Zomelis, Vildagliptin

Zomelis, a form of vildagliptin, is used to help manage blood sugar in people with type 2 diabetes. It works by using the body's natural processes to steadily control blood sugar without causing significant weight changes or a high risk of low blood sugar episodes. This makes it a great option for long-term metabolic treatment, often used in combination with metformin for better results.

Vildagliptin works by temporarily blocking the enzyme DPP-4, which helps prolong the effects of the hormones GLP-1 and GIP in your body. This helps you control blood sugar.
Zomelis is one of the brand names for vildagliptin tablets. In other places, the original brand is sold as Galvus, while the combination with metformin is sold as Galvus Met.

The European Medicines Agency (EMA) approved vildagliptin (marketed as Galvus) in 2007 for adults with Type 2 diabetes. However, as of 2025, it has not yet been approved by the U.S. FDA.
In India, the Zomelis brand was initially launched under a licensing agreement but is now owned by Eris Lifesciences. You can easily find Zomelis Met, a combination of vildagliptin and metformin, in pharmacies across India. Following the loss of exclusivity rights, the Indian market now has increased competition among brands like Zomelis and Zomelis Met.

Vildagliptin (ATC code A10BH02) is a DPP-4 inhibitor that helps manage blood sugar by improving insulin function and regulating glucagon levels. It works based on your glucose levels, which means it lowers HbA1c without a high risk of low blood sugar. This makes it a great option for older people with irregular eating habits or those who are prone to hypoglycemia. However, it's important to have regular liver function tests, and the drug should be used with caution in patients with liver problems.

Each tablet of Zomelis includes vildagliptin, as the ingredient with the label indicating a 50 mg dosage, per tablet though certain markets may offer a 100 mg option well.

Vildagliptin is available in single-ingredient tablets, most commonly in a 50 mg strength, but 100 mg tablets are also available in some places.
For combination therapy, fixed-dose tablets containing vildagliptin and metformin are common. These come in specific strengths:

• 50 mg of vildagliptin combined with 500 mg, 850 mg, or 1000 mg of metformin.
• The tablets are typically taken once or twice a day, depending on the patient's kidney function and tolerance.
• Some versions also use slow-release (SR) metformin, and in some areas, slow-release vildagliptin is also available.

The standard ingredients found in cores usually consist of anhydrous and microcrystalline cellulose along, with sodium starch glycolate and magnesium stearate as common additives for the film coating that could include hypromellose alongside iron oxides and talcum powder with macrogols and titanium dioxide being additional components, in some variations depending on the manufacturer and regulations in place.

Combining vildagliptin and metformin is effective because they work in different ways to control blood sugar. Vildagliptin improves the body's natural hormone response, while metformin reduces the amount of glucose the liver produces and increases insulin sensitivity in the body's tissues.

Doctors usually aim for a daily dose of 100 mg of vildagliptin along with up to 2000 mg of metformin, adjusting the dose based on a patient's kidney function and how well they tolerate it. Research and real-world results show that using a fixed-dose combination of these two drugs can help patients reach their treatment goals more quickly.
It is also worth noting that metformin is particularly helpful for controlling blood sugar between meals, while vildagliptin is more effective at managing post-meal sugar spikes. Additionally, gastrointestinal issues with metformin often improve when a sustained-release version is used.

Both sitagliptin and vildagliptin are in the same class of drugs called DPP-4 inhibitors and are effective at controlling blood sugar. However, their dosing schedules are different: sitagliptin is usually taken once a day at 100 mg, while vildagliptin is typically taken twice a day at 50 mg.
Studies show both drugs are similarly effective at lowering HbA1c, although some data suggest that vildagliptin might have a slight edge at its standard dose. A key difference is that sitagliptin is approved by the U.S. FDA, but vildagliptin is not.
The choice between these two medications often depends on factors like availability, a patient's other health conditions, and local insurance or healthcare policies.

Compared to the sulfonylurea drug glimepiride, vildagliptin is much less likely to cause dangerously low blood sugar (hypoglycemia). This is because vildagliptin's action is dependent on glucose levels, meaning it only boosts insulin when your blood sugar is high.
Studies show that while both drugs effectively lower HbA1c levels, vildagliptin results in far fewer cases of confirmed hypoglycemia and doesn't cause weight gain, unlike glimepiride. Although glimepiride is a powerful and cost-effective option, vildagliptin is often preferred when a primary goal is to avoid low blood sugar. In some regions, a three-drug combination of glimepiride, vildagliptin, and metformin is also available.

