Tretinoin Gel Microsphere

Tretinoin Gel Microsphere is used for the treatment of acne. Tretinoin Gel Microsphere is a retinoid which works to decrease the formation of pimples and promote quick healing. Tretinoin Gel Microsphere works by effecting the growth of skin cells.

Generic Retin A Micro

Tretinoin Gel Microsphere

Supatret, Retino A Micro, MyTret and other generic brands

15g, 20g

Sun Pharma, Janssen, HAB Pharmaceuticals and others


0.04%, 0.1%


Out of Stock.

Tretinoin Gel Microsphere


Introduction to Tretinoin Gel Microsphere

The introduction of the Tretinoin Gel Microsphere represents an advancement in the field of dermatology. This specific formulation, derived from vitamin A, is widely recognized for its effectiveness in addressing a variety of skin issues. Its primary mechanism involves accelerating cell turnover and regulating the process of keratinization, resulting in a skin appearance. The importance of this product in treatments cannot be emphasized enough.

Tretinoin has played a role in enhancing therapy for different skin conditions, supported by thorough scientific research and endorsements from clinical professionals. Its proven efficacy in treating acne vulgaris signs of aging caused by sun exposure and other dermatological concerns has solidified its position as a component in skincare practices.


Composition of Tretinoin Gel Microsphere

  • Ingredients and their functions: The main active ingredient found in Tretinoin Gel Microsphere is tretinoin, which plays a key role in speeding up cell turnover. This process is crucial for removing the layers of skin and rejuvenating the cells underneath.
  • Understanding technology: This innovative technology involves enclosing tretinoin within tiny spherical formulations. This design aims to release the medication, reduce skin irritation, and improve the stability of the active ingredient. This, in turn, enhances its absorption and effectiveness.


Uses of Tretinoin Gel Microsphere

Acne treatment: How Tretinoin Gel Microsphere works and its effectiveness

  • Tretinoin Gel Microsphere tackles acne by clearing out pores by adjusting the differentiation of skin cells. This process helps prevent the formation of comedones, a major contributor to acne. The success of tretinoin in managing acne is supported by clinical trials that have demonstrated significant enhancements in both acne severity and skin quality.


Photoaging: Advantages and supporting evidence

  • Addressing photoaging concerns, Tretinoin Gel Microsphere helps reduce signs of aging, such as fine lines, wrinkles, and uneven skin tone. Applying this formulation topically has been proven to stimulate collagen production, an element in maintaining skin flexibility and tightness. Scientific research confirms that regular usage leads to improvements in overall skin condition.


Keratosis Pilaris: Usage and outcomes

  • While not intended for this purpose, Tretinoin Gel Microsphere has displayed effectiveness in treating Keratosis Pilaris. This condition is characterized by rough bumps on the skin, which benefit from tretinoin's exfoliating properties. Studies suggest that individuals experience smoother skin texture and reduced bumpiness after treatment.


Other uses in dermatology

  • Apart from its uses, Tretinoin Gel Microsphere is employed for treating various other dermatological conditions, such as pigmentary disorders and precancerous skin lesions. Its wide range of uses and flexibility make it a valuable tool in the field of dermatology.


Off-Label Uses of Tretinoin Gel Microsphere

Tretinoin for hair growth; Discoveries and research

  • While Tretinoin Gel Microsphere has long been known for its benefits in dermatology, it also shows promise in promoting hair growth. Early studies indicate that tretinoin could help other topical treatments penetrate the skin better and encourage hair follicles to enter the growth phase, offering an additional option for managing alopecia. Insights from studies underscore its potential when used alongside other treatments.


Treating hyperpigmentation: How well does it work?

  • Tretinoin Gel Microsphere can also effectively address symptoms like melasma and post-inflammatory hyperpigmentation conditions. Tretinoin helps fade discoloration and improve skin texture by speeding up cell turnover. While results may vary there is evidence supporting its use especially when combined with other depigmenting agents.


Reducing stretch marks; Research findings.

  • The use of Tretinoin Gel Microsphere to reduce stretch marks has shown results. Clinical trials have shown that tretinoin can improve the appearance of red stretch marks more effectively than older silver ones. It works by boosting collagen production and repairing the skin structure, resulting in a smoother and more even skin surface.


How Tretinoin Gel Microsphere Works

  • The science behind Tretinoin and cell turnover: Tretinoin works by speeding up the renewal process of skin cells, helping improve skin health and clearing skin issues.
  • The impact of Tretinoin on collagen production: Tretinoin Gel Microsphere can also boost collagen synthesis in the layers of the skin, strengthening its structure and reducing the visibility of wrinkles.
  • Addressing inflammation and pore blockage: Tretinoin has inflammatory properties and can help unclog pores, making it an effective solution for treating acne and similar skin conditions.


Dosage and Administration

Different conditions require different dosages of Tretinoin Gel Microsphere; for treating acne, it's usually recommended to apply a pea-sized amount once daily in the evening. However, for conditions like photoaging or keratosis pilaris, applying it frequently may be better to avoid irritation.

