Mesalazine is an anti-inflammatory agent that is prescribed to help treat mild to moderate ulcerative colitis as well as to prevent the symptoms of ulcerative colitis from recurring.

Asacol, Mezavant, Octasa, Pentasa

Mesalazine,Mesalamine (USAN) or 5-aminosalicylic acid

Walasa, Mesacol, Mesacol OD


Win-Medicare, Sun Pharma, Wallace Pharma

Tablet, Delayed Release Tablet

400 mg, 500 mg 800 mg, 1200 mg




Mesalazine is used for the treatment of ulcerative colitis and crohn’s disease.

How it Works

Mesalazine is known as a aminosalicylate. Mesalazine is used to threat ulcerative colitis which can cause Symptoms that include pain in the abdomen and severe diarrhoea that often contains blood and mucus. This is caused by swelling of the large intestine. Mesalazine relieve these symptoms by relieving inflammation of the intestine, thereby reversing the symptoms caused by ulcerative colitis.

Common Side effects

Patients who take Mesalazine may suffer from such side effects;

Loss of hair,
Pain affecting the ears,
Muscle stiffness or aches,
Abdominal pain


Ulcerative colitis, a condition of the large intestines or colon that is difficult to manage, is treated by the drug, Mesalazine. Due to its anti-inflammatory property, the drug is widely used as a mainstay therapy for colitis patients. Many patients across the world are put on this medication by doctors and gastroenterologists after being diagnosed with the disease. It is manufactured and marketed by various reputable companies. In concentrations of 400 mg, 500 mg, 800 mg, or 1200 mg, the tablet form of this drug is usually available in packs of thirty, since it is necessary to take the medication on a long term basis so as to keep the patient in a stable condition.


This drug has anti-inflammatory properties that help suppress the inflammation in the colonic wall and thereby protect the patient from related symptoms. Such patients experience diarrhoea and pain, along with blood mixed with the mucus. Once diagnosed with ulcerative colitis, treatment starts immediately with the required dose and it is continued on a long term basis to help manage the disease and keep the patients on remission.

Dosage and administration

Dosage of the drug is usually given twice a day or as prescribed by the doctor. For cases of mild and moderate ulcerative colitis, it is advised to take two tablets of 400 mg three times a day so that the condition improves. For maintenance dose, one tablet of 800 mg can be taken two times daily for a period of 6 weeks or as directed by the doctor. Sometimes, this medicine is to be continued for some months unless the patient is relieved of all the symptoms.


Patients having previous allergies to salicylate drugs should avoid taking this drug.
Difficulty in breathing, rashes, chest tightness or other negative symptoms on consumption of this medicine may suggest hypersensitivity. Stop taking the medicine and consult the doctor immediately.
Pregnant ladies and children are to avoid this drug.
All the necessary precautions advised by the pharmacist or doctor should be followed strictly to get full advantage out of this drug.

Side effects

Being an anti-inflammatory drug of the salicylate group, this drug has a number of side effects that should be immediately brought to the attention of the treating physician when experienced. Side effects like loss of hair, blood in the urine, gastritis, or haemorrhoids are to be reported to the doctor as soon as possible. The doctor will then decide whether the dosage should either be reduced or it is best to stop prescribing the drug completely thus immediate consultation with the doctor is necessary.

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