Celecoxib
Uses
Celecoxib is used in the treatment of painful rheumatic conditions such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
How it Works
Celecoxib is known as a painkiller with anti-inflammatory effects, Celecoxib is also called non-steroidal anti-inflammatory drug or also known as a NSAID. Celecoxib works to ease pain and reduce inflammation. Celecoxib does this by blocking an enzyme in the body called cyclo-oxygenase-2 (COX-2). COX-2 is involved in the production of irritant substances in the body in response to disease. By blocking the action of COX-2, celecoxib reduces the symptoms of pain and inflammation in arthritis and provides relieve.
Common Side effects
Patients who take Celecoxib may suffer from such side effects;
Abdominal pain,
Palpitations,
Nausea,
Vomiting,
Edema,
Dyspepsia,
Flatulence,
Increased blood pressure,
Dizziness,
Headache,
Gastritis,
Heartburn,
Constipation,
Diarrhoea
Abdominal pain,
Palpitations,
Nausea,
Vomiting,
Edema,
Dyspepsia,
Flatulence,
Increased blood pressure,
Dizziness,
Headache,
Gastritis,
Heartburn,
Constipation,
Diarrhoea
Warning
Consult with doctor before taking celecoxib if you are suffering with any kind of heart disease.High risk of heart attack, heart failure, or stroke is observed when celecoxib is taken in high doses. It is advisble to not take celecoxib if you have or have recently had a coronary artery bypass , heart surgery, experienced stomach bleeding or have a history of stomach ulcers .
Overdosage
Overdose of Celecoxib can cause tiredness, weakness, nausea, vomiting, GI bleeding, and abdominal pain.
A large overdose can cause kidney failure, high blood pressure, difficulty breathing, and even cause patients to end up in a coma.
A large overdose can cause kidney failure, high blood pressure, difficulty breathing, and even cause patients to end up in a coma.
Storage
Storage is advisable at room temperature and keep celecoxib away from light. Do not store this medication in moist or damp areas, such as bathrooms.
Introduction
Celecoxib is used in the treatment of arthritis, ankylosing spondylitis, and menstrual pain. Celecoxib is a nonsteroidal anti-inflammatory drug or known as NSAID. Celecoxib US Brand Name is Celebrex. Celecoxib generic is also known as cobix Celecoxib is manufactured by SUN PHARMA and Cipla and it is approved by the drug research foundation FDA. It comes in capsule form. The strength of the pill varies from 100 mg to 200 mg.
Composition
The active ingredient of this drug is CELECOXIB. It has a molecular weight of 381.38.This drug contains the inactive components such as sodium sulfate, lactose monohydrate, gelatine, and povidone.
Use
Celecoxib is a nonsteroidal anti-inflammatory drug, specifically known as a COX-2 inhibitor. Celecoxib relieves pain and swelling or inflammation by by reducing hormones that cause inflammation and pain in the body. It is used to avoid the effect of the chemical called the Prostaglandins. Prostaglandins are responsible for pain.
Dosage and administration
Dosage should be taken as per advice by the doctor. For pain usually 200mg orally twice a day is needed. However, more accurate dosage is determined by your doctor upon checkup
Contraindication
It is necessary that you should inform your doctor on any medical conditions or allergies you have prior to consumption of celecoxib. You should avoid smoking and drinking when on celecoxib. You should not take celecoxib if pregnant.
Important Precautions
Before using celecoxib you should inform your doctor regarding your family history including if you have asthma, liver disease, stomach or intestine problems or heart disease.
Side effects
The side effects that are usually caused by celecoxib are cough, fever, skin rash, sneezing, sore throat, diarrhea, abdominal pains, indigestion or shortness of breath.
Storage
Celecoxib has to be stored at stoom temperature 25-30 degrees, It has to be kept away from extreme heat or moisture. Keep celecoxib away from children and pets.