Sildenafil works for the treatment of erectile dysfunction or impotence or inability to get or keep an erection during sexual activity. It is also used to improve exercise capacity in men and women with Pulmonary arterial hypertension (PAH) (high blood pressure in the arteries carrying blood to the lungs from the heart).
How it Works
Sildenafil for patients with erectile dysfunction, works by preventing the action of a chemical called, phosphodiesterase type-5. This works to widen and relax the muscles in blood vessels in the penis and increases blood flow. This helps to produce and maintain an erection .For Pulmonary arterial hypertension or PAH Sildenafil works by relaxing the muscles in the walls of the arteries, which then allows the blood vessels to become wider, This reduces the pressure in the arteries and allows blood to flow more easily through them. This then increases the supply of blood to the lungs and directly improves the ability to do exercise
Common Side effects
Patients who take Sildenafil may suffer from such side effects;
Insomnia (difficulty in sleeping),
Sildenafil is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.
Sildenafil should not be taken by :
-People who also take nitrates such as nitroglycerin (glycerin trinitrate),
as this may drop in blood pressure.
-Under 18 years
-Men hypertensive to Sildenafil
-Alpha -blockers (anti hypertensive drug)
-Men with end-stage illnesses like liver or kidney disorder , anemia or leukemia, prostate enlargement, serious heart complications, uncontrolled high blood pressure, longstanding nervous disorders
Sildenafil can produce mild dizziness as side effects; hence, it is advisable not to indulge in outdoor activities or operate heavy machinery. Patients should only take the dosage when needed.
Overdose symptoms may include chest pain, nausea, severe dizziness, fainting, irregular heartbeat.
If you experience any of the symptoms above, seek emergency medical attention.
Store Sildenafil at room temperature away from direct sunlight and moisture.
Keep the medicines out of the reach children.
Lidocaine is used for local anesthesia (numb tissues in a specific area)
How it Works
Lidocaine works by stopping sodium from entering the nerve endings at the site of pain, Pain is caused by the stimulation of pain receptors at the ends of nerves, this causes sodium to enter nerve endings which then causes an electrical signal to build up in the nerve. This electrical signal then passes along the nerve to the brain and interpreted as pain. When lignocaine stops sodium from entering the nerve endings it temporarily blocks the pathway of pain signals along nerves to the brain thus temporarily numbing the local tissue in that area.
Common Side effects
Patients who take Lidocaine may suffer from such side effects;
Feeling sick and vomiting,
Shaking, usually of the hands (tremor),
Pins and needles (paraesthesia),
Sensation of ringing, or other noise in the ears (tinnitus), or increased sensitivity to noise,
Low blood pressure (hypotension),
Slow heart rate (bradycardia),
Shortness of breath,
Slow, shallow breathing (respiratory depression),