Rabipur Injection

Rabies antiserum vial is a passive immunization against rabies. This medicine is administered to a patient when they come in contact or have been in contact of animals which have or are presumed to be infected with rabies.

Rabipur Injection

Rabies antiserum

Rabipur Injection


Sanofi Aventis, GSK


2.5 IU


Out of Stock.

Rabipur Injection

Introduction to Rabipur Injection

Overview of Rabipur Injection

Rabipur Injection is mainly used as a vaccine to prevent rabies. It is given to people who may come into contact with the rabies virus typically spread through bites, from animals.

Importance in Preventing Rabies

Rabies is an illness with a mortality rate close to 100% in individuals who have not been vaccinated once symptoms appear. Rabipur is essential for protecting against this virus, offering immunity that can stop rabies symptoms from developing following exposure.

Rabies immune globulin

Rabies immune globulin is administered alongside the rabies vaccine to prevent infection from the rabies virus. It functions by providing your body with the antibodies to defend against the rabies virus, offering a form of passive protection. This temporary shield remains effective until your body can generate its antibodies to fight off the rabies virus. Rabies immune globulin is given to individuals who have encountered an animal suspected or confirmed to carry rabies, such as through a bite, scratch, or lick. This process is known as exposure prophylaxis and is reserved for those who have not previously received the rabies vaccine.

Composition of Rabipur Injection

Active Ingredients

The main ingredient in Rabipur is the deactivated rabies virus, which guarantees both safety and effectiveness.

Pharmaceutical Formulation Details

Rabipur is designed as a freeze-dried product that, when mixed with a liquid, provides the inactive substances required to stimulate an immune reaction without inducing illness.

Uses of Rabipur Injection

Primary Uses: Rabies Prophylaxis

Rabipur is mainly administered to protect individuals who have been bitten by an animal suspected of carrying rabies or for those at risk of coming into contact with the virus.

Situational Uses: Post-Exposure and Pre-Exposure Immunization

Off-Label Uses of Rabipur

Exploring Non-Standard Applications

Rabipur is made specifically for treating rabies. Scientists are exploring its possible uses in other preventive treatments for viruses.

Clinical Studies and Evidence Supporting Off-Label Use

Recent research indicates that there is potential for Rabipur to be beneficial, in situations but thorough testing is ongoing to confirm its effectiveness and safety.

How Rabipur Injection Works

Mechanism of Action Against Rabies Virus

Rabipur triggers the body's defense system to create antibodies that fight off the rabies virus, providing a shield of immunity that can effectively counteract the virus when encountered.

The Immune Response Initiation

The vaccine functions by introducing a deactivated virus, which triggers the immune system to respond and create memory cells without causing the illness.

Dosage and Administration of Rabipur

The amount of Rabipur you take remains the same for all ages, with a dose of one mL given through an intramuscular injection.

Step-by-Step Administration Guide

The shot should be administered in the shoulder area of the arm or for children on the front side of the thigh.

Timing and Frequency of Doses

In exposure prevention you will receive four doses on days 0 3 7 and 14. For exposure prevention it is advised to take three doses on days 0 7 and either 21 or 28.

Signs of rabies in dogs

  • Common indicators of rabies in dogs to be mindful of include fever, swallowing challenges, increased salivation, stumbling, seizures, and potential paralysis.
  • As the infection advances your dog might exhibit signs of being overly sensitive to stimuli, with lights, motion and noise seeming to bother them.

Symptoms of rabies in cats

  • Changes in behavior can manifest as a decrease, in appetite indications of anxiety or unease irritability and heightened excitability.
  • The animal might start to prefer solitude, or an unfriendly animal could display friendliness.
  • Unusual aggressiveness may arise; a calm and obedient animal could turn aggressive.

Side Effects of Rabipur Injection

Common Side Effects: Mild Reactions

Swelling, redness, and discomfort at the spot where the injection was given are typical. They are usually not severe and temporary.

Serious Side Effects: Rare Reactions

In some cases, people might have allergic reactions, like anaphylaxis, that need urgent medical care.

long-term side effects of rabies vaccine in humans

After receiving the rabies vaccine some individuals have experienced side effects such, as Guillain Barre syndrome, anaphylaxis, encephalitis (extremely rare) meningitis (very rare) and retrobulbar neuritis.