To achieve the best results when using Tretinoin Gel Microsphere:

  • Make sure to apply it to clean, dry skin.
  • Gently dabbing can help with absorption.
  • Reduce the chances of skin irritation.
  • Remember not to apply the gel near your eyes or mouth unless a healthcare professional advises.

The frequency and duration of treatment with Tretinoin Gel Microsphere depend on factors like skin type and the severity of the condition being treated. Improvement may become visible after weeks or months, and continuous use is often needed to maintain the positive effects.


Common Side Effects of Tretinoin Gel Microsphere

Peeling and dryness are concerns when using Tretinoin Gel Microsphere as it speeds up the shedding of skin cells. To address this issue, it is recommended to;

  • Keep moisturized with a non-comedogenic hydrating cream to combat dryness without blocking pores.
  • Ease into incorporating Tretinoin Gel Microsphere into your skincare routine by starting with applications every night.


When it comes to sun sensitivity caused by Tretinoin, which can make your skin more prone to sunburn, it's crucial to;

  • Apply a spectrum sunscreen daily with an SPF of 30 or higher.
  • Wear protective clothing and wide-brimmed hats to defend against direct UV exposure.


If you're experiencing redness and irritation in the initial stages of treatment, consider these tips for relief;

  • Ensure your skin is dehydrated before applying the gel to reduce irritation.
  • A soothing product, like aloe vera or a light hypoallergenic lotion, can help ease discomfort.


Important Precautions and Warnings

When using Tretinoin Gel Microsphere, it's essential to be aware of the increased sensitivity to UV radiation. To protect your skin, apply a SPF sunscreen and limit your exposure to the sun to prevent sunburn and premature aging.

It's essential to be cautious of interactions between Tretinoin and other skincare products or medications. Some products containing benzoyl peroxide, sulfur, or salicylic acid may cause increased skin irritation when used with Tretinoin. Additionally, certain medications that make the skin more sensitive to light can amplify the effects of Tretinoin on sun sensitivity.

There are situations where it's best to avoid using Tretinoin Gel Microsphere;

  • If you have eczema or sunburn, Tretinoin can worsen these conditions.
  • Right after waxing or any hair removal, it can increase skin sensitivity.


Contraindications of Tretinoin Gel Microsphere

There are situations and conditions in which Tretinoin Gel Microsphere should not be used;

  • Individuals with a known sensitivity to Tretinoin or its components should refrain from using it.
  • Additionally, severe skin conditions like eczema or rosacea could worsen with the use of Tretinoin.

When it comes to pregnancy and nursing, Tretinoin falls under FDA pregnancy category D, indicating a risk to the fetus if used by pregnant women. Due to the risk of absorption and harm to the fetus or nursing infant, it is advised not to use Tretinoin Gel Microsphere during pregnancy and nursing.

Administration to Special Populations

Special care and adjustments are necessary when administering Tretinoin Gel Microsphere to individuals due to their skin's increased sensitivity and thinning with age.

  • These adjustments may involve using concentrations and applying them less frequently to reduce the chances of irritation.
  • It's essential to monitor their skin condition and hydration levels as aging skin tends to be more prone to dryness.


Regarding the use of Tretinoin in children under 12, it is generally not recommended except for older children with severe acne, where it can be cautiously prescribed.

  • The safety and effectiveness of using this gel in patients must be carefully evaluated against the risks of systemic absorption and potential long-term effects on a developing child.
  • Children should only use Tretinoin under medical supervision with dosages tailored to minimize exposure while ensuring therapeutic benefits.


For women and nursing mothers, using Tretinoin Gel Microsphere is typically discouraged due to its potentially harmful effects on fetuses or infants through breast milk.

  • Pregnant women should avoid this treatment altogether to prevent any harm to the baby.
  • Nursing mothers are advised to either refrain from using the product or seek advice from healthcare professionals for alternatives.


Interaction with Other Drugs

Interactions with prescription and over-the-counter medications should be carefully considered when using Tretinoin Gel Microsphere, as they can affect its effectiveness and the health of the patient's skin. This medication is known to interact with topical acne treatments, leading to possible skin irritation or dryness. Additionally, it can react with photosensitizing agents, increasing the risk of sunburn.

Furthermore, herbal supplements and vitamins may also impact how Tretinoin Gel Microsphere works. For example, supplements like St. John's Wort could make the skin more sensitive to sunlight, while high doses of Vitamin A might worsen any effects associated with tretinoin. To ensure safety and effectiveness, patients should inform their healthcare provider about their medications to prevent any interactions.


Handling and Storage of Tretinoin Gel Microsphere

To keep the Tretinoin Gel Microsphere, it's important to store it correctly.

  • Store it at room temperature away, from sunlight and moisture.
  • Always close the cap tightly when not using it to prevent drying out.

