Zomig (Zolmitriptan) is prescribed to help treat migraine attacks.





Astra Zeneca

Tablet, Orodispersible Tablet

2.5 mg


Out of Stock.


I. Introduction

Zomig, also known as zolmitriptan, is a medication for managing migraines. It belongs to the triptan class of drugs. It is specifically designed to alleviate the debilitating effects of migraines. Managing migraines has always presented challenges in medicine, where constant advancements are being made. However, with the introduction of Zomig, there has been a shift in how we approach this condition. This medication has relieved countless patients worldwide and has become a prominent player in migraine treatment. Zomig has undergone clinical trials and received approval from reputable regulatory bodies. The fact that it is widely accepted within the community speaks to its effectiveness and positive patient outcomes.

II. Uses

Zomig is a medication that is primarily used to help with migraines. It focuses on the phase of migraines, aiming to reduce their intensity and duration. One of the advantages of Zomig is its action in lowering the chance of recurring migraines and good patient tolerance. Unlike some medications, it has fewer restrictions for people with cardiovascular issues 1. Many migraine sufferers report experiencing relief within two hours after taking Zomig. The effects of Zomig can last up to 24 hours, which means frequent dosing is needed 1.

Here are some references that provide more information on Zomig:

  1. Medscape: This website provides detailed information on Zomig, including its dosing, indications, interactions, adverse effects, and more.
  2. Drugs.com: This website provides information on Zomig’s uses, dosage, side effects, and warnings.

III. How it Works

The way Zomig works is by narrowing the blood vessels around the brain. It also affects the release of substances that cause inflammation and can trigger pain and other symptoms of migraines. When interacting with neurotransmitters, Zomig's ability to act on serotonin (or 5 HT) receptors in the brain makes it effective. By influencing these neurotransmitters, it helps stop the progression of migraines. To understand migraines, we must dive into the nervous system's workings. Migraine episodes are not just headaches; they involve blood vessels and neurotransmitter changes. Zomig works by reducing these changes and interrupting the cascade of neurotransmitters providing relief.

IV. Dosage and Administration

Typically, doctors often suggest a dosage of 2.5mg for Zomig. The exact amount might differ depending on individual requirements. It is crucial to consult a physician to determine the dose. Zomig offers administration options, including oral tablets, orally disintegrating tablets, and nasal sprays to provide flexibility. The drug starts showing its effects within 2 hours. It continues to be effective for up to 24 hours. Dosage Adjustments may be necessary based on age, concurrent medications, and renal or hepatic function.

V. Composition

The main active ingredient in Zomig is called Zolmitriptan, which plays a role in its therapeutic effects. The other ingredients used in the formulation may. Typically, it includes substances that help bind the tablet together, fillers to ensure the right size and shape, and stabilizers to maintain the effectiveness of the medication. Zomig comes in forms such as oral tablets and nasal applications, providing patients with options that suit their preferences and meet their clinical needs.

VI. Side Effects

Summary of Possible Negative Effects: Similar to any medication, Zomig may cause side effects, but they are typically temporary and not severe. The occurrence and intensity of side effects are rare and minimal. Still, it is essential to acknowledge that, like with all medications, severe adverse reactions are possible.

VII. Common Side Effects

List and Brief Descriptions: Some notable side effects include feeling dizzy, experiencing fatigue, and occasionally having palpitations. Management and Mitigation: Most side effects are temporary and will resolve on their own. However, it is essential to monitor them and promptly address any unexpected symptoms that may arise.

VIII. Off-label Use

Zomig is a medication that is primarily used to treat migraines. However, it has been explored for off-label purposes such as treating cluster headaches 1When used off-label, Zomig has shown to be safe and effective 1There is ongoing research and clinical trials exploring potential new uses for Zomig 2.

Here are some references that provide more information on Zomig:

  1. Medscape: This website provides detailed information on Zomig, including its dosing, indications, interactions, adverse effects, and more.
  2. Drugs.com: This website provides information on Zomig’s uses, dosage, side effects, and warnings.