Vildagliptin works by blocking an enzyme called DPP-4, which normally breaks down hormones known as incretins (GLP-1 and GIP). By inhibiting this enzyme, vildagliptin allows incretin levels to rise, leading to a more balanced insulin response that is based on your body's glucose levels. It also helps control glucagon, especially when blood sugar is high.

By increasing the levels of GLP-1 and GIP in the body, both when you're fasting and after you eat, vildagliptin improves how your body's beta-cells respond to blood sugar. This helps the body produce a more robust and rapid insulin response, which in turn leads to better control of blood sugar spikes after meals.

As blood sugar levels rise, the body releases more insulin to prevent them from getting too high. At the same time, the release of glucagon from alpha cells is reduced. This helps lower the liver's glucose production and keeps blood sugar levels stable throughout the day.

Clinical data shows that treatment with this medication improves certain markers of beta-cell function, such as HOMA-B and insulin secretion. While there isn't enough evidence to call the drug "disease-modifying," studies suggest it helps preserve beta-cell function, which aligns with its mechanism of action on incretin hormones. The medication also works well when combined with metformin treatment.

Zomelis, Vildagliptin is approved for adults with type 2 diabetes as a single-drug treatment when diet and exercise aren't enough. As a single therapy, it systematically lowers both fasting and post-meal blood sugar levels.
The extended-release formula improves tolerance and adherence for those who experience stomach issues with regular metformin. The medication works by decreasing the amount of glucose produced by the liver and increasing glucose absorption in the body's tissues, which leads to smoother blood sugar control throughout the day.

For patients whose blood sugar isn't well-controlled with metformin alone, adding Zomelis, Vildagliptin can be very helpful. This combination works by using two different but complementary methods:

• Metformin lowers the amount of glucose produced by the liver and increases the body's sensitivity to insulin.
• Gliclazide, a sulfonylurea, stimulates the pancreas to release more insulin.

Together, these two medications are more effective at lowering HbA1c levels than either drug on its own. This combination also allows doctors to use lower doses of each drug, which can reduce the risk of side effects while still being highly effective.

AlthoughZomelis, Vildagliptincontains a sulfonylurea, it can sometimes be combined with other medications to achieve better blood sugar control in specific, challenging cases. This isn't a common practice because of the increased risk of low blood sugar, but it can be an option when a patient needs specialized care. In some situations,Zomelis, Vildagliptin is used to replace other sulfonylurea medications because it offers more consistent blood sugar control and enhanced safety.

Zomelis, Vildagliptin can be used with insulin for people with advanced type 2 diabetes who aren't responding well to oral medications alone. This dual approach helps by:

• Lowering the amount of insulin needed which can reduce the risk of weight gain and low blood sugar.
• Improving blood sugar stability by addressing both insulin resistance and the pancreas inability to produce enough insulin.
• Making the treatment more balanced and tolerable which can improve patient satisfaction.

This combined treatment is especially helpful for patients who have had diabetes for a long time and need more intensive measures to control their blood sugar.

The main purpose of Zomelis, Vildagliptin is to help people achieve and maintain long-term blood sugar control. It works by addressing both a lack of insulin and insulin resistance at the same time, which helps lower both your fasting blood sugar and the spikes that happen after meals.
Over time, this consistent control helps reduce the risk of long-term diabetes complications. This includes small vessel diseases (microvascular complications) like kidney damage, nerve damage, and eye problems, as well as large vessel diseases (macrovascular complications) that affect the heart and blood vessels.

Zomelis, Vildagliptin have been studied in people with prediabetes because they can improve insulin sensitivity and reduce liver glucose production. This could help delay or even prevent the onset of type 2 diabetes.
Observations suggest that starting these medications early may help lower fasting blood sugar, stabilize post-meal spikes, and protect the pancreas's beta cells from burnout. Although this is considered an "off-label" use, it may be an option for individuals with a family history or other risk factors for diabetes to help protect their future blood sugar control.

Studies on Zomelis, Vildagliptin have found that it can help with weight loss. The medication works in several ways: it helps control appetite, changes gut bacteria, and reduces glucose production in the liver. This effect is especially noticeable in people with insulin resistance.
Recent research also shows that Zomelis, Vildagliptin can lower triglyceride levels, which improves fat metabolism. Patients often report feeling fuller and consuming fewer calories overall.
While not a dedicated weight-loss drug, Zomelis, Vildagliptin can be an effective tool for weight management when combined with a healthy diet and regular exercise.

