Tianeptine
Uses
Stablon Tianeptine is used in the treatment of depression
How it Works
Stablon Tianeptine increases the amount of circulating serotonin available in your brain, Serotonin works to stimulate other neurons in the brain that stimulates mood and physical symptoms in depression. Stablon Tianeptine works by increasing the activity of serotonin in the brain which it achieves by inhibiting the reuptake of serotonin. Altering the balance of the chemicals in the brain can help with the symptoms of depression.
Common Side effects
Patients who take Stablon Tianeptine may suffer from such side effects;
Abdominal pain,
Dry mouth,
Loss of appetite,
Premature ventricular complex,
Precordial pain,
Dizziness,
Headaches,
Trembling,
Breathing difficulties,
Throat tightness,
Muscle aches,
Lower back pain,
Vomiting,
Flatulence,
Insomnia,
Change in heartbeat,
Drowsiness,
Nightmares,
Weakness
Introduction
Stablon, Tianeptine 12.5 mg is prescribed as an atypical antidepressant and is being marketed in many countries. Unlike other drugs used for depression, this drug is reported to increase the rate of Serotonin uptake. Structurally, this novel molecule is thought to reduce stress induced damage to the brain. It is also assumed to play a role in influencing other excitatory neurotransmitter pathways, such as glutamate transmission. The efficacy of this drug in major depressive states and anxio-depressive episodes is significant.
Use
Stablon, Tianeptine 12.5 mg is primarily being used to treat major depression. It is also used in managing severe depressive episodes and anxio-depressive states. It significantly improves the psychosomatic symptoms and helps in treating depression associated with Parkinson's disease and post-traumatic stress disorder. Patients who experience lack of interest in daily events, certain abnormalities, loss of appetite, fatigue, attention deficit, or suicidal tendencies can use this drug too when advised by a doctor. Unlike other drugs of this group, this drug does not possess anti-cholinergic, sedative, and cardiovascular side effects. It has become a drug of choice for elderly patients and individuals with alcohol withdrawal symptoms. This drug is reported to have positive effects on the brain thus it is also currently being prescribed to enhance memory in cases of early dementia.
Dosage and administration
This drug is available in 12.5 mg tablets and is generally prescribed as a twice or thrice daily regimen. Recently, sulfate salt combined with this drug in 12.5 mg dose is being developed, which causes it to be less readily absorbed, hence making it a once daily dosing. The drug should be withdrawn gradually by decreasing the dosage over 7-14 days.
Warning
Detailed history of drugs taken and previous hypersensitive reactions should be noted before being prescribed this drug.
It is not to be given along with monoamine oxidase inhibitors.
Alcohol consumption is discouraged as it decreases the absorption of this drug.
This drug is contraindicated for pregnant ladies, lactating mothers, and children below 15 years old.
It is not to be given along with monoamine oxidase inhibitors.
Alcohol consumption is discouraged as it decreases the absorption of this drug.
This drug is contraindicated for pregnant ladies, lactating mothers, and children below 15 years old.
Side effects
Side effects are most common in patients on prolonged therapy.
Reduced sleep or insomnia
Tremors
Body aches
Weight gain
Nausea
Diarrhea
Episodes of constipation
Other minor side effects are,
Dry mouth
Flatulence
Epigastric pain
Dizziness
Drowsiness
Headaches
Physicians must consider to withdraw the drug from the regimen if patients develop rare symptoms like palpitation and hepatitis. Chronic treatment with this drug has abusive and addiction potential thus it must be cautiously used.
Reduced sleep or insomnia
Tremors
Body aches
Weight gain
Nausea
Diarrhea
Episodes of constipation
Other minor side effects are,
Dry mouth
Flatulence
Epigastric pain
Dizziness
Drowsiness
Headaches
Physicians must consider to withdraw the drug from the regimen if patients develop rare symptoms like palpitation and hepatitis. Chronic treatment with this drug has abusive and addiction potential thus it must be cautiously used.