Simvastatin
Uses
Simvastatin is used for the treatment of increased cholesterol levels in blood, triglycerides levels in blood and increased LDL levels in blood.
How it Works
Simvastatin is known as HMG-CoA reductase inhibitor. Simvastatin works by reducing the amount of cholesterol made by the liver. In most patients, simvastatin reduces the bad cholesterol and can actually raise the good cholesterol. Simvastatin regulates the amount of cholesterol and other lipids made by the body. Simvastatin does this by blocking the action of a certain enzyme called HMG-CoA reductase which your body needs to make the fats. This then lowers the risk of heart and blood vessel disease.
Common Side effects
Patients who take Simvastatin may suffer from such side effects;
Constipation,
Diarrhoea,
Stomach upset,
Nausea,
Headache,
Dizziness,
Musculoskeletal pain,
Allergic reaction,
Dyspepsia,
Nasopharyngitis,
Increased liver enzymes,
Joint swelling,
Increased glucose level in blood
Introduction
Simvastatin works to lower the cholesterol in our body. Simvastatin is produced by Cipla, Stancare Pharmaceuticals Div. of Ranbaxy Labs, IPCA and MHRA UK. Simvastatin has the US brand name Zocor. Simvastatin is also known as Simcard, Simlup, Simcard and Simlo. Simvastatin is manufactured in the form of tablets. Each tablet varies in strength. Usually, Simvastatin comes in various strength such as 5 mg to 80 mg. Simvastatin works to reduce fat or cholesterol production in our body.
Composition
The active component of this drug is SIMVASTATIN. The molecular weight of this substance is 418.57. It is a crystalline powder that is off-white in colour. Simvastatin contains ethanol, chloroform, and methanol soluble substance. Inactive components of the drug are starch, magnesium stearate, titanium dioxide, iron oxides, and talc.
Use
Simvastatin plays an important role in controlling your liver function. It helps to reduce bad cholesterol and improve the production of good cholesterol, So the fat production can be controlled. These actions are used to prevent the numerous diseases like heart attack and kidney failures. It also encourages weight loss by controlling actions of the liver.
Dosage and administration
It is advisable to seek medical advice before taking Simvastatin. It is necessary to inform your doctor regarding any medical conditions that you have prior to taking Simvastatin.Simvastatin should be consumed after food in the evening. You should take the medicines after three hours of your other normal medications.
Contraindication
You should also follow the diet and the exercises routine that is advised by your doctors. It should be necessary that you avoid alcohol while you're taking the medicines. It is also essential to avoid smoking.
Important Precautions
If you have liver and kidney problems, do not use this drug since it may cause failure of your kidneys. Pregnant women are also advised not to use the medications up to the end of breastfeeding period since it may affect the new-born babies. It is advised that if you are having any side-effects when taking medications immediately stop taking medicines and consult with your doctor.
Side effects
The drug may cause dangerous side effects if the treatment is not taken properly. It may cause a fever that can cause reduction in body weight . You may have stomach pain or heart burn from taking the medicines. In case of this situation, you should consult with your doctor. Some people may get pain in their muscles.
Storage
The medicines should be kept away from children and pets, and it is best when you keep the medicines at the temperature of 25 degrees. Keep Simvastatin away from extreme heat and moisture.