Duoflam Plus, Aceclofenac/ Paracetamol

Duoflam Plus (Ibuprofen/Paracetamol/Anhydrous Caffeine) is prescribed to alleviate the signs and symptoms of osteoarthritis or rheumatoid arthritis, as well as to manage pain associated with a variety of conditions. It may also be prescribed to reduce fever and to allay minor aches and pain caused by the common cold or flu.

Duoflam Plus

Aceclofenac/ Paracetamol

Duoflam Plus


Svizera, Maneesh Pharma


Aceclofenac100 mg / Paracetamol 325 mg




Aceclofenac is used in fever, headache, arthralgia, myalgia, dental pain, osteoarthritis, post operative pain, pain during menstruation, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and gout.

How it Works

Aceclofenac is known as a non-steroidal anti-inflammatory drug (NSAID). Aceclofenac works by blocking the release of certain chemical messengers that cause fever, pain, inflammation, redness and swelling.Aceclofenac works by blocking the effect of natural substances called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes using Aceclofenac, fewer prostaglandins are produced, which means pain and inflammation are eased.

Common Side effects

Patients who take Aceclofenac may suffer from such side effects;

Dyspepsia and flatulence,
Soreness affecting the abdomen,
An increase in the amount of liver enzymes in the blood

Expert advice

Before using Aceclofenac, inform your doctor about your current list of medications that you are taking, any allergies you may have, pre-existing diseases, and current health conditions such as if you are pregnant or if you have an upcoming surgery. Some health conditions may make you more susceptible to the side-effects of Aceclofenac. Take this product as directed by your doctor, which will be adviced based on evaluation on your current health conditions. Aceclofenac can increase the risk of blood clots, heart attack, or a stroke,therefore extra caution has to be taken with this medication. Aceclofenac can also cause serious complications like stomach bleeding and kidney problems if taken for a extended amount of time. It is advisable to take aceclofenac with food or milk to avoid experiencing an upset stomach.


Should I consume Aceclofenac on an empty stomach, before food or after food?
-Aceclofenac is normally consumed after food. However, we would advice you to follow your doctor's advice on how you should use this medicine.

Is Aceclofenac safe to consume or apply when pregnant or breastfeeding?

Can Aceclofenac be used for pain relieve?
-Yes, Aceclofenac is most commonly used for pain relieve as it is a pain reliever.



Paracetamol is used in the treatment of reducing fever, and relieving pain such as headache, pain during menstruation, arthralgia, myalgia, dental pain and post operative pain.

How it Works

Paracetamol inhibits and blocks the production of pain and inflammation-causing chemicals called prostaglandins. Prostaglandins are found throughout the body, but paracetamol mainly works on those in the brain that are responsible for pain and fever.

Common Side effects

Patients who take Paracetamol may suffer from such side effects;

Allergic reaction,
Liver damage,


Duoflam Plus is a well known drug that is famous for its antipyretic as well as analgesic effects. This is generally used to deal with pain and relief from fever. It can reduce the effect of arthritis by decreasing pain near the joints.


Duoflam Plus can reduce the effect of arthritis by decreasing pain near the joints. It works in a specific way to reduce the pain that is generated due to fever and other joints problem. It helps to stimulate the brain cells, muscles and heart.The effectiveness of the pain relievers is mainly affected by the presence of this drug, which is the combination of paracetamol, ibuprofen, and caffeine. The benefits of this drug make it perfect to be used to cure minor to major pain.

Dosage and administration

It contains caffeine at 25mg, paracetamol at 500mg, and ibuprofen at 400mg. This drug is available in the form of tablet and thus should be consumed orally. Do not chew the tablet. Administration advice should be followed according to what the doctor has given.


Pregnant ladies may experience medical complications after consumption of these tablets. It is best to seek medical advice before consumption of this medication. Mainly it is advised that pregnant women should avoid the intake of this medicine during pregnancy unless deemed safe by the doctor.

Important Precautions

Breastfeeding mothers should also avoid the intake of these tablets as there can be complications after intake of this tablet.

Side effects

Side effects are always associated with drugs and hence proper care must be taken while consuming this drug to get rid from pain. Few of the side effects are as follows, Use of overdose can lead to generation of anxiety related problem, nausea,The rate of heart beat increases, Insomnia, tremors and also headaches.


Duoflam Plus should be stored at room temperature away from children and pets. it should also be kept away from direct sunlight, heat and moisture.

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