Research shows that metformin-based treatments like Zomelis, Vildagliptin may have benefits for heart health beyond just controlling blood sugar. It can improve the function of your blood vessels, and it also helps reduce inflammation and oxidative stress in the body. These actions can slow down the hardening of your arteries, which improves your overall heart health.
Some studies suggest that long-term use may also lead to a lower risk of heart attacks and strokes. While Zomelis, Vildagliptin isn't officially approved for reducing these cardiovascular risks, including it in a diabetes treatment plan can still improve blood vessel health and lower the chances of death in high-risk patients.

Zomelis, Vildagliptin has attracted interest beyond diabetes, with studies exploring its use in other conditions related to metabolic problems and cellular stress.

• Researchers are investigating its potential to help with:
• Polycystic Ovary Syndrome (PCOS): Metformin may help improve ovulation and balance hormones.
• Nonalcoholic Fatty Liver Disease (NAFLD): Evidence suggests it can improve the liver's sensitivity to insulin.
• Cancer: Studies are looking into its potential to slow tumor growth.

• Neurodegenerative Disorders: Researchers are exploring its role in conditions like Alzheimer's, where insulin resistance in the brain may be a factor.

These studies show that Zomelis, Vildagliptin and similar metformin-based treatments have a broad impact on the body's metabolism, making it a subject of great scientific interest across many medical fields.

For adults with type 2 diabetes, the usual starting dose of vildagliptin is 50 mg, taken once or twice a day.

• When used alone (monotherapy), a 50 mg daily dose is often sufficient.
• However, when combined with other diabetes medications, especially metformin, a total daily dose of 100 mg is typically used to achieve the best blood sugar control.

Because the kidneys filter vildagliptin from the body, the dosage needs to be adjusted for patients with kidney problems. For those with moderate to severe kidney impairment, the recommended dose is lowered to 50 mg once a day. This helps prevent the drug from building up in the body and causing side effects. Doctors should regularly check kidney function, especially in older patients or those with existing kidney conditions.

The dose of vildagliptin can vary depending on the treatment plan. The recommended regimen is 50 mg in the morning and 50 mg in the evening. This twice-daily dose provides consistent inhibition of the DPP-4 enzyme, ensuring that incretin hormones remain active all day long. While some patients may prefer a single daily dose for convenience, a split dose is generally more effective for maintaining stable blood sugar levels.

If you forget to take a dose of your medication, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose completely.
Never take a double dose to make up for a missed one. Taking extra medication won't give you any added benefit and can increase the risk of side effects. For the best results in managing your blood sugar, it's most important to be consistent with your medication schedule.

You can take vildagliptin with or without food, as it won't affect how your body absorbs the medication.

• To get the most out of your treatment, you should also:
• Take your medication at the same time every day.

• Regularly check your blood sugar levels as your doctor recommends.
• Watch for signs of liver problems and tell your doctor if you experience symptoms like fatigue, jaundice, or dark urine.

Ultimately, clear communication with your doctor will help you stay on track and avoid preventable complications.

As people get older, their kidney function may decline, which should be considered when prescribing medication. While vildagliptin doesn't usually require a dosage change based just on age, it's a good idea to lower the dose if a patient has kidney problems. Regular lab tests are recommended to ensure the safe use of this medication in older adults.

Clinical trials have found that older adults generally tolerate vildagliptin as well as younger people. However, it's important to be cautious about the risk of low blood sugar (hypoglycemia), especially when taking vildagliptin with sulfonylureas or insulin. Regular check-ups can help ensure safety during long-term treatment.

It's generally recommended to avoid using vildagliptin during pregnancy because there is not enough data from controlled human studies to prove its safety. Animal studies have suggested potential risks to the fetus. Therefore, this medication should only be used if the potential benefits to the mother are much greater than any possible harm to the baby. For managing diabetes during pregnancy, insulin remains the preferred and safest treatment option.

It is not yet known whether vildagliptin can pass into human breast milk or what its effects on an infant would be. Because of this lack of safety information, nursing mothers are generally advised not to use this medication. If the treatment is absolutely necessary for the mother, alternative feeding methods for the baby should be considered to prevent any potential exposure to the drug.