IX. Interaction

Please exercise caution when using Zomig with MAO inhibitors or SSRIs, as there may be serotonergic effects. It's also important to be aware that certain herbal supplements, such as St. Johns Wort, could increase the risk of side effects. Additionally, it's worth noting that alcohol can enhance the drowsiness effect of Zomig, while tobacco use may impact its metabolism. Please keep these factors in mind. Consult with your healthcare provider for further guidance.

X. Warning

Dangers: Just like any other medication, Zomig carries potential risks. It has been associated with increased blood pressure, feelings of tightness, and, in some cases, cardiovascular events. Precautions to Take: avoid consuming alcohol or taking medications with properties while using Zomig to prevent any negative interactions. Patients at Risk: Individuals with a history of cardiovascular diseases, stroke, or hypertension are considered at a higher risk when taking Zomig.

XI. Contraindication

Zomig should not be used by patients who have heart disease, cerebrovascular syndromes, or those who are known to be hypersensitive to zolmitriptan. It is recommended to exercise caution in patients with risk factors such as cholesterol, obesity, or a family history of heart disease, although it is not an absolute contraindication. In post-operative phases where other medications are being administered, careful consideration is required when deciding whether to use Zomig.

XII. Careful Administration

Prescribing Zomig requires an approach. Monitoring blood pressure, heart rate and any signs of chest discomfort is essential. Regular checkups are necessary to ensure the medication is tolerated and effective for the patient. Adjusting the dosage based on responses helps maximize the benefits of the treatment while minimizing any potential risks or side effects.

XIII. Important Precautions

Before beginning therapy, it is essential to provide a medical history with a particular focus on cardiovascular health before considering the prescription of Zomig. It is crucial to seek medical advice for any unusual symptoms or even subtle changes that may arise throughout treatment. When discontinuing using Zomig, it is generally not advisable to stop taking it. Instead, it is recommended to reduce the dosage in consultation with a physician who can provide guidance and support.

XIV. Administration to Specific Populations

Special Considerations for the Elderly: When it comes to adults, it is essential to reduce the dosage and monitor them closely due to the possibility of decreased kidney function. Safety Profile for Pregnant Women and Nursing Mothers: There is no data available on the effects of Zomig in this group. Therefore, its use should be carefully considered by weighing the benefits against any possible risks. Dosages and Precautions for Children: While Zomig can be used in children, dosage adjustments are necessary. It is crucial to monitor for any side effects that may occur closely.

XV. Overdosage

Symptoms and Presentation: If someone takes much of this medication, they may experience high blood pressure, serotonin syndrome, or, in severe cases, a sudden drop in circulation. Management and Treatment: It's crucial to seek medical help if an overdose occurs. Although no antidote is available, doctors will provide supportive care and treat the symptoms. Long-term Consequences: The long-term effects of overdosing are not well understood yet, but its important to continue monitoring the situation closely.

XVI. Storage

It is best to store Zomig in a place that's not too humid or exposed to light and where the temperature does not exceed 25°C (77°F). Generally, its effectiveness lasts two years after being manufactured, but you should check the packaging for the exact duration. If you have any expired or unused Zomig, it should be disposed of according to the waste guidelines in your area.

XVII. Handling Precautions

Safe Handling and Dispensation: A licensed pharmacist must oversee the dispensing process to ensure the packaging has not been tampered with. To avoid any risk of contamination, it is recommended to minimize contact and wear gloves if necessary. In case of contact with the skin, immediate cleansing is strongly advised. Usage and Handling by Healthcare Professionals: Healthcare professionals should understand Zomig's characteristics to ensure patient safety and maximize therapeutic effectiveness.

Rated: 5.0 / 5 based on 5.0 customer reviews.

Posted by priscilla on Feb 5, 2015 Verified Purchase

Cleared up migraine

I was prescribed this medication for my migraine headaches. In the US the price was over $100 a Pill. I was able to purchase this medication at a affordable price which made my quality of life even greater. My migraines were hindering me from getting my day today duties accomplished. This medication works fast and is very effective. It doesn't have many side effects either.

Note: buy-pharma.md does not imply any medical claims from this review.

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