Clobetasol Topical

Clobetasol Topical Cream is a corticosteroid prescribed to effectively manage a variety of skin disorders, such as eczema, psoriasis, etc.

Generic Dermovate Cream, ClobaDerm and Etrivex.


Tenovate, Clonate, Diplene AF, Lobate, Topinate

15g, 20g, 30g

GSK, Hegde and Hegde Pharma, Fulford India, Abbott, Systopic Laboratories




Clobetasol Topical

1. Introduction

Clobetasol Topical Overview: Clobetasol propionate, a corticosteroid, plays a crucial role in dermatology treatments. Its effectiveness stems from its anti-inflammatory, anti-itch, and blood vessel-constricting properties. Significance in dermatology care: Dermatologists often recommend Clobetasol Topical for its ability to improve skin conditions, ultimately improving the well-being of those affected.

2. Composition of Clobetasol Topical

Key components and their roles: The main active component, clobetasol propionate, reduces inflammation, relieves itching by lowering cytokine levels, and blocks allergic reactions. Varieties of this treatment come in the form of ointments, creams, gels, and shampoos, providing patients with a range of choices based on their requirements and preferences.

clobetasol ingredients

3. Uses of Clobetasol Topical

Main reasons, for usage;

Mostly recommended to treat psoriasis and eczema clobetasol propionate targets the growth of skin cells and intense itching commonly seen in these disorders.

Skin conditions managed with Clobetasol; Its uses also cover the treatment of lichen planus, discoid lupus erythematosus and various inflammatory skin ailments highlighting its range of therapeutic benefits.

4. Off-Label Uses of Clobetasol

  • Lesser Known Skin Conditions: Research indicates that clobetasol may be beneficial in treating other skin conditions beyond its approved uses. These include:
    • Vitiligo: Clobetasol has been investigated for its potential role in vitiligo management.
    • Alopecia Areata: Some studies suggest its effectiveness in reducing inflammation associated with alopecia areata, a condition causing hair loss.
  • Caution: However, caution is advised when using clobetasol off-label. Adverse effects and potential risks should be considered23.

5. How Clobetasol Topical Works

Clobetasol propionate works by engaging with receptors in the cytoplasm and ultimately blocking inflammatory mediators like phospholipase A2, which play a crucial role in causing skin inflammation. As a result of this interaction, there is a reduction in swelling, redness, and itchiness, which greatly improves the patient's skin condition and alleviates their discomfort.

6. Dosage and Administration

Dosage instructions to follow: It is important to use clobetasol, applying it no more than twice a day and not for more than two weeks without medical advice. When applying the medication, make sure to rub it into the affected areas without covering them unless instructed otherwise by a healthcare professional.

Treatment length: The duration of treatment varies based on how your body responds and the severity of your condition. It is best to keep the treatment period short as possible to reduce the likelihood of side effects.

7. Administration Details for Specific Populations

a. Administration to Elderly

Due to the heightened vulnerability to absorption throughout the body and potential systemic side effects, it is essential to consider factors and make appropriate dosage modifications.

b. Administration to Pregnant Women and Nursing Mothers

Safety while pregnant or breastfeeding has not been confirmed. It is advisable to proceed if the benefits outweigh the risks to the unborn child or nursing baby.

c. Administration to Children

When giving medication to children, it's important to be mindful of the dosage and how long they take it since kids are more susceptible to potentially harmful effects throughout their bodies.


8. Side Effects of Clobetasol Topical

a. Common Side Effects

Common side effects often seen are redness, flaky skin, and a burning feeling where the product is applied.

side effects clobetasol ingredients

b. Severe Side Effects

9. Important Precautions

Monitoring and Managing Side Effects

When to Seek Medical Attention

10. Interactions with Other Medications

Potential Drug Interactions

Clobetasol Topical might interact with prescribed medications, particularly other topical corticosteroids. It may also impact the absorption or efficacy of drugs processed by the liver. Patients should inform their healthcare provider about all the medications they are currently taking to avoid negative interactions.


clobetasol over the counter

Interaction with Over-the-Counter Products

Over the counter medications, supplements and even natural remedies have the potential to interact with clobetasol. It is important to be cautious when using products that contain corticosteroids or are meant for skin conditions as they could increase effects or lessen the effectiveness of the treatment.

11. Warnings and Contraindications

Conditions Under Which Clobetasol Should Not Be Used

People who are allergic to clobetasol propionate or any of the ingredients in Clobetasol Topical should not use it. Also, it's important to avoid using this medication on skin infections caused by viruses, bacteria, or fungi without treatment, with antimicrobial drugs.

Allergic Reactions and Hypersensitivity

If you develop skin irritations like dermatitis rash or swelling in an area it might be necessary to stop the treatment. In cases it's important for patients, with these symptoms to reach out to their healthcare provider without delay.

12. Handling and Storage of Clobetasol Topical

Proper Storage Conditions

To ensure that Clobetasol Topical remains effective and lasts long, it is important to store it in a dry place at room temperature. Keeping the container sealed when not in use is crucial to avoid contamination or breakdown of the active components.

Disposal of Expired or Unused Products

Make sure to dispose of any unnecessary clobetasol products correctly to prevent accidental exposure. It's best to seek advice from a pharmacist or local waste disposal service on disposal methods that adhere to local regulations.

13. Overdose and Emergency Management

Signs of Overdose

Experiencing an overdose of Clobetasol Topical is uncommon but possible, particularly when used excessively or for periods. Symptoms to watch out for include hypercortisolism and adrenal suppression. In these cases the chances of the drug being absorbed into the system increase.

Steps for Immediate Care

If you think there might be an overdose, stop taking the medication and seek medical help right away. The treatment will mainly involve addressing symptoms and providing support, which may include checking hormone levels and making adjustments to therapy.

14. Careful Administration

Guidelines for Safe Use

Patients need to be advised to use Clobetasol Topical on affected areas strictly following the prescribed amount and timeframe. It's important to avoid applying it on regions like the face, underarms, or groin area, unless specifically instructed by a healthcare professional.

Avoiding Common Mistakes During Application

Typical mistakes consist of usage, improper application methods and applying it on areas not recommended. These errors can be reduced through patient education and consistent supervision by medical professionals.

15. Handling Precautions

Personal Safety Measures During Application

Remember to wash your hands and, after using Clobetasol Topical avoid transferring the medication to different body parts or other people.

Preventing Accidental Exposure

It's important to make sure the medicine doesn't touch the eyes, mouth, or any other mucous membranes. Patients should understand how crucial it is not to share the medication with others to avoid use.

Rated: 5.0 / 5 based on 5.0 customer reviews.

Posted by Blackburne on Nov 9, 2018 Verified Purchase

Clobetasol Topical 0.05% 30 gm Cream

Many thanks to 'Buy-Pharma' for their great products and low prices. They wanted me to pay $150 for an 8oz tube in the US! I bought 3 8oz tubes through 'Buy-Pharma' for under $30!!! Thank you again all the people at 'Buy-Pharma'!

Note: does not imply any medical claims from this review.
Posted by ab on Aug 12, 2018 Verified Purchase


It is legit and works great. It took exactly 21 days to make it but it did arrive as promise.

Note: does not imply any medical claims from this review.
Posted by Hawke on Apr 1, 2018 Verified Purchase

Great Product

Great product, works the same as what I receive from my pharmacy in the U.S. Fast shipping and great communication. One can even speak with a rep. on the phone, they will even call should there be a reason to. Emails are answered in under an hour. Great products & customer service all around...and I have been a customer for at least a decade.

Note: does not imply any medical claims from this review.

Customers also bought

Popular Products

Similar Product