When handling Tretinoin Gel Microsphere, wash your hands before and after applying the gel to prevent bacteria from spreading. Only use the amount your healthcare provider prescribes to avoid overuse and potential side effects.

Overdosage and Its Management

Symptoms of taking too much Tretinoin Gel Microsphere may include worsened side effects like intense skin irritation, peeling, and redness. You might also experience systemic issues such as headaches, dizziness, and digestive discomfort.

If you suspect an overdose, here's what you should do;

  • Stop using Tretinoin Gel Microsphere away to prevent further absorption.
  • Clean the area with gentle soap and water to get rid of any leftover medication.
  • Consult healthcare to determine if you need treatment for your symptoms.
  • This could involve using moisturizers for skin irritation or other supportive measures for problems.


Careful Administration and Monitoring

To ensure Tretinoin therapy is effective, monitoring how the skin responds and making any necessary treatment adjustments is essential. These adjustments may be needed based on factors such as."

  • The severity of skin irritation
  • Changes in skin condition due to the therapy.

Modifying the dosage or frequency of application can help reduce effects while achieving therapeutic benefits.

For optimal treatment outcomes with Tretinoin Gel Microsphere, structured follow-up care is crucial. This includes:

  • Dermatological assessments to track treatment effectiveness and make any needed changes.
  • Patients should also receive guidance on managing any side effects that may arise during treatment.


Concluding Remarks

Tretinoin Gel Microsphere shows promise in dermatology, especially for treating acne photoaging and various skin conditions. Its effectiveness is boosted by its microsphere formulation, which allows for controlled release and minimizes skin irritation, making it a valuable asset in dermatological treatments.

Looking ahead, the future of Tretinoin in dermatology appears bright. Research is exploring its potential for a wider range of skin issues and seeking ways to improve its formulation to enhance patient compliance and treatment outcomes.

Continued advancements and clinical studies will likely clarify Tretinoin's role in dermatology further. While Tretinoin Gel Microsphere is a dermatological treatment option, it is crucial to handle its administration with care to prevent potential overdosing and ensure that its usage is closely monitored for optimal therapeutic results.

Rated: 4.9 / 5 based on 4.9 customer reviews.

Posted by R on Nov 28, 2021 Verified Purchase

Effective Gel

This microphere gel feels a bit grainy, but it gets the job done! I like that it's time released and seems to be a bit more gentle even at the higher strengths and I like how lightweight it feels on my skin. I has helped my acne and overall skin tone and made me feel more confident in my appearance.

Note: does not imply any medical claims from this review.
Posted by Jo on Oct 8, 2018 Verified Purchase


Great service from Buy pharma, and great product. Will continue to use.

Note: does not imply any medical claims from this review.
Posted by COTE on Jul 21, 2018 Verified Purchase

Great product

Packaging is in another language, but works great and a fraction of the cost!

Note: does not imply any medical claims from this review.
Posted by Arnold on Jul 12, 2018 Verified Purchase

Tretinoin gel microsphere 1 %

Fast delivery, great product, thank you

Note: does not imply any medical claims from this review.
Posted by Arnold on Jun 12, 2018 Verified Purchase

Tretinoin microsphere 0.1%

Thank you very much, very fast delivery amazing work product, Hi recommending

Note: does not imply any medical claims from this review.
Posted by Facial Product Maven on Jun 6, 2018 Verified Purchase

Better than a lactic acid peel

Fine gel with a slightly greasy feel and granular texture when released from the tube, yet spreads easily and is surprisingly light and non-greasy when worn. It gradually sloughs away the skin's tired surface layer without the overdrying and wrinkling effect of a glycolic or lactic acid peel.

Note: does not imply any medical claims from this review.
Posted by Weber on May 14, 2018 Verified Purchase

Excellent --Just as expected

This is exactly as described. Was shipped quickly and I received in less than 2 weeks.

Note: does not imply any medical claims from this review.
Posted by Keown on Jan 11, 2018 Verified Purchase

Retin A - Wonderful!!

I have been using this site for several years - Robert is wonderful! This product is perfect. Great price and great product. Highly recommend!!

Note: does not imply any medical claims from this review.
Posted by Marian on Aug 31, 2017 Verified Purchase

Great Customer Service

Product as described, speedy delivery, great customer service. Over and above service.

Note: does not imply any medical claims from this review.
Posted by Jessie on Aug 6, 2017 Verified Purchase

Retin-A Micro Gel

Great product. Supratret (generic) works as well as the Valeant prescription product. I have both and use both concurrently. Both are effective for acne and keeping the skin smooth. The Supatret consistency is smoother, so easier for application.

Note: does not imply any medical claims from this review.
Posted by Lorrie on Feb 18, 2017 Verified Purchase


It was exactly as expected.

Note: does not imply any medical claims from this review.
Posted by Lorrie on Jan 1, 2015 Verified Purchase

Amazing results!

I have been using this for about 3 weeks and I'm shocked my the level of improvement in my skin. I would highly recommend this!

Note: does not imply any medical claims from this review.

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