypersensitivity is crucial in handling any immune responses that may occur after administering this medication.

XII. Careful Administration

Administering Credelio Plus to pets with existing health issues requires careful consideration.

  • Adapting the treatment to each pet's needs is crucial for ensuring safety and effectiveness.
  • When dealing with animals with conditions,, it is important to tailor treatment plans to address these illnesses' unique challenges.
  • Regular monitoring is essential for long-term use of the medication to detect any adverse effects early on.
  • Adjusting dosages based on patient demographics and physiological needs is also key in optimizing treatment outcomes.

XIII. Administration to Special Populations

Certain groups of pets, such as ones, pregnant or nursing animals, and young ones, need extra attention to make the most of Credelio Plus while keeping risks minimal.

  • Older Pets; Adjusting treatment plans to consider the changes, in how drugs work and move through the body in elderly animals.
  • Pregnant Women and Nursing Mothers: Handling the challenges of giving Credelio Plus to ensure both the safety of the mother and her babies.
  • Young Animals: Adjust doses based on the growth stage and physical abilities of young pets.

XIV. Overdosage

In case someone accidentally takes much Credelio Plus, it is important to quickly recognize the situation and take action to prevent harm. Recognizing the signs and symptoms and knowing what to do can save lives.

  • Symptoms of overdose: signs that require urgent medical attention.
  • Immediate Remedies: Initial steps to alleviate the effects of an overdose.
  • Managing long-term effects of an overdose; Continued care plans to address any lasting issues from an overdose.

XV. Handling Precautions

Ensuring the use of Credelio Plus goes beyond just looking out for pets well being. It also involves safeguarding those who are giving the medication. By implementing safety protocols the chances of any exposure risks are reduced, creating a safe and secure setting, for everyone involved.

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