The safety and effectiveness of vildagliptin in children have not yet been proven. Because clinical trials have only been conducted in adults, the drug is only approved for adult use. For this reason, it is uncommon to prescribe vildagliptin to younger patients, as there is not enough data to support its use in this age group.

International guidelines currently recommend against using vildagliptin in children and teenagers, except for those in clinical trials. For young people with Type 2 diabetes, the priority is lifestyle changes, followed by medications like metformin and, in some cases, insulin. Vildagliptin should not be prescribed for routine care until more research is available to determine if these types of treatments are safe and effective for this age group.

It's rare to overdose on vildagliptin, but it's important to be aware of the signs, as symptoms can start subtly and get worse over time.
Signs of an overdose can include:

• Stomach discomfort, such as nausea, vomiting, and abdominal pain.
• Neurological issues, including dizziness, confusion, sleepiness, and even seizures.

• General feelings of weakness, fatigue, or feeling unwell.
• Low blood sugar symptoms (if also taking insulin or sulfonylureas), such as sweating, trembling, heart palpitations, and pale skin.

The severity of an overdose can be worse in older adults or people with existing health issues, especially kidney or liver problems.

If someone has overdosed on this medication, the first step is to stabilize them immediately. Focus on keeping their airway clear, supporting their circulation, and checking their blood sugar quickly.

• If low blood sugar is confirmed or suspected, give them a fast-acting glucose source by mouth if they're awake. If they're not, administer intravenous (IV) dextrose.
• Monitor their heart and brain function continuously until their blood sugar and clinical condition are stable.
• If they took a large amount of the drug recently and their airway is protected, doctors may consider using activated charcoal to prevent further absorption.
• Regular lab tests will be done to check their electrolytes, liver function, and kidney function.

There is no specific antidote, and dialysis is not very effective. Treatment is focused on supportive care and managing the patient's symptoms. It's a good idea to contact a toxicologist or a poison control center as early as possible.

When handling the tablets, use dry hands and keep them in their original blister pack until you're ready to take a dose. Do not crush or split the pills unless your doctor has specifically instructed you to.
Swallow the tablet whole with water, and you can take it with or without food. To make sure the medication remains effective, store it away from excessive heat, light, and humidity. Also, never transfer the tablets into an unlabeled container.

To get rid of unused or expired tablets, use a pharmacy take-back program if one is available.
If you must throw them away at home, follow these steps:

• Mix the tablets (keep them whole, don't crush them) with an unappealing substance, like used coffee grounds or cat litter.
• Place the mixture in a sturdy, sealed container before putting it in the trash.
• Remember to remove or completely hide any personal information on the prescription label.

Any discomfort you feel is usually mild and temporary. To help reduce it, be sure to stay hydrated and eat regular meals. You can also consider taking a pain reliever, but only if it fits with your overall treatment plan.

You may feel briefly lightheaded, especially when you first start taking this medication. To avoid this, be sure to stand up slowly after sitting or lying down. If the lightheadedness continues, you should be checked for low blood sugar or side effects from other medications you're taking.

Stomach problems usually go away on their own. To help with them, you can:

• Eat small, frequent meals and avoid foods that are high in fat, which can make indigestion worse.
• Get enough fiber and fluids to help with constipation.
• If you experience worsening stomach pain, especially if it spreads to your back or is accompanied by vomiting, report it to your doctor immediately.

Feeling tired or weak is a non-specific but reported side effect. If these feelings don't go away, you should be evaluated for blood sugar fluctuations, anemia, thyroid problems, or drug interactions.

Although rare, acute pancreatitis is a serious side effect. Watch out for a sudden, severe pain in your upper abdomen that often spreads to your back, along with persistent nausea and vomiting.
If you suspect pancreatitis, stop taking vildagliptin immediately and seek urgent medical help. Your doctor will likely perform a blood test and imaging to check for it.

You might experience an increase in your liver enzyme levels (ALT/AST) without any symptoms. While rare, a more serious liver injury could occur, which would require you to stop taking the medication immediately.
If you have risk factors for liver problems, it's a good idea to have your liver function checked with blood tests before you start the medication and periodically afterward. Tell your doctor right away if you notice any symptoms like jaundice (yellowing of the skin), dark urine, severe fatigue, or pain in the upper right side of your abdomen.

