Phenazopyridine Hydrochloride

Phenazopyridine HCl is prescribed to help alleviate pain, burning, as well as frequent and urgent urination due to infections or other conditions that irritate the urinary tract. When diagnosed with a urinary tract infection, Phenazopyridine HCl helps provide symptomatic relief, however, it does not treat the infection itself.

Generic Pyridium, Prodium, Pyridiate, Baridium, Uricalm, Urodine




Menarini India


200 mg


Phenazopyridine Hydrochloride


Phenazopyridine Hydrochloride, commonly known as a medication for tract pain, provides relief from the symptoms of pain, burning sensation, and discomfort associated with urinary tract infections and other related conditions. This medication mainly works as a pain reliever for the urinary system. It has been widely used since receiving FDA approval for its effectiveness in easing discomfort during instances of cystitis and other minor irritations in the system.

Definition and Overview of Phenazopyridine Hydrochloride

Phenazopyridine Hydrochloride is a man made azo dye substance used for its pain relieving effects in the system. It doesn't cure infections. Helps ease the symptoms related to urinary issues giving patients relief while they receive treatment, for the root cause of their symptoms.

Historical Development and FDA Approval Status

Phenazopyridine Hydrochloride, first introduced in the 1900s has been a go to treatment in urology for many years. This medication was approved by the FDA for its effectiveness and is commonly used as a complementary therapy, in urological treatments especially for handling symptoms linked to urinary tract infections.

Composition of Phenazopyridine Hydrochloride

The medicine contains phenazopyridine as its component, which is what gives it its healing properties. It is typically mixed with substances, in tablet form to improve how the drug is delivered.

Active Ingredients and Excipients

The main component that drives the drugs impact is phenazopyridine. Other substances found in the formula, such as magnesium povidone and corn starch play a role, in ensuring the tablets strength and absorption capabilities.

Variations in Formulations (tablets, capsules)

  • Tablets are often recommended because they are convenient to use and provide dosing.
  • Capsules offer an option, for those who prefer them over tablets.

Mechanism of Action: How Phenazopyridine Hydrochloride Works

Phenazopyridine Hydrochloride works by being eliminated through urine providing a soothing pain relief effect, on the lining of the tract. This helps ease the pain burning sensation and discomfort linked to irritation in the urinary tract just like Methenamine.

Pharmacodynamics: Pain Relief Processes in the Urinary Tract

The pain relief provided by the medication comes from its capacity to calm the lining of the tract, which helps alleviate discomfort without directly acting as an antiseptic, for the urinary system.

Absorption and Metabolic Pathways

Following ingestion Phenazopyridine is quickly taken up from the stomach and intestines where its effectiveness relies on being excreted through urine. Once in the urine it. Provides a direct calming impact, on the irritated mucous membranes.

Clinical Uses of Phenazopyridine Hydrochloride

Phenazopyridine hydrochloride is a medication used for the symptomatic relief of pain, burning, urgency, frequency, and general discomfort caused by lower urinary tract irritations. These irritations can result from infection, trauma, surgery, endoscopic procedures, or the passage of equipment or catheters12. It affects the lower part of the urinary tract, including the bladder and urethra. Common urinary symptoms it helps address include pain or burning during urination, increased urination, and an increased urge to urinate13.

Phenazopyridine hydrochloride side effects

Phenazopyridine Hydrochloride works well in easing discomfort. It can also cause different side effects that patients should know about.

Common Side Effects: List and Description

  • Patients frequently mention a change in urine color ranging from orange to red, which is considered harmless but noticeable.
  • Some individuals have experienced headaches typically of mild intensity and short duration.
  • There may be instances of stomach discomfort, like nausea or abdominal pain.

Severe Reactions and Management Strategies

In cases certain serious responses may require prompt medical intervention.

Hemolytic Anemia, indicated by symptoms like tiredness, paleness or yellowing of the skin calls for immediate attention.

  • Renal Toxicity should be considered if patients report side pain or changes in urination patterns to prevent harm to the kidneys.
  • Dermatologic Reactions such as skin conditions, like Stevens Johnson syndrome necessitate stopping the medication and seeking urgent medical help.

phenazopyridine warnings

It's important to be aware of the safety measures linked to Phenazopyridine Hydrochloride before administering it.

phenazopyridine warnings

Contraindications: Conditions and Drug Interactions

This medicine should not be used by individuals with health issues.

  • For example, if someone has kidney problems the drug may build up in their system cause harm.
  • Also those who have had reactions, to Azo dyes in the past should steer clear of this medication.

Warnings: Potential Risks and Adverse Reactions

There are risks to be aware of:

  • Avoid using it for a long time as it might hide any hidden health issues.
  • Also keep in mind that Phenazopyridine could affect the outcomes of urine tests and evaluations of kidney function.

Interactions with Other Medications

Phenazopyridine Hydrochloride interactions with medications changing how well they work or causing more side effects.

Pharmacological Interactions: Enhancements or Reductions in Efficacy

Some important things to consider are:

  • When taking antibiotics they might work better in treating tract infections when used together.
  • Using NSAIDs along, with medications could potentially raise the chances of experiencing side effects related to the kidneys.

Recommendations for Managing Interactions

To handle these interactions efficiently:

  • Patients need to make sure they tell their healthcare providers about all the medications they are currently taking.
  • It is recommended to keep an eye out for any reactions when beginning or discontinuing Phenazopyridine.

Overdose and Management

Taking much Phenazopyridine Hydrochloride can have serious consequences and needs prompt medical care.

phenazopyridine dosage

Symptoms of Overdose

Symptoms could involve Acute Kidney Failure, characterized by reduced urine production and swelling well as Intense Digestive Discomfort, like nausea or stomach ache.

Immediate Actions and Antidotal Therapies

  • When dealing with an overdose it's important to provide support by ensuring the person stays hydrated and maintaining their balance.
  • To reduce absorption activated charcoal can be given after ingestion as part of gastric decontamination.
  • Additionally specific symptoms such, as nausea or pain should be treated as they occur.

Handling and Storage Instructions

Ensuring that Phenazopyridine Hydrochloride is handled and stored correctly is crucial, for preserving its effectiveness and reducing safety hazards.

Optimal Storage Conditions to Maintain Efficacy

Please store Phenazopyridine Hydrochloride in a dry spot away, from direct sunlight. It's best to keep it at a temperature range of 15 to 30 degrees Celsius (59 to 86 degrees Fahrenheit) to maintain the potency of the components.

Handling Precautions for Healthcare Providers and Patients

Both healthcare providers and patients should be cautious when dealing with Phenazopyridine Hydrochloride.

  • It is important to avoid inhaling the powder from tablets as well as direct contact with broken tablets to prevent staining and potential irritation.
  • Proper disposal of expired medication is also crucial to prevent accidental ingestion or environmental contamination.

By following these guidelines the potential risks associated with Phenazopyridine Hydrochloride can be reduced, offering an option for patients in need of relief, from urinary tract discomfort.

Rated: 5.0 / 5 based on 5.0 customer reviews.

Posted by ch on Mar 28, 2020 Verified Purchase

definitely genuine

all properties match, behaves as expected

Note: does not imply any medical claims from this review.

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