Pantoprazole is a proton pump inhibitor that is prescribed to help treat erosive esophagitis related to gastroesophageal reflux disease. Pantoprazole helps heal the esophagus from the damage caused by stomach acid. It may also be prescribed to help treat other conditions associated with excess stomach acid, including Zollinger-Ellison syndrome.

Generic Protonix


Pantosec, Pentab , Pantocid, Panaktive


Sun Pharma, Cipla, Alembic Pharma, Sava Medica


20 mg, 40 mg




Pantoprazole is used for the treatment of acidity,duodenal ulcer, heartburn, intestinal ulcers and stomach ulcers.

How it Works

Pantoprazole works by stopping the cells in the lining of the stomach from producing too much acid, and this helps to prevent ulcers from forming, or assists the healing process where damage has already occurred. Pantoprazole works by decreasing the amount of acid, and this can also help to reduce the symptoms of acid reflux disease, such as acidity,duodenal ulcer, heartburn, intestinal ulcers and stomach ulcers.

Common Side effects

Patients who take Pantoprazole may suffer from such side effects;

Abdominal pain,
Skin rashes


Pantoprazole is used for the treatment of extremely high levels of acidity in the stomach. This is a proton pump inhibitor or PPI that works by decreasing the amount of acid produced by the stomach. It causes rapid, effective and lasting inhibition of gastric acid secretion. Gastric secretory functions usually recover after the end of the treatment.


Every tablet of PROTONIX has 45.1 mg or 22.56 mg pantoprazole sodium sesquihydrate. This drug includes inactive components such as crospovidone, mannitol, sodium carbonate, calcium stearate, povidone, titanium dioxide, iron oxide, Polysorbate 80, triethyl citrate, hypromellose, sodium lauryl sulfate, propylene glycol and methacrylic acid copolymer. Other ingredients can be found in 40 mg PROTONIX like microcrystalline cellulose, yellow ferric oxide, and talc that are not found in 20 mg.


This drug is an effective medical treatment for the erosive esophagitis or otherwise known as heartburn due to gastroesophageal reflux disease or GERD as well as Zollinger-Ellison syndrome, a condition where the stomach produces too much acid.

Dosage and administration

Pantoprazole is taken in the morning with a dosage of 20 to 40 mg per day for the maintenance of peptic ulcer with a duodenal duration of two to four weeks. For benign gastric ulcer, it's consumed for 4 to 8 weeks. Intake of this medicine for H. pylori infection must be 40mg two times a day with amoxicillin or either clarithromycin or metronidazole. for patients suffering from Peptic ulcer with prophylaxis of NSAID needs a dosage of 20 mg per day. Patients should avoid being overdosed by this medicine as there is no certain treatment in case there is an overdose.


This drug is not recommended for lactating mothers, also children below 18 years old. For it can lead to atrophic gastritis.

Important Precautions

Long-term intake of this drug can cause bacterial overgrowth in the patient's GI tract. It can further cause hepatic impairment, so there must be consistent monitoring of liver function when consuming this drug.

Side effects

Diarrhoea, skin rashes, pain, giddiness, pruritus, chest pain, GI tract infections, eructation, bronchitis, headache, abdominal pain, anxiety, dyspepsia, nausea, neck pain, malaise or lassitude, hyperglycaemia, myalgia, insomnia, oedema, urinary frequency, UTI, flatulence, hyperlipidaemia constipation, rectal disorder, local site reaction, abnormalities in liver function, hypertonia, weakness, cough, pharyngitis, dyspnoea, rhinitis, upper respiratory tract infection, sinusitis and flu syndrome are the side effects of this medicine.


It has to be stored in room temperature. Keep it in a safe place away from children and pets. Pantoprazole should also be stored away from extreme heat, moisture and cold.

Rated: 4.7 / 5 based on 4.7 customer reviews.

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Note: does not imply any medical claims from this review.
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