Cyclophosphamide
  • Cyclophosphamide
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Cyclophosphamide

1 customer reviews.
Cyclophosphamide is an alkylating agent prescribed to treat various types of cancer. It is also prescribed to treat nephrotic syndrome in children after other treatments have proved inadequate.
US Brand Name Cytoxan; Neosar
Generic Name Cyclophosphamide
Other Brand Name Ledoxan, uniphos
Packing 50
Manufacturer Dabur, United Biotec, Cadila
Form Tablet
Strength 50 mg
Country India

  • 50 tabs 50 mg $24.50
Available online

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  • Cyclophosphamide

    Cyclophosphamide

    Generic Name:Cyclophosphamide
    Form:Tablet, Injection
    Strength:50 mg, 100 mg, 200 mg, 500 mg
    $3.90-$9.90
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1

Details

Cyclophosphamide

Uses

Cyclophosphamide is used in the treatment of several types of cancer such as, blood cancer, breast cancer, non-small cell lung cancer and ovarian cancer.

How it Works

Cyclophosphamide is known as an anti-cancer medication. Cyclophosphamide works by damaging the genetic material or the DNA of the cancer cells and stops their growth and multiplication thus stopping the spreading of the cancer cells in the body.

Common Side effects

Some of the potential side effects of Cyclophosphamide can include the symptoms below

Mucosal inflammation,
Decreased white blood cell count,
Infection,
Fever,
Blood in urine,
Hair loss,
Urinary tract infection,
Bone-marrow suppression

Introduction

Cyclophosphamide is an antineoplastic drug that is used for the treatment of various types of cancer. It is usually used in combination with other drugs. It is also an immunosuppressive and thereby is used in nephrotic syndrome treatment in children, when other treatments have proved ineffective.

Use

Due to its antineoplastic properties, it is used in the treatment of various types of cancer like leukemia, lymphoma, Hodgkinโ€™s disease, mycosis fungoides, neuroblastoma, retinoblastoma, ovarian cancer, breast cancer as well as others. Its mechanism of action is by cross-linking the two strands of DNA of the tumor cells, which are then not capable of dividing. It is also used in the treatment of nephrotic syndrome or other kidney problems in children.

Dosage and administration

For cancer: -

Intravenous: - For both children and adults, it is administered intravenously in the dose of 40-50 mg/kg body weight in divided doses over a period of 2-5 days. The subsequent maintenance dose depends on the body's response to the drug.

Oral: - The usual oral dose is 1-5 mg/kg body weight that is to be taken daily.

For nephrotic syndrome: -

The normal dose is 2-3 mg/kg body weight that is to be given daily for a period of 8-12 weeks.

Warning

Inform your doctor if you are allergic to Cyclophosphamide or to any other substances. Also, conditions like decreased bone marrow activity (anemia, neutropenia, thrombocytopenia, etc.) or any history of liver disease or kidney disease must be informed.
Since it is an immunosuppressive, avoid engaging in any activities that may cause a cut or a bruise. Also, inform the doctor about the drug use before going for any surgery or dental treatment.
Do not go for vaccinations or immunizations without consulting your doctor when on this drug.
It is to be used with caution in children and elderly patients. Such patients must only use this medicine with a doctor's prescription.
Women kept on this drug regime are strictly advised not to become pregnant when using this drug and at least one year after the drug is discontinued since the drug is known to have teratogenic effects on the fetus. Women are advised not to breast feed while using this drug as well.
Patients with risks of pulmonary toxicity, cardiac toxicity, or urinary bladder toxicity must be closely monitored during the entire drug regime. This drug is also known to cause infertility by affecting spermatogenesis and oogenesis.
In case of any severe anaphylactic reactions like swelling of the lips or mouth, skin rash, itching, unusual weakness, bloody stools, dark urine, infertility, etc., discontinue the drug use and consult your doctor immediately.

Side effects

Vomiting
Nausea
Diarrhea
Stomatitis
Jaundice
Oral ulcers
Fever with chills
Darkening of the skin or nails
Hair loss
Irregular menstrual periods
Difficulty in or painful when urinating

Customer Reviews

Rated: 5.0 / 5 based on 1 customer reviews.

product review

Posted by Swentzel on Jun 18, 2018 Verified Purchase

excellent product, great service

Note: buy-pharma.md does not imply any medical claims from this review.