Taking this medication by itself rarely causes low blood sugar (hypoglycemia). However, the risk increases significantly if you are also taking insulin or a sulfonylurea.
To help prevent this, you should:

• Eat regular meals.
• Always carry fast-acting carbohydrates (like glucose tablets or juice).
• Know the early warning signs of low blood sugar, such as trembling, sweating, a fast heartbeat, hunger, or confusion.
• If you have frequent low blood sugar events, your doctor may need to reduce the dose of your other medication.

Some people may experience an allergic skin reaction, such as a rash, hives, or itching. A more serious, but rare, side effect is angioedema (swelling beneath the skin), and this risk is higher if you are also taking an ACE inhibitor.
If you develop a widespread rash, have swelling in your face, or a reaction in your mouth or on other moist skin, stop taking the medication immediately and get medical help. Be sure to tell your doctor about the reaction so they can choose a different medication for you in the future.

Combining vildagliptin and metformin is a well-established and safe treatment option. They work together effectively because they each target a different aspect of blood sugar control: metformin reduces the amount of glucose your liver produces, while vildagliptin boosts the body's insulin secretion.

There are no known negative drug interactions between them. However, some people might experience digestive discomfort, which may require adjusting the dosage to improve tolerance

Combining vildagliptin with a sulfonylurea significantly increases the risk of low blood sugar (hypoglycemia). This happens because both medications work to boost insulin release.
To lower this risk, doctors often need to reduce the dose of the sulfonylurea. It's also crucial for patients to regularly check their blood sugar—both when fasting and after meals—and to be well-informed on how to recognize the symptoms of hypoglycemia.

Combining vildagliptin with insulin can greatly improve blood sugar control, but it also significantly raises the risk of low blood sugar (hypoglycemia). The main benefits of this approach are being able to reduce your overall insulin dose and better stabilize blood sugar levels.
To avoid symptomatic hypoglycemia, your doctor will need to carefully adjust your insulin and vildagliptin doses. It's also essential to monitor your blood glucose regularly.

The fixed-dose combination of vildagliptin and metformin is a key treatment for type 2 diabetes. The two drugs work together to lower HbA1c more effectively and with fewer side effects than taking a high dose of either one alone.
Even though this combination is generally well-tolerated, it's important to regularly check kidney function. This is because the body clears metformin through the kidneys, and poor kidney function can increase the risk of a serious side effect called lactic acidosis.

Combining vildagliptin with other diabetes medications like thiazolidinediones, alpha-glucosidase inhibitors, and SGLT2 inhibitors can be helpful, as they work together to improve blood sugar control. However, adding multiple drugs to your regimen requires careful planning by your doctor to prevent low blood sugar and stomach side effects.
It is important to avoid using a fixed-dose combination of these drugs unless your doctor has already confirmed that you tolerate each medication well on its own.

Vildagliptin doesn't have any major interactions with common blood pressure medications or statins. However, you should still be cautious:

• Beta-blockers can hide the typical symptoms of low blood sugar, like a fast heartbeat or trembling.
• ACE inhibitors can, in rare cases, increase the risk of angioedema (swelling beneath the skin).
• If you are also taking statins, your doctor may want to monitor your liver function, as both medications can affect the liver.

If you have ever had a reaction to vildagliptin or any of its ingredients, you should not take the medication again. This is because there's a risk of severe side effects like skin reactions or angioedema (swelling beneath the skin), which are considered absolute contraindications for its use.

You should avoid using vildagliptin in people with liver problems, as it can build up in the body and increase the risk of liver-related side effects. To avoid this, it's crucial to check a patient's liver function before and during treatment.

Patients who have experienced chronic pancreatitis should steer clear of vildagliptin due, to its association, with pancreatitis as reported with DPP‐IV inhibitors; it is advisable to opt for treatments to reduce the likelihood of a recurrence happening again.

Avoid using this medication if you have severe kidney impairment, defined as an eGFR below 30 mL/min/1.73 m². In these cases, your kidneys can't properly clear the drug, which increases your risk of side effects. It's best to consider alternative medications that are safer for people with kidney issues.

Increases in liver enzymes, specifically ALT and AST, have been noted in some patients. While these changes often don't cause any symptoms, routine liver function tests are needed to prevent the development of serious liver damage.