Detailed Analysis of Interactions

Drug Interactions: Pharmaceuticals and Rabipur

Rabipur, like any medication, could interact with other drugs, possibly changing how well they work or raising the chance of negative reactions. It's important to be cautious when giving it alongside medications as they might weaken the immune response triggered by the vaccine.

Interaction with Vaccines and Biologicals

The combined use of Rabipur with vaccines has been carefully examined. Specifically, live vaccines might affect the response triggered by Rabipur. It is commonly advised to give vaccines either two weeks before or two weeks after administering Rabipur to prevent any potential interactions.

why does rabies cause hydrophobia

Animals and humans infected with rabies could exhibit unpredictable or hostile actions, showing an increase in saliva production and foam at the mouth. Individuals showing signs of rabies may also suffer from painful muscle spasms, in the throat particularly when attempting to swallow water.

Storage and Handling of Rabipur

Optimal Storage Conditions

It's important to keep Rabipur in a fridge between 2 and 8 degrees Celsius. To ensure its strength and effectiveness, shield the vaccine from light and freezing.

Shelf Life and Expiry Information

The Rabipur usually lasts for 3 years from the manufacturing date if kept in the right conditions. Make sure to check the expiration date, on the packaging before using it to make sure it's still good.

Warnings and Contraindications

Specific Health Conditions and Risks

If someone is allergic to any part of the Rabipur vaccine, like neomycin, a leftover residue, from making it, they should steer clear of using it. Also those facing fevers or acute infections should hold off on getting vaccinated.

Who Should Not Receive Rabipur?

Expectant mothers should carefully weigh the advantages and drawbacks as the safety of Rabipur during pregnancy remains uncertain. Moreover, those with weakened systems might not develop optimal immunity through vaccination.

rabies shot for dogs

Puppies need to reach an age of about 12 to 16 weeks to get their initial rabies shot. This initial shot is known as the primary dose, and the follow-up vaccination is administered within a year of the one.

rabies vaccine for cats

Rabies poses a threat to cats as it is invariably lethal, and unfortunately, there is no cure once contracted. The best approach is prevention. A single dose should be administered one year after completing the series followed by subsequent doses every three years.

Special Considerations in Administration

Administering to Elderly Patients

Older individuals might show an immune reaction to vaccines. It's important to evaluate their health condition and any existing medical issues before giving them the Rabipur vaccine.

Guidelines for Pregnant Women and Nursing Mothers

During pregnancy, it is advisable to use Rabipur is essential, as there have been no direct associations with fetal harm. Additionally nursing mothers should exercise caution since it is uncertain whether the vaccine elements are passed into breast milk.

Safety and Efficacy in Children

Rabipur has been proven safe and effective for children with a dosage that remains consistent across all age groups. This makes it a reliable choice for treating individuals who are, at risk of rabies exposure.

Managing Overdosage of Rabipur

Signs and Symptoms of Overdose

In cases taking too much Rabipur could cause increased swelling or serious allergic reactions, around the injection area.

Immediate Actions and Treatment

In case of an overdose, it is advisable to provide treatment for the symptoms. Healthcare providers should focus on monitoring signs and checking for anaphylactic reactions, as top priorities.

Important Precautions with Rabipur

Before Receiving Rabipur: What to Know

Patients should share their background with their healthcare provider particularly mentioning any past negative reactions to vaccines. It's important to inform healthcare professionals about allergies or immune system issues, for a vaccination process.

Monitoring and Safety Measures Post-Administration

Patients who have taken Rabipur should be monitored for any side effects. It is important to inform a healthcare provider of any unusual symptoms to ensure timely intervention.

Handling Precautions for Healthcare Providers

Safe Handling Practices

Healthcare professionals are required to follow vaccination procedures, such as using clean equipment, wearing gloves, and correctly disposing of needles and syringes to avoid contamination between patients.

Disposal and Safety Protocols

Dispose of used vials, syringes and other disposable items following the guidelines for biomedical waste. This practice is essential, for reducing harm and preventing needle stick injuries among healthcare workers.

how much is a rabies shot US

The price of a rabies vaccine typically falls between $40 and $75 per dose. Some affordable vaccination clinics or animal shelters may provide it at a discounted rate, especially if it is bundled with necessary pet vaccinations. Remember, your dog will require rounds of shots along with boosters.

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