• Leflunomide
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Leflunomide is a disease-modifying antirheumatic drug that is prescribed to help manage rheumatoid arthritis.
US Brand Name Arava
Generic Name Leflunomide
Other Brand Name Lefra, Lefumide
Packing 10
Manufacturer Torrent Pharma, Cipla
Form Tablet
Strength 20 mg, 10 mg
Country India

  • 50 tabs 10 mg $44.50
  • 50 tabs 20 mg $89.50
  • 20mg 30Tab $39.00
Available online
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  • Lefumide, Generic  Arava,  Leflunomide 10 Mg Tablet (Cipla)
  • Lefra-10, Generic Arava, Leflunomide, 10mg, Strip
  • Lefumide, Generic  Arava,  Leflunomide 10 Tablet Box

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Leflunomide is used in the treatment of rheumatoid arthritis, psoriatic arthritis, reduces swelling and inflammation in the body.

How it Works

Leflunomide is known as a disease-modifying antirheumatic drug (DMARD). Leflunomide eases pain and stiffness associated with both of the conditions rheumatoid arthritis and psoriatic arthritis, and Leflunomide also reduces the damaging effect of the disease on Joints. Leflunomide works by blocking the way inflammation develops in joints. Leflunomide suppresses the underlying disease process, rather than simply treating the disease.

Common Side effects

Some of the potential side effects of Leflunomide can include the symptoms below;

Increased liver enzymes,
Respiratory tract infection.


Arava is a drug that is used for the treatment of arthritis. It has been used for two decades now. It alleviates pain by decreasing the inflammation in the joints. The generic name for this drug is leflunomide. TORRENT and Cipla manufactures this medicine. Other popular trade names are LEFRA and Lefumide.


Leflunomide which is the major ingredient of Arava is a pyrimidine inhibitor. Lactose monohydrate, crospovidone, colloidal silicon dioxide, talc, magnesium stearate, titanium oxide, starch, and ferric oxide are the inactive ingredients of this drug. This drug is usually consumed orally.


This medication is primarily used to treat rheumatoid arthritis especially of those that involve the cartilage of the joint. As per the statistics, women are more prone to arthritis in comparison with men. Its effect is to primarily reduce the symptoms and side effects caused by the disease. Usage of this drug will improve the physical functionality overall of a person suffering from arthritis. Recently, Arava has also been used for treating liver and hematologic conditions.

Dosage and administration

The ideal dosage interval for arthritic patient is 24 hours. Arava treatment can start with a dosage of 100 mg daily for three days straight. For maintenance therapy, it can be given with a starting dose of 20 mg. A much higher dose is said to have more side effects to patients at times. However, the dosage will be adjusted gradually by the doctor depending on the patient's condition.

Side effects

Some of the side effects of Leflunomide are Bloody or cloudy urine, cough, difficult or painful breathing, difficult, burning, or painful urination, dizziness, fever, frequent urge to urinate, headache and also loss of appetite.


Leflunomide has to be stored at room temperature. Leflunomide has to be kept away from light, extreme heat, moisture and cold. Keep Leflunomide out of the reach of children and pets.