Before starting treatment, your liver enzyme levels should be checked. This monitoring should continue every three months for the first year, and periodically after that. If your liver enzyme levels consistently rise to more than three times the normal limit, the treatment should be stopped

Although rare, acute pancreatitis is a serious risk that you should be aware of. Watch for symptoms like severe abdominal pain that spreads to your back, along with nausea and vomiting. If you suspect these symptoms, you must stop taking the medication immediately and seek medical help.

While vildagliptin doesn't directly affect the heart, patients with existing heart conditions should be monitored for any potential issues with their blood sugar levels and for signs of ischemic events (reduced blood flow to the heart), especially when using it in combination with other medications. It is important to carefully consider a patient's heart health when personalizing their treatment.

When you combine vildagliptin with insulin or a sulfonylurea, the risk of low blood sugar (hypoglycemia) increases significantly.
To help prevent this, you should take a lower dose of the other medication, eat regular meals, and check your blood sugar often. It is also essential to know the symptoms of low blood sugar so you can act quickly.

For patients with reduced kidney function, it's important to adjust the dose of vildagliptin (Zomelis) to prevent the medication from building up in the body. Since the kidneys help remove vildagliptin, your doctor should check your kidney function before you start treatment and continue to monitor it. For those with mild to moderate kidney problems, a lower dose might be all that's needed to control blood sugar while keeping the risk of side effects low.

While Zomelis should not be used in people with severe liver problems, it may be an option for those with mild liver dysfunction if they are closely monitored. It is crucial to regularly check liver enzymes. If you experience persistent increases in these enzymes or develop symptoms like jaundice or unexplained fatigue, your doctor will need to re-evaluate the treatment and may decide to stop the medication.

When using Zomelis along with metformin or insulin or sulfonylureas to improve blood sugar control, however these combinations do bring a risk of hypoglycemia. It is important to take steps to mitigate this risk;

• Dosages of insulin or sulfonyureas may require a decrease.
• Regularly checking your blood sugar levels is advised.
• Patients ought to receive guidance on recognizing and handling hypoglycemia.

If you're taking Zomelis long-term, your doctor will need to monitor your health regularly. This includes:

• Kidney function tests every 6 to 12 months (or more often if you're at risk).
• Liver function tests before you start the medication and periodically during treatment.
• HbA1c tests every three months to check how well your blood sugar is controlled.
• Keeping an eye out for early signs of pancreatitis, such as severe stomach pain.

For the best results with Zomelis, it's important to combine the medication with a healthy lifestyle. This means sticking to a balanced diet of whole grains, lean proteins, and high-fiber foods, while limiting sugary and fatty foods. Regular physical activity also helps your body use insulin more effectively, which makes the medication work even better.

Regularly checking your blood sugar is key to managing your diabetes. By measuring both your fasting and after-meal glucose levels, you can see how stable your blood sugar is. This information helps you and your doctor make smart adjustments to your meal plan and spot potential problems early on, before they can lead to complications.

Drinking alcohol can change how your body handles glucose and can affect people taking Zomelis. If you're on this medication, you should be careful with alcohol, as it could increase your risk of both low blood sugar and liver problems. It's best to either avoid alcohol completely or limit your intake significantly to protect your health and safety.

You should seek immediate medical care if you experience any of the following symptoms:

• Severe abdominal pain that spreads to your back: This could be a sign of pancreatitis.
• Yellowing of your skin or the whites of your eyes: This can indicate liver problems.

• Persistent nausea, unexplained fatigue, or dark urine: These are also signs of potential liver issues.
• Dizziness, confusion, or excessive sweating: These symptoms could mean you are experiencing hypoglycemia (low blood sugar).

You should store Zomelis tablets at a controlled room temperature, typically between 20°C and 25°C. This helps keep the medication stable by protecting it from moisture and direct sunlight.

Every package of this medication has an expiration date. This date tells you when the drug may no longer be effective or safe to use. Always check the packaging and be sure to properly dispose of any expired medication to ensure your treatment is both safe and effective.

When you travel, keep your tablets in their original packaging with the prescription labels attached. It's best to pack your medication in your carry-on luggage so it isn't exposed to extreme temperatures in the cargo hold. Also, be sure to bring enough medication for your entire trip, plus some extra in case of travel delays.

Don't transfer your Zomelis tablets into other containers. Exposing the pills to air and moisture can make them less effective over time. Always leave the tablets in their original blister pack and only open one right before you take your dose. This will help ensure the medication works as it should throughout